메뉴 건너뛰기




Volumn 37, Issue 10, 1994, Pages 1535-1542

Synthesis and Characterization of Radioiodinated N-(3-Iodopropen-1-yl)-2β-carbomethoxy-3β-(4-chlorophenyl)tropanes: Potential Dopamine Reuptake Site Imaging Agents

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 [(4 FLUOROPHENYL)(PHENYL)METHOXY]ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; 3BETA (4 CHLOROPHENYL) 8 (3 IODOALLYL) 2BETA NORTROPANECARBOXYLIC ACID METHYL ESTER; COCAINE; DOPAMINE; IODINE 123; IODINE 125; MAZINDOL; RADIOPHARMACEUTICAL AGENT; TROPANE DERIVATIVE; UNCLASSIFIED DRUG; VANOXERINE;

EID: 0028337480     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00036a020     Document Type: Article
Times cited : (90)

References (35)
  • 1
    • 0019229205 scopus 로고
    • Saturable [3H] cocaine binding in central nervous system of mouse
    • Reith, M. E.; Sherdhen, H.; Latjtha, A. Saturable [3H] cocaine binding in central nervous system of mouse. Life Sci. 1980, 27, 1055-1062
    • (1980) Life Sci. , vol.27 , pp. 1055-1062
    • Reith, M.E.1    Sherdhen, H.2    Latjtha, A.3
  • 2
    • 0022346569 scopus 로고
    • Sodiumindependent binding of [3H] cocaine in mouse striatum in serotonin related
    • Reith, M. E.; Meisler, B. E.; Sershen, H.; Latjtha, A. Sodiumindependent binding of [3H] cocaine in mouse striatum in serotonin related. Brain Res. 1985, 342, 145-148
    • (1985) Brain Res. , vol.342 , pp. 145-148
    • Reith, M.E.1    Meisler, B.E.2    Sershen, H.3    Latjtha, A.4
  • 3
    • 0023632425 scopus 로고
    • High affinity stereospecific binding of [3H] cocaine in striatum and its Relationship to the Dopamine Transporter
    • Calligaro, D. O.; Eldefrawi, M. E. High affinity stereospecific binding of [3H] cocaine in striatum and its Relationship to the Dopamine Transporter. Membrane Biochem. 1988, 7, 87-106
    • (1988) Membrane Biochem. , vol.7 , pp. 87-106
    • Calligaro, D.O.1    Eldefrawi, M.E.2
  • 5
    • 0024464860 scopus 로고
    • Effects of Cocaine and Related Drugs in Nonhuman Primates
    • [3H] Cocaine Binding Sites in Caudate-putamen.
    • Madras, B. K.; Fahey, M. A.; Bergman, J.; Canfield, D. R.; Spealman, R. D. Effects of Cocaine and Related Drugs in Nonhuman Primates. [3H] Cocaine Binding Sites in Caudate-putamen. J. Pharmacol. Exp. Ther. 1989, 251, 131
    • (1989) J. Pharmacol. Exp. Ther. , vol.251 , pp. 131
    • Madras, B.K.1    Fahey, M.A.2    Bergman, J.3    Canfield, D.R.4    Spealman, R.D.5
  • 6
    • 0021893325 scopus 로고
    • Sodium Dependent [3H]Cocaine Binding Associated With Dopamine Uptake Sites In The Rat Striatum and Human Putamen Decrease After Dopaminergic Deneravation and in Parkinsons Disease
    • Shoemaker, H.; Pimoule, C.; Arbilla, S.; Scatton, B.; Javoy-Agid, F.; Langer, S. Z. Sodium Dependent [3H]Cocaine Binding Associated With Dopamine Uptake Sites In The Rat Striatum and Human Putamen Decrease After Dopaminergic Deneravation and in Parkinsons Disease. Naunyn-Schmiedeberg's Arch. Pharmacol. 1985, 239, 227
