Sequential protein kinase reactions controlling cell growth and differentiation

Current Opinion in Cell Biology

Volumn 6, Issue 2, 1994, Pages 230-238

  Johnson, Gary L ^a,b   Vaillancourt, Richard R ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; GROWTH FACTOR RECEPTOR; GUANOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; RAS PROTEIN;

CELL DIFFERENTIATION; CELL GROWTH; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIFFERENTIATION; CELL DIVISION; GTP-BINDING PROTEINS; HUMANS; MODELS, BIOLOGICAL; PROTEIN KINASES; PROTEIN-TYROSINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

EID: 0028333768     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0955-0674(94)90141-4     Document Type: Article

References (73)

1. 1 Cyclins
2. Signalling by Receptor Tyrosine Kinases
3. Autophosphorylation of the PDGF Receptor in the Kinase Insert Region Regulates Interactions with Cell Proteins
4. PDGF β-Receptor Stimulates Tyrosine Phosphorylation of GAP and Association of GAP with a Signalling Complex
5. Primary Response Genes Induced by Growth Factors and Tumor Promoters
6. Transcription Factor Phosphorylation: A Link Between Signal Transduction and the Regulation of Gene Expression
7. Oncogenes and Signal Transduction
8. SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins
9. SH2 and SH3 Domains: From Structure to Function
10. In Vivo Binding Properties of SH2 Domains from GTPase-Activating Protein and Phosphatidylinositol 3-Kinase
11. IRS-1 Activates Phosphatidylinositol 3-Kinase by Associating with Src Homology 2 Domains of p85
12. Structure of an SH2 Domain of the p85 α Subunit of Phosphatidylinositol-3-OH Kinase
13. Transcription Factor p91 Interacts with the Epidermal Growth Factor Receptor and Mediates Activation of the c-fos Gene Promoter
14. Ras-Independent Growth Factor Signaling by Transcription Factor Tyrosine Phosphorylation
15. Induction by EGF and Interferon-γ of Tyrosine Phosphorylated DNA Binding Proteins in Mouse Liver Nuclei
16. A Common Nuclear Signal Transduction Pathway Activated by Growth Factor and Cytokine Receptors
17. PDGF Stimulation of Inositol Phospholipid Hydrolysis Requires PLC-γ 1 Phosphorylation on Tyrosine Residues 783 and 1254
18. Activated Type I Phosphatidylinositol Kinase is Associated with the Epidermal Growth Factor (EGF) Receptor Following EGF Stimulation
19. PDGF β-Receptor Stimulates Tyrosine Phosphorylation of GAP and Association of GAP with a Signaling Complex
20. SH2-Containing Phosphotyrosine Phosphatase as a Target of Protein-Tyrosine Kinases
21. Association of Sos Ras Exchange Protein with Grb2 is Implicated in Tyrosine Kinase Signal Transduction and Transformation
22. The Son of Sevenless Gene Product: A Putative Activator of Ras
23. Crystal Structure of a Src-Homology 3 (SH3) Domain
24. Identification of a Protein that Binds to the SH3 Region of Abl and is Similar to Bcr and GAP-rho
25. Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site
26. 2+/Calmodulin-Dependent Protein Kinase II is Phosphorylated by Protein Kinase C in Vitro
27. The Regulation of Transcription by Phosphorylation
28. ++-Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases
29. The Mitogen-Activated Protein Kinase Signal Transduction Pathway
30. Signal Transduction via the MAP Kinases: Proceed at Your Own RSK
31. A Drosophila SH2-SH3 Adaptor Protein Implicated in Coupling the Sevenless Tyrosine Kinase to an Activator of Ras Guanine Nucleotide Exchange, Sos
32. ras1 Activation and Binds to Sevenless and Sos Proteins in Vitro
33. Guanine-Nucleotide-Releasing Factor hSos1 Binds to Grb2 and Links Receptor Tyrosine Kinases to Ras Signalling
34. Grb2 Mediates the EGF-Dependent Activation of Guanine Nucleotide Exchange on Ras
