메뉴 건너뛰기




Volumn 54, Issue 4, 1994, Pages 1071-1076

In Vitro Generation of Human Cytolytic T-Cells Specific for Peptides Derived from the HER-2/neu Protooncogene Protein

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPITOPE; TUMOR ANTIGEN;

EID: 0028330866     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (160)

References (56)
  • 1
    • 0017102822 scopus 로고
    • Models for syngeneic adoptive chemoimmunotherapy of murine leukemias
    • Fefer, A., Jr., Einstein, A. Cheever, M., and Berenson, J. Models for syngeneic adoptive chemoimmunotherapy of murine leukemias. Ann. NY Acad. Sci., 276: 573-583, 1976.
    • (1976) Ann. NY Acad. Sci. , vol.276 , pp. 573-583
    • Fefer, A.1    Einstein, A.2    Cheever, M.3    Berenson, J.4
  • 2
    • 0022574005 scopus 로고
    • Therapy of murine leukemia with cyclophosphamide and immune Lyt-2+ T cells: cytolytic T cells can mediate eradication of disseminated leukemia
    • Greenberg, P. Therapy of murine leukemia with cyclophosphamide and immune Lyt-2+ T cells: cytolytic T cells can mediate eradication of disseminated leukemia. J. Immunol., 136: 1917-1922, 1986.
    • (1986) J. Immunol. , vol.136 , pp. 1917-1922
    • Greenberg, P.1
  • 3
    • 0021826670 scopus 로고
    • Therapy of disseminated murine leukemia with cyclophosphamide and immune Lyt-+2-T cells: tumor eradication does not require participation of cytotoxic T cells
    • Greenberg, P., Kern, D., and Cheever, M. Therapy of disseminated murine leukemia with cyclophosphamide and immune Lyt-+2-T cells: tumor eradication does not require participation of cytotoxic T cells. J. Exp. Med., 161: 1122-1134, 1985.
    • (1985) J. Exp. Med. , vol.161 , pp. 1122-1134
    • Greenberg, P.1    Kern, D.2    Cheever, M.3
  • 4
    • 0021888316 scopus 로고
    • Adoptive immunotherapy of newly induced murine sarcomas
    • Shu, S., and Rosenberg, R. Adoptive immunotherapy of newly induced murine sarcomas. Cancer Res., 45: 1657-1662, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 1657-1662
    • Shu, S.1    Rosenberg, R.2
  • 5
    • 0018934336 scopus 로고
    • Specificity of adoptive chemoimmunotherapy of established syngeneic tumors
    • Cheever, M., Greenberg, P., and Fefer, A. Specificity of adoptive chemoimmunotherapy of established syngeneic tumors. J. Immunol., 125: 711-714, 1980.
    • (1980) J. Immunol. , vol.125 , pp. 711-714
    • Cheever, M.1    Greenberg, P.2    Fefer, A.3
  • 6
    • 0019421204 scopus 로고
    • Specific adoptive therapy of established leukemia with syngeneic lymphocytes sequentially immunized in vivo and in vitro and nonspecifically expanded by culture with interleukin-2
    • Cheever, M., Greenberg, P., and Fefer, A. Specific adoptive therapy of established leukemia with syngeneic lymphocytes sequentially immunized in vivo and in vitro and nonspecifically expanded by culture with interleukin-2. J. Immunol., 726: 1318-1322, 1981.
    • (1981) J. Immunol. , vol.726 , pp. 1318-1322
    • Cheever, M.1    Greenberg, P.2    Fefer, A.3
  • 7
    • 0026648439 scopus 로고
    • Restoration of viral immunity in immunocompromised humans by the adoptive transfer of T cell clones
    • Riddell, S., Watanabe, K., Goodrich, J., Li, C., Agha, M., and Greenberg, P. Restoration of viral immunity in immunocompromised humans by the adoptive transfer of T cell clones. Science (Washington DC), 257: 238-241, 1992.
    • (1992) Science (Washington DC) , vol.257 , pp. 238-241
    • Riddell, S.1    Watanabe, K.2    Goodrich, J.3    Li, C.4    Agha, M.5    Greenberg, P.6
  • 8
    • 0025834851 scopus 로고
    • Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells
    • Jerome, K., Barnd, D., Bendt, K., Boyer, C., Taylor-Papdimitriou, J., McKenzie, I., Bast, R., Jr., and Finn, O. Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells. Cancer Res., 51: 2908-2916, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 2908-2916