    • (1985) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.239 , pp. 227
    • Shoemaker, H.1    Pimoule, C.2    Arbilla, S.3    Scatton, B.4    Javoy-Agid, F.5    Langer, S.Z.6
  • 7
    • 0023265754 scopus 로고
    • Cocaine Receptors Are Related to Self-Administration of Cocaine
    • Ritz, M. C.; Lamb, J. R.; Goldberg, S. R.; Kuhar, M. J. Cocaine Receptors Are Related to Self-Administration of Cocaine. Science 1987, 237, 1219-1223
    • (1987) Science , vol.237 , pp. 1219-1223
    • Ritz, M.C.1    Lamb, J.R.2    Goldberg, S.R.3    Kuhar, M.J.4
  • 8
    • 0026566383 scopus 로고
    • Cocaine Receptor: Biochemical Characterization and Structure-Activity Relationships of Cocaine Analogues at The Dopamine Transporter
    • Carroll, F. I.; Lewin, A. H.; Boja, J. W.; Kuhar, M. J. Cocaine Receptor: Biochemical Characterization and Structure-Activity Relationships of Cocaine Analogues at The Dopamine Transporter. J. Med. Chem. 1992, 35, 969-981
    • (1992) J. Med. Chem. , vol.35 , pp. 969-981
    • Carroll, F.I.1    Lewin, A.H.2    Boja, J.W.3    Kuhar, M.J.4
  • 9
    • 0013920522 scopus 로고
    • Dopamine and Brian Function
    • Hornykiewicz, O. Dopamine and Brian Function. Pharmacol. Rev. 1966, 18, 925-961
    • (1966) Pharmacol. Rev. , vol.18 , pp. 925-961
    • Hornykiewicz, O.1
  • 10
    • 0023748070 scopus 로고
    • Tardive Dyskinesia, Dopamine Receptors, and Neuroleptic Damage to Cell Membranes
    • Seeman, P. Tardive Dyskinesia, Dopamine Receptors, and Neuroleptic Damage to Cell Membranes. J. Clin. Psychopharmacol. 1988, 8 (suppl.), 35-95
    • (1988) J. Clin. Psychopharmacol. , vol.8 , pp. 35-95
    • Seeman, P.1
  • 12
    • 0019462450 scopus 로고
    • Dopamine Receptors, Neuroleptics and Schizophrenia
    • Snyder, S. H. Dopamine Receptors, Neuroleptics and Schizophrenia. Am. J. Psychiatry 1981, 138, 460-464
    • (1981) Am. J. Psychiatry , vol.138 , pp. 460-464
    • Snyder, S.H.1
  • 16
    • 0026696704 scopus 로고
    • Synthesis of Carbon-11 Labeled Iodinated Cocaine Derivatives and Their Distribution in Baboon Brian Measured Using Positron Emission Tomography
    • Yu, D.-W.; Gately, S. J., Wolf, A. P.; MacGregor, R.; Fowler, J. S.; Dewey, S. I.; Schlyer, D. J. Synthesis of Carbon-11 Labeled Iodinated Cocaine Derivatives and Their Distribution in Baboon Brian Measured Using Positron Emission Tomography. J. Med. Chem. 1992, 35, 2178-2183
    • (1992) J. Med. Chem. , vol.35 , pp. 2178-2183
    • Yu, D.-W.1    Gately, S.J.2    Wolf, A.P.3    MacGregor, R.4    Fowler, J.S.5    Dewey, S.I.6    Schlyer, D.J.7
  • 18
    • 0023861629 scopus 로고
    • Synthesis of [18F]GBR 13119 A Presynaptic Dopamione Uptake Antagonist
    • Kilbourn, M. R.; Haka, M. S. Synthesis of [18F]GBR 13119 A Presynaptic Dopamione Uptake Antagonist. Appl. Radiat. Isot. 1988, 39, 279-282