35. ras Through the Formation of a Complex of Receptor, Grb2 Adaptor Protein, and Sos Nucleotide Exchange Factor
36. ras Proteins Bind to the Amino-Terminal Regulatory Domain of c-Raf-1
37. Direct Interaction of Ras and the Amino-Terminal Region of Raf-1 in Vitro
38. Mammalian Ras Interacts Directly with the Serine/Threonine Kinase Raf
39. Raf-1 Activates MAP Kinase-Kinase
40. The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product
41. Insulin-Stimulated Microtubule-Associated Protein Kinase is Phosphorylated on Tyrosine and Threonine in Vivo
42. Nuclear Localization and Regulation of Erk- and Rsk-Encoded Protein Kinases
43. A Growth Factor-Induced Kinase Phosphorylates the Serum Response Factor at a Site that Regulates its DNA-Binding Activity
44. MAPKAP Kinase-2: A Novel Protein Kinase Activated by Mitogen-Activated Protein Kinase
45. Identification of MAPKAP Kinase-2 as a Major Enzyme Responsible for the Phosphorylation of the Small Mammalian Heat Shock Proteins
46. A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf
47. Mos Stimulates MAP Kinase in Xenopus Oocytes and Activates a MAP Kinase Kinase in Vitro
48. A Conserved Kinase Cascade for MAP Kinase Activation in Yeast
49. Conservation and Reiteration of a Kinase Cascade
50. An Osmosensing Signal Transduction Pathway in Yeast
51. Functional Homology of Protein Kinases Required for Sexual Differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae Suggest a Conserved Signal Transduction Module in Eukaryotic Organisms
52. ras by G Protein-Coupled Receptor Agonists in Fibroblasts
53. 1-Coupled Acetylcholine Muscarinic m2 Receptor Activation of Mitogen-Activated Protein (MAP) Kinase Kinase and MAP Kinase
54. 1-Mediated Activation of p44 Mitogen-Activated Protein Kinase and S6 Kinase by Growth Factors in Hamster Fibroblasts
55. Rap V12 Antagonizes Ras-Dependent Activation of ERK1 and ERK2 by LPA and EGF in rat-1 Fibroblasts
56. Growth Factor-Induced Activation of a Kinase Activity which Causes Regulatory Phosphorylation of p42/Microtubule-Associated Protein Kinase
57. Phospholipase C-γl and Phosphoatidylinositol 3-Kinase are the Downstream Mediators of the PDGF Receptors Mitogenic Signal
58. Ras Mediates Nerve Growth Factor Receptor Modulation of Three Signal-Transducing Protein Kinases: MAP Kinase, Raf-1, and Rsk
59. Inhibition of NIH3T3 Cell Proliferation by a Mutant Ras Protein with Preferential Affinity for GDP
60. Raf-1 Protein Kinase is Required for Growth of Induced NIH/3T3 Cells
61. ras-Directed Activation of Extracellular Signal-Regulated Kinase 2 and Phosphorylation of mSos Nucleotide Exchange Factor
62. Inhibition by cAMP of Ras-Dependent Activation of Raf
63. Protein Kinase A Antagonizes Platelet-Derived Growth Factor-Induced Signaling by Mitogen-Activated Protein Kinase in Human Arterial Smooth Muscle Cells
64. Increasing cAMP Attenuates Activation of Mitogen-Activated Protein Kinase
65. Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3,5-Monophosphate
66. Ras is Essential for Nerve Growth Factor- and Phorbol Ester-Induced Tyrosine Phosphorylation of MAP Kinases
67. Multiple Agents Rescue PC12 Cells from Serum-Free Cell Death by Translation- and Transcription-Independent Mechanisms
68. The β-PDGF Receptor Induces Neuronal Differentiation of PC12 Cells
69. ras Activity and Consequent Prolonged ERK Activity
70. MAP Kinase is Constitutively Activated in gip2 and Src Transformed Rat 1a Fibroblasts
71. Conditional Transformation of Cells and Rapid Activation of the Mitogen-Activated Protein Kinase Cascade by an Estradiol-Dependent Human Raf-1 Protein Kinase
72. Cyclin D1 is a nuclear protein required for cell cycle progression in G1.
73. l Events and Regulation of Cell Proliferation