-
3
-
-
0027205671
-
Allele-Specific Replication Timing of Imprinted Gene Regions
-
of outstanding interest, Describes the existence of large DNA domains, all of which show early paternal/late maternal replication patterns; all individual imprinted loci examined are located within these domains.
-
(1993)
Nature
, vol.364
, pp. 459-463
-
-
Kitsberg1
Selig2
Brandeis3
Simon4
Keshet5
Driscoll6
Nicholls7
Cedar8
-
4
-
-
0026708177
-
Targeted Mutation of the DNA Methyltransferase Gene Results in Embryonic Lethality
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li1
Bestor2
Jaenisch3
-
5
-
-
0027378582
-
Role of DNA Methylation in Genomic Imprinting
-
of outstanding interest, Expression of imprinted genes is affected in the absence of DNA methylation. There is either bi-allelic expression, or repression of genes for which only one parental allele is usually expressed.
-
(1993)
Nature
, vol.366
, pp. 362-365
-
-
Li1
Beard2
Jaenisch3
-
6
-
-
0027924215
-
Genomic Imprinting: Silence of the Genes
-
(1993)
Nature
, vol.366
, pp. 302-303
-
-
Surani1
-
7
-
-
0027769524
-
A New Imprinted Gene Cloned by a Methylation-Sensitive Genome Scanning Method
-
of outstanding interest, Genome-wide scan for imprinted genes, using the potential methylation imprints and polymorphisms between parental loci as the basis for detecting such loci.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 5577-5582
-
-
Hatada1
Sugama2
Mukai3
-
11
-
-
0028365598
-
Allele Specific Inactivation of Insulin 1 and 2, in the Mouse Yolk Sac, Indicates Imprinting
-
of special interest, Demonstrates that imprinting can be highly tissue-specific.
-
(1994)
Nature Genet
, vol.6
, pp. 310-313
-
-
Giddings1
King2
Harman3
Flood4
Carnaghi5
-
14
-
-
0028147275
-
Igf2r and Igf2 Gene Expression in Androgenetic, Gynogenetic, and Parthenogenetic Preimplantation Mouse Embryos: Absence of Regulation by Genomic Imprinting
-
of special interest, Demonstrates that expression of these two genes is not affected by their parental origin during pre-implantation development, and that the silencing of a parental allele may occur at a later stage.
-
(1994)
Genes Dev
, vol.8
, pp. 290-299
-
-
Latham1
Doherty2
Scott3
Schultz4
-
15
-
-
0025368338
-
Androgenetic Mouse Embryonic Stem Cells are Pluripotent and Cause Skeletal Defects in Chimeras: Implications for Genetic Imprinting
-
(1990)
Cell
, vol.62
, pp. 251-260
-
-
Mann1
Gadi2
Harbison3
Abbondanzo4
Stewart5
-
16
-
-
0028364045
-
A Functional Analysis of Imprinting in Parthenogenetic Stem Cells
-
of special interest, in press, Describes the properties of parthenogenetic embryonic stem cells compared with those of androgenetic stem cells [15].
-
(1994)
Development
-
-
Allen1
Barton2
Hilton3
Norris4
Surani5
-
17
-
-
0026699762
-
Derivation of Pluripotent Embryonic Stem Cells from Murine Primordial Germ Cells in Culture
-
(1992)
Cell
, vol.70
, pp. 841-847
-
-
Matsui1
Zsebo2
Hogan3
-
20
-
-
0028260642
-
Allele Specificity of DNA Replication Timing in the Angelman/Prader-Willi Syndrome Imprinted Chromosomal Region
-
of special interest, Describes one region distal to the imprinted domain, where the only example so far of maternal early/paternal late replication was observed.
-
(1994)
Nature Genet
, vol.6
, pp. 41-46
-
-
Knoll1
Cheng2
Lalande3
-
21
-
-
0027400888
-
Maternal-Specific Methylation of the Imprinted Mouse Igf2r Locus Identifies the Expressed Locus as Carrying the Imprinting Signal
-
of special interest, Suggests that the methylation of an intronic CpG island may be a germline imprint and could act as a silencer of the paternal copy, where it is unmethylated.
-
(1993)
Cell
, vol.73
, pp. 61-71
-
-
Stöger1
Kubicka2
Liu3
Kafri4
Razin5
Cedar6
Barlow7
-
23
-
-
0027172684
-
Parental-Origin-Specific Epigenetic Modification of the Mouse H19 Gene
-
of special interest, Describes methylation of the paternal gene that is repressed in post-implantation embryos: methylation of critical sites in the promoter is absent in sperm and must occur post-zygotically.
-
(1993)
Nature
, vol.362
, pp. 751-754
-
-
Ferguson-Smith1
Sasaki2
Cattanach3
Surani4
-
24
-
-
0027203606
-
Epigenetic Mechanisms Underlying the Imprinting of the Mouse H19 Gene
-
of special interest, Essentially similar to [23 of outstanding interest]. In addition, there is preliminary evidence to show that an H19 transgene can be appropriately imprinted in two cases.
-
(1993)
Genes Dev
, vol.7
, pp. 1663-1673
-
-
Bartolomei1
Webber2
Brunkow3
Tilghman4
-
30
-
-
0027236694
-
The Ontogeny of Allele-Specific Methylation Associated with Imprinted Genes in the Mouse
-
of special interest, Describes methylation of specific sites within imprinted genes in the germline and pre-implantation development.
-
(1993)
EMBO J
, vol.12
, pp. 3669-3677
-
-
Brandeis1
Kafri2
Ariel3
Chaillet4
McCarrey5
Razin6
Cedar7
-
32
-
-
0027332051
-
Mechanistic Aspects of Genomewide Demethylation in the Preimplantation Mouse Embryo
-
of special interest, Experiments describe investigations on methylation of specific sites and their stability during pre-implantation development.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10558-10562
-
-
Kafri1
Gao2
Razin3
-
34
-
-
0027374296
-
Adult Phenotype in the Mouse can be Affected by Epigenetic Events in the Early Embryo
-
of special interest, Examines epigenetic modifications in reconstituted hybrid zygotes.
-
(1993)
Development
, vol.119
, pp. 933-942
-
-
Reik1
Römer2
Barton3
Surani4
Howlett5
Klose6
-
36
-
-
0028229427
-
Imprinting and X Chromosome Counting Mechanisms Determine Xist Expression in Early Mouse Development
-
of outstanding interest, in press, Paternal Xist expression up to the 8-cell stage is controlled by imprinting; thereafter an X-chromosome counting mechanism ensures appropriate Xist expression. A factor encoded by the maternal genome could be essential for the expression of Xist after the 8-cell stage, as Xist is rarely detected in androgenones after this time.
-
(1994)
Cell
-
-
Kay1
Barton2
Surani3
Rastan4
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