C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins

Blood

Volumn 83, Issue 11, 1994, Pages 3324-3331

  Elsner, Jörn ^a   Oppermann, Martin ^b   Czech, Wolfgang ^b   Kapp, Alexander ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3A; COMPLEMENT RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; PERTUSSIS TOXIN;

ARTICLE; COMPLEMENT ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; RESPIRATORY BURST; SIGNAL TRANSDUCTION;

EID: 0028339175     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v83.11.3324.3324     Document Type: Article

References (39)

1. Hugli TE: Structure and function of C3a anaphylatoxins. Curr Topics Microbiol Immunol 153:181, 1990
2. Rinaldo JE: Mediation of ARDS by leukocytes. Chest 89:590, 1986
3. Zilow G, Sturm A, Rother U, Kirschfink M: Complement activation and the prognostic value of C3a in patients at risk of adult respiratory distress syndrome. Clin Exp Immunol 79:151, 1990
4. Hosea S, Brown E, Hammer C, Frank M: Role of complement activation in a model of a adult respiratory distress syndrome. J Clin Invest 66:375, 1980
5. Till GO, Johnson KJ, Kunkel R, Ward PA: Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites. J Clin Invest 69:1126, 1982
6. Kapp A, Meske-Brand S, Maly FE, Muller W: Complement activation in patients with chronic polyarthritis measured by the level of complement fraction C3a in plasma. Z Rheumatol 43:2376, 1984
7. Abbink JJ, Kamp AM, Nuijens JH, Erenberg AJ, Swaak AJ, Hack CE: Relative contribution of contact and complement activation to inflammatory reactions in arthritic joints. Ann Rheum Dis 51:1123, 1992
8. Kapp A, Wokalek H, Schöpf E: Involvement of complement in psoriasis and atopic dermatitis measurement of C3a and C5a, C3, C4 and C1 inactivator. Arch Dermatol Res 277:359, 1985
9. Tagami H: The role of complement-derived mediators in inflammatory skin diseases. Arch Dermatol Res 284:S2, 1992 (suppl 1)
10. Bitter-Suermann D: The anaphylatoxins, in The Complement System. Rother K, Till G, (eds): New York, NY, Springer, 1988, p 367
11. Gerard NP, Gerard C: The chemotactic receptor for human C5a anaphylatoxin. Nature 349:614, 1991
12. Showell HJ, Glovsky MM, Ward PA: Morphological changes in human polymorphonuclear leukocytes induced by C3a in the presence and absence of cytochalasin B. Int Arch Allergy Appl Immunol 69:62, 1982
13. Nagata S, Glovsky MM, Kunkel SL: Anapylatoxin-induced neutrophil chemotaxis and aggregation. Int Arch Allergy Appl Immunol 82:4, 1987
14. Maly FE, Kapp A, Rother U: C5a-induced chemiluminescence of human granulocytes and its amplification by a serum factor. Immunobiol 164:90, 1983
15. Gerardy-Schahn R, Ambrosius D, Saunders D, Casaretto M, Mittler C, Karwarth C, Görgen S, Bitter-Suermann D: Characterization of C3a receptor-proteins on guinea pig platelets and human polymorphonuclear leukocytes. Eur J Immunol 19:1095, 1989
16. 125I-CSa binding. Biochemistry 31:11274, 1992
17. Bischoff SC, de Weck AL, Dahinden C: Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a. Proc Natl Acad Sci USA 87:6813, 1990
18. Kretzschmar T, Jeromin A, Gietz C, Bautsch W, Klos A, Köhl J, Rechkemmer G, Bitter-Suermann D: Chronic myelogenous leukemia-derived basophilic granulocytes express a functional active receptor for the anaphylatoxin C3a. Eur J Immunol 23:558, 1993
19. Oppermann M, Schulze M, Götze O: A sensitive enzyme immunoassay for the quantification of human C5a/C5a-desArg anaphylatoxin using a monoclonal antibody with specificity for a neoepitope. Complement Inflamm 8:13, 1991
20. Püschel GP, Oppermann, Muschol W, Götze O, Jungermann K: Increase of glucose and lactate output and decrease of flow by human anaphylatoxin C3a but not C5a in perfused rat liver. FEBS Letters 243:83, 1989