    • Jerome, K.1    Barnd, D.2    Bendt, K.3    Boyer, C.4    Taylor-Papdimitriou, J.5    McKenzie, I.6    Bast, R.7    Finn, O.8
  • 9
    • 0026532365 scopus 로고
    • Toward a genetic analysis of tumor rejection antigens
    • Boon, T. Toward a genetic analysis of tumor rejection antigens. Adv. Cancer Res., 58: 177-210, 1992.
    • (1992) Adv. Cancer Res. , vol.58 , pp. 177-210
    • Boon, T.1
  • 10
    • 0026662284 scopus 로고
    • T cell recognition of oncogene products: a new strategy for immunotherapy
    • Ioannides, C., loannides, M., and O'Brian, C. T cell recognition of oncogene products: a new strategy for immunotherapy. Mol. Carcinog., 6: 77-82, 1992.
    • (1992) Mol. Carcinog. , vol.6 , pp. 77-82
    • Ioannides, C.1    loannides, M.2    O'Brian, C.3
  • 12
    • 0025882042 scopus 로고
    • T cell recognition of transforming proteins encoded by mutated ras proto-oncogenes
    • Peace, D., Chen, W., Nelson, H., and Cheever, M. T cell recognition of transforming proteins encoded by mutated ras proto-oncogenes. J. Immunol., 146: 2059-2065, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 2059-2065
    • Peace, D.1    Chen, W.2    Nelson, H.3    Cheever, M.4
  • 15
    • 0025177290 scopus 로고
    • Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-s protein overexpression in primary breast cancer
    • Paik, S., Hazan, R., Fisher, E., Sass, R., Fisher, B., Redmond, C., Schlessinger, J., Lippman, M., and King, C. Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-s protein overexpression in primary breast cancer. J. Clin. Oncol., 8: 103-112, 1990.
    • (1990) J. Clin. Oncol. , vol.8 , pp. 103-112
    • Paik, S.1    Hazan, R.2    Fisher, E.3    Sass, R.4    Fisher, B.5    Redmond, C.6    Schlessinger, J.7    Lippman, M.8    King, C.9
  • 16
    • 0026650016 scopus 로고
    • Prognostic significance of HER-2 oncoprotein expression in breast cancer: a 30-year follow-up
    • Toikkanen, S., Helin, H., Isola, J., and Joensuu, H. Prognostic significance of HER-2 oncoprotein expression in breast cancer: a 30-year follow-up. J. Clin. Oncol., 10: 1044-1048, 1992.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1044-1048
    • Toikkanen, S.1    Helin, H.2    Isola, J.3    Joensuu, H.4
  • 17
    • 0026793986 scopus 로고
    • Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer
    • Allred, D., Clark, G., Molina, R., Tandon, A., Schnitt, S., Gilchrist, K., Osborne, C., Tormey, D., and McGuire, W. Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer. Hum. Pathol., 23: 974-979, 1992.
    • (1992) Hum. Pathol. , vol.23 , pp. 974-979
    • Allred, D.1    Clark, G.2    Molina, R.3    Tandon, A.4    Schnitt, S.5    Gilchrist, K.6    Osborne, C.7    Tormey, D.8    McGuire, W.9
  • 18
    • 0025250643 scopus 로고
    • The recognition of a viral antigenic moiety by class I MHC-restricted cytolytic T lymphocytes is limited by the availability of the endogenously processed antigen
    • Milligan, G., Morrison, L., Gorka, J., Braciale, V., and Braciale, T. The recognition of a viral antigenic moiety by class I MHC-restricted cytolytic T lymphocytes is limited by the availability of the endogenously processed antigen. J. Immunol., 145: 3188-3193, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 3188-3193
    • Milligan, G.1    Morrison, L.2    Gorka, J.3    Braciale, V.4    Braciale, T.5
  • 20
    • 0025155540 scopus 로고
    • c-erbB-2 expression in breast cancer detected by immunoblotting and immunohistochemistry
    • Kerns, B., Pence, J., Huper, G., Kinney, R., and Iglehart, J. c-erbB-2 expression in breast cancer detected by immunoblotting and immunohistochemistry. J. Histochem. Cytochem., 