    • (1988) Appl. Radiat. Isot. , vol.39 , pp. 279-282
    • Kilbourn, M.R.1    Haka, M.S.2
  • 19
    • 0023728742 scopus 로고
    • Vivo Binding of [18F]GBR 13119 To The Brain Dopamine Uptake System
    • Kilbourn, M. R. In Vivo Binding of [18F]GBR 13119 To The Brain Dopamine Uptake System. Life Sci. 1988, 42, 1347-1353
    • (1988) Life Sci. , vol.42 , pp. 1347-1353
    • Kilbourn, M.R.1
  • 20
    • 45249131090 scopus 로고
    • Biodistribution, Dosimetry, Metabolism and Monkey PET Studies of [18F]GBR 13119. Imaging The Dopamine Uptake System In Vivo
    • Kilbourn, M. R.; Carey, J. E.; Koeppe, R. A.; Haka, M. S.; Hutchins, G. A.; Sherman, P. S.; Kuhl, D. E. Biodistribution, Dosimetry, Metabolism and Monkey PET Studies of [18F]GBR 13119. Imaging The Dopamine Uptake System In Vivo. Nucl. Med. Biol. 1989, 16, 569-576
    • (1989) Nucl. Med. Biol. , vol.16 , pp. 569-576
    • Kilbourn, M.R.1    Carey, J.E.2    Koeppe, R.A.3    Haka, M.S.4    Hutchins, G.A.5    Sherman, P.S.6    Kuhl, D.E.7
  • 21
  • 22
    • 0025314764 scopus 로고
    • Synthesis of 3-Arylecogonine Analogues as Inhibitors of Cocaine Binding and Dopamine Uptake
    • Kline, R. H.; Wright, J.; Fox, K. M.; Eldefrawi, M. E. Synthesis of 3-Arylecogonine Analogues as Inhibitors of Cocaine Binding and Dopamine Uptake. J. Med. Chem. 1990, 33, 2024-2027
    • (1990) J. Med. Chem. , vol.33 , pp. 2024-2027
    • Kline, R.H.1    Wright, J.2    Fox, K.M.3    Eldefrawi, M.E.4
  • 23
    • 0026009418 scopus 로고
    • Synthesis, Ligand Binding, QSAR, and CoMFA Study of 3β-(p-Substituted phenyl)tropane-2β-carboxylic Acid Methyl Esters
    • Carroll, F. I.; Gao, Y.; Rahman, M. A.; Abraham, P.; Parham, K.; Lewin, A. H.; Lewin, A. H.; Boja, J. H.; Kuhar, M. J. Synthesis, Ligand Binding, QSAR, and CoMFA Study of 3β-(p-Substituted phenyl)tropane-2β-carboxylic Acid Methyl Esters. J. Med. Chem. 1991, 34, 2719-2725
    • (1991) J. Med. Chem. , vol.34 , pp. 2719-2725
    • Carroll, F.I.1    Gao, Y.2    Rahman, M.A.3    Abraham, P.4    Parham, K.5    Lewin, A.H.6    Lewin, A.H.7    Boja, J.H.8    Kuhar, M.J.9
  • 28
    • 0026667562 scopus 로고
    • Vivo Imaging of Dopamine Reuptake Sites in the Primate Brain Using Single Photon Emission Computed Tomography (SPECT) and Iodine-123 Labeled RTI-55
    • Shaya, E.; Scheffel, U.; Dannals, R. F.; Ricaurte, G. A.; Carroll, F. I.; Wagner, H. N.; Kuhar, M. J.; Wong, D. F. In Vivo Imaging of Dopamine Reuptake Sites in the Primate Brain Using Single Photon Emission Computed Tomography (SPECT) and Iodine-123 Labeled RTI-55. Synapse 1992, 10, 169-172
    • (1992) Synapse , vol.10 , pp. 169-172
    • Shaya, E.1    Scheffel, U.2    Dannals, R.F.3    Ricaurte, G.A.4    Carroll, F.I.5    Wagner, H.N.6    Kuhar, M.J.7    Wong, D.F.8
  • 29
    • 0027463320 scopus 로고
    • Synthesis of a Radiotracer for Studying Dopamine Uptake Sites In Vivo Using PET: 2β-Carbomethoxy-3β-(4-fluorophenyl)-[N-11C-methyl]tropane ([11C]CFT or [11C]- WIN-35,428)