21. 2-terminal domain. J Immunol 151:3785, 1993
22. Kapp A, Zeck-Kapp G, Danner M, Luger TA: Human granulocyte-macrophage colony stimulating factor: An effective direct activator of human polymorphonuclear neutrophilic granulocytes. J Invest Dermatol 91:49, 1988
23. Maly FE, Cross AR, Jones OTG, Wolf-Vorbeck G, Walker C, Dahinden CA, De Week AL: The superoxide generating system of B cell lines. Structural homology with the phagocytic oxidase and triggering via surface Ig. J Immunol 140:2334, 1988
24. Wymann MP, Kernen P, Deranleau DA, Baggiolini M: Respiratory burst oscillations in human neutrophils and their correlation with fluctuations in apparent cell shape. J Biol Chem 264:15829, 1989
25. Maly FE, Urwyler A, Rolli HP, Dahinden CA, de Weck AL: A single-photon imaging system for the simultaneous quantitation of luminescent emissions from multiple samples. Anal Biochem 168:462, 1988
26. Maly FE, Vitooz M, Urwyler A, Koshikawa K, Schleinkofer L, de Weck AL: A dual microtiter plate (192) sample luminometer employing computer-aided single-photon imaging applicable in the light emiting reaction. J Immunol Meth 122:91, 1989
27. Roesler J, Emmendörffer A, Elsner J, Zeidler C, Lohmann-Matthes ML, Welte: In vitro functions of neutrophils induced by treatment with rhG-CSF in severe congenital neutropenia. Eur J Haematol 46:112, 1991
28. Hundt M, Schmidt RE: The glycosylphosphatidylinositol-linked Fcγ receptor III represents the dominant receptor structure for immune complex activation of neutrophils. Eur J Immunol 22:811, 1992
29. Kernen P, Wymann MP, von Tscharner V, Deranleau DA, Tai PC, Spry CJ, Dahinden CA, Baggiolini M: Shape changes, exocytosis, and cytosolic free calcium changes in stimulated eosinophils. J Clin Invest 87:2012, 1991
30. Elsner J, Kaever V, Emmendörffer A, Breidenbach T, Lohmann-Matthes ML, Roesler J: Heterogeneity in the mobilization of cytoplasmic calcium by human polymorphonuclear leukocytes in response to FMLP, C5a and IL-8/NAP-1. J Leukoc Biol 51:77, 1992
31. Elsner J, Roesler J, Emmendörffer A, Lohmann-Matthes ML, Weite K: Abnormal regulation in the signal transduction in neutrophils from patients with severe congenital neutropenia: Relation of impaired mobilization of cytosolic free calcium to altered chemotaxis, superoxide anion generation and F-actin content. Exp Hematol 21:38, 1993
32. Elsner J, Norgauer J, Dobos GJ, Emmendörffer A, Schöpf E, Kapp A, Roesler J: Flow cytometry reveals different lag times in rapid cytoplasmic calcium elevations in human neutrophils in response to N-formyl peptide. J Cell Physiol 157:637, 1993
33. Schwenk U, Morita E, Engel R, Schröder JM: Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid. J Biol Chem 267:12482, 1992
34. 2+, and protein kinase C. J Bioenerg Biomembr 20:709, 1988
35. Bokisch VA, Müller-Eberhard HJ: Anaphylatoxin inactivator of human plasma. Its isolation and characterization as a carboxypeptidase. J Clin Invest 49:2427, 1970
36. Webster RO, Hong SR, Johnston RB Jr, Henson PM: Biological effects of the human complement fragments C5a and C5a desArg on neutrophil function. Immunopharmacol 2:201, 1980
37. Elsner J, Oppermann M, Czech W, Dobos G, Schöpf E, Norgauer J, Kapp A: C3a activates reactive oxygen species production and intracellular calcium transients in human eosinophils. Eur J Immunol 24:518, 1994
38. Dillon SB, Verghese MW, Snyderman R: Signal transduction in cells following binding of chemoattractants to membrane receptors. Virchows Arch B Cell Pathol 55:65, 1988
39. Baggiolini M, Boulay F, Badewey A, Curnutte JT: Activation of neutrophil leukocytes: Chemoattractant receptors and respiratory burst. FASEB J 7:1004, 1993