Modulation of gap junctional mechanisms during calcium-free induced field burst activity: A possible role for electrotonic coupling in epileptogenesis

Journal of Neuroscience

Volumn 14, Issue 7, 1994, Pages 4308-4317

  Perez Velazquez, Jose L ^a   Valiante, Taufik A ^a   Carlen, Peter L ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

electrotonic coupling; epilepsy; field potential; gap junctions; hippocampus; whole cell recordings

Indexed keywords

CALCIUM ION;

ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CELL PH; CELL SYNCHRONIZATION; CONTROLLED STUDY; EPILEPTOGENESIS; HIPPOCAMPUS; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; STAINING;

EID: 0028343428     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.14-07-04308.1994     Document Type: Article

References (51)

1. Andrew RD, Taylor CP, Snow RW, Dudek FE (1982) Coupling in rat hippocampal slices: dye transfer between CA1 pyramidal cells. Brain Res Bull 8:211-222.
2. Baimbridge KG, McLennan PMJ, Church J (1991) Bursting response to currents-evoked depolarization in rat CA1 pyramidal neurons is correlated with Lucifer Yellow dye coupling but not with the presence of calbindin-D28k. Synapse 7:269-277.
3. Bennet MVL (1977) Electrical transmission: a functional analysis and comparison to chemical transmission. In: Handbook of physiology, Sect I, The nervous system, Vol 1, Pt 1 (Kandel ER, ed), pp 357-416. Bethesda, MD: American Physiological Society.
4. Chen JCT, Chesler M (1992) Extracellular alkaline shifts in rat hippocampal slice are mediated by NMDA and non-NMDA receptors. J Neurophysiol 68:342-344.
5. Chesler M, Kaila K (1992) Modulation of pH by neuronal activity. Trends Neurosci 15:396-402.
6. Church J, Baimbridge K (1991) Exposure to high-pH medium increases the incidence and extent of dye coupling between rat hippocampal CA1 pyramidal neurons in film. J Neurosci 11:3289-3295.
7. Dermietzel R, Spray DC (1993) Gap junctions in the brain: where, what type, how many and why?. Trends Neurosci 16:186-192.
8. Dichter MA (1989) Cellular mechanisms of epilepsy and potential new treatment strategies. Epilepsia 30:S3-S12.
9. Dudek FE, Andrew RD, MacVicar BA, Snow RW, Taylor CP (1983) Recent evidence for and possible significance of gap junctions and electrotonic synapses in the mammalian brain. In: Basic mechanisms of neuronal hyperexcitability, pp 31-73. New York: Liss.
10. Dudek FE, Snow RW, Taylor CP (1986) Role of electrical interactions in synchronization of epileptiform bursts. In: Advances in neurology, Vol 44 (Delgado Escueta AV, Ward AA, Woodbury DM, Porter RJ, eds), pp 593-617. New York: Raven.
11. Frankenhaeuser B, Hodgkin AL (1957) The action of calcium on the electrical properties of squid axon. J Physiol (Lond) 137:218-244.
12. Giaume C, Korn H (1982) Ammonium sulfate induced uncouplings of crayfish axons with and without increased junctional conductance. Neuroscience 7:1723-1730.
13. Gutnick MJ, Lobel-Yaakov R (1983) Carbon dioxide uncouples dye coupled neuronal aggregates in neocortical slices. Neurosci Lett 42: 197-200.
14. Haas HL, Jefferys JGR (1984) Low-calcium field burst discharges of CA1 pyramidal neurones in rat hippocampal slices. J Physiol (Lond) 354:185-201.
15. Hamill OP, Marty A, Neher A, Sakmman B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution recording from cells and cell-free membrane patches. Pfluegers Arch 391:85-100.
16. Johnston MF, Simon SA, Ramon F (1980) Interactions of anaesthetics with electrical synapses. Nature 286:498-500.
17. Kayyali H, Durand D (1991) Effects of applied currents on epileptiform bursts in vitro. Exp Neurol 113:249-254.
18. Konnerth A, Heinemann U, Yaari Y (1986) Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. I. Development of seizurelike activity in low extracellular calcium. J Neurophysiol 56: 409-421.
19. Lancaster B, Adams PR (1986) Calcium-dependent current generating the afterhyperpolarization of hippocampal neurons. J Neurophysiol 55:1268-1282.
20. Lazrac A, Peracchia C (1993) Gap junction gating sensitivity to physiological internal calcium regardless of pH in Novikoff hepatoma cells. Biophysiol J 65:2002-2012.
21. MacVicar BA, Dudek FE (1981) Electrotonic coupling between pyramidal cells: a direct demonstration in rat hippocampal slices. Science 213:782-785.