    • Dannals, R. F.; Neumyer, J. L.; Milius, R. A.; Ravert, H. T.; Wilson, A. A.; Wagner, Jr., H. N. Synthesis of a Radiotracer for Studying Dopamine Uptake Sites In Vivo Using PET: 2β-Carbomethoxy-3β-(4-fluorophenyl)-[N-11C-methyl]tropane ([11C]CFT or [11C]- WIN-35,428). J. Lab. Comp. Radiopharm. 1993, 33, 147-152
    • (1993) J. Lab. Comp. Radiopharm. , vol.33 , pp. 147-152
    • Dannals, R.F.1    Neumyer, J.L.2    Milius, R.A.3    Ravert, H.T.4    Wilson, A.A.5    Wagner, H.N.6
  • 31
    • 0025895074 scopus 로고
    • Synthesis and Receptor Binding of N-Substituted Tropane Derivatives. High Affinity Ligands for the Cocaine Receptor
    • Milius, R. A.; Saha, J. K.; Madras, B. K.; Neumeyer, J. L. Synthesis and Receptor Binding of N-Substituted Tropane Derivatives. High Affinity Ligands for the Cocaine Receptor. J. Med. Chem. 1991, 34, 1728-1731
    • (1991) J. Med. Chem. , vol.34 , pp. 1728-1731
    • Milius, R.A.1    Saha, J.K.2    Madras, B.K.3    Neumeyer, J.L.4
  • 32
    • 0001441665 scopus 로고
    • Preparation of Iodoallylic Alcohols Via Hydrostannylation Spectroscopic Proof of Structures
    • Jung, M. E.; Light, L. A. Preparation of Iodoallylic Alcohols Via Hydrostannylation Spectroscopic Proof of Structures. Tetrahedron Lett. 1982, 23, 3851-3854
    • (1982) Tetrahedron Lett. , vol.23 , pp. 3851-3854
    • Jung, M.E.1    Light, L.A.2
  • 33
    • 0023186425 scopus 로고
    • Selective labeling of serotonin uptake sites in rat brain by [3H]-citalopram contrasted to labeling to multiple sites by [3H]-imipramine
    • D'Amato, R. J. D.; Largent, B. L.; Snowman, A. M.; Snyder, S. H. Selective labeling of serotonin uptake sites in rat brain by [3H]-citalopram contrasted to labeling to multiple sites by [3H]-imipramine. J. Pharm. Exp. Ther. 1987, 2242, 364-371
    • (1987) J. Pharm. Exp. Ther. , vol.2242 , pp. 364-371
    • D'Amato, R.J.D.1    Largent, B.L.2    Snowman, A.M.3    Snyder, S.H.4
  • 34
    • 0019061918 scopus 로고
    • Ligand: A Versatile Computerized Approach For characterization of Ligand-Binding Systems
    • Munson, P.; Roabard, D. Ligand: A Versatile Computerized Approach For characterization of Ligand-Binding Systems. Anal. Biochem. 1980, 107, 229-239
    • (1980) Anal. Biochem. , vol.107 , pp. 229-239
    • Munson, P.1    Roabard, D.2
  • 35
    • 0025181821 scopus 로고
    • Synthesis and Characterization of Iodobenzamide Analogues: Potential D-2 Dopamine Receptor Imaging Agents
    • Murphy, R. A.; Kung, H. F.; Kung, M.-P.; Billings J. Synthesis and Characterization of Iodobenzamide Analogues: Potential D-2 Dopamine Receptor Imaging Agents. J. Med. Chem. 1990, 33, 171-178
    • (1990) J. Med. Chem. , vol.33 , pp. 171-178
    • Murphy, R.A.1    Kung, H.F.2    Kung, M.-P.3    Billings, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.