22. MacVicar BA, Dudek FE (1982) Electrotonic coupling between granule cells of rat dentate gyrus: physiological and anatomical evidence. J Neurophysiol 47:579-592.
23. MacVicar BA, Jahnsen H (1985) Uncoupling of CA3 pyramidal neurons by propionate. Brain Res 330:141-145.
24. Miles R, Wong RKS (1987) Inhibitory control of local excitatory circuits in the guinea-pig hippocampus. J Physiol (Lond) 388:611-629.
25. Murphy AD, Hadley RD, Kater SB (1983) Axotomy-induced parallel increases in electrical and dye coupling between identified neurons of Helisoma. J Neurosci 3:1422-1429.
26. Naus CCG, Bechberger JF, Paul DL (1991) Gap junction gene expression in human seizure disorder. Exp Neurol 111:198-203.
27. Nuñez A, García Austt E, Buño W (1990) In vivo electrophysiological analysis of Lucifer Yellow coupled hippocampal pyramids. Exp Neurol 108:76-82.
28. O'Donnell P, Grace AA (1993) Dopaminergic modulation of dye coupling between neurons in the core and shell regions of the nucleus accumbens. J Neurosci 13:3456-3471.
29. Pedley TA (1984) Epilepsy and the human electroencephalogram. In: Electrophysiology of epilepsy (Schwartzkroin PA, Wheal HV, eds), pp 1-30. London: Academic.
30. Peinado A, Yuste R, Katz LC (1993) Extensive dye coupling between rat neocortical neurons during the period of circuit formation. Neuron 10:103-114.
31. Roos A, Boron WF (1981) Intracellular pH. Physiol Rev 61:296-434.
32. Schmalbruch H, Jahnsen H (1981) Gap junctions on CA3 pyramidal cells of guinea-pig hippocampus shown by freeze fracture. Brain Res 217:175-178.
33. Schweitzer JS, Patrylo PR, Dudek FE (1992) Prolonged field bursts in the dentate gyrus: dependence on low calcium, high potassium, and nonsynaptic mechanisms. J Neurophysiol 68:2016-2025.
34. Sharp AP, Thomas RC (1981) The effects of chloride substitution on intracellular pH in crab muscle. J Physiol (Lond) 312:71-80.
35. Shiosaka S, Yamamoto T, Hertzberg EL, Nagy JI (1989) Gap junction protein in rat hippocampus: correlative light and electron microscope immunohistochemical localization. J Comp Neurol 281:282-297.
36. Snow RW, Dudek FE (1984) Electrical fields directly contribute to action potential synchronization during convulsant-induced epileptiform bursts. Brain Res 323:114-118.
37. Somjen GG (1984) Acidification of interstitial fluid in hippocampal formation caused by seizures and spreading depression. Brain Res 311:186-188.
38. Spencer WA, Kandel ER (1961) Electrophysiology of hippocampal neurons. IV. Fast prepotentials. J Neurophysiol 24:272-285.
39. Spray DC, Harris AL, Bennet MVL (1981) Gap junctional conductance is a simple and sensitive function of intracellular pH. Science 211:712-715.
40. Spray DC, Ginzberg RD, Morales EA, Gatmaitan Z, Arias IM (1986) Electrophysiological properties of gap junctions between dissociated pairs of rat hepatocytes. J Cell Biol 103:135-144.
41. Stewart WW (1981) Lucifer dyes-highly fluorescent dyes for biological tracing. Nature 292:17-21.
42. Storm JF (1987) Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells. J Physiol 385: 733-759.
43. Taylor CP, Dudek FE (1982a) Synchronous neural afterdischarges in rat hippocampal slices without active chemical synapses. Science 218: 810-812.
44. Taylor CP, Dudek FE (1982b) A physiological test for electrotonic coupling between CA1 pyramidal cells in rat hippocampal slices. Brain Res 235:351-357.
45. Taylor CP, Dudek FE (1984) Synchronization without active chemical synapses during hippocampal afterdischarges. J Neurophysiol 52:145-155.
46. Terrar DA, Victory JGG (1988) Influence of halothane on electrical coupling in cell pairs isolated from guinea-pig ventricle. Br J Pharmacol 94:509-514.
47. Thomas RC (1984) Experimental displacement of intracellular pH and the mechanisms of its subsequent recovery. J Physiol (Lond) 354: 3-22.
48. + exchange is the major mechanism of pH regulation in cultured sympathetic neurons: measurements in single cell bodies and neuntes using a fluorescent pH indicator. Neuroscience 22:1093-1102.
49. Traub RD, Miles R, Wong RK (1989) Model of the origin of rhythmic population oscillations in the hippocampal slice. Science 243:1319-1324.
50. Walz W (1989) pH shifts evoked by neuronal stimulation in slices of rat hippocampus. Can J Physiol Pharmacol 67:577-581.
51. Yaari Y, Konnerth A, Heinemann U (1986) Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. II. Role of extracellular potassium. J Neurophysiol 56:424-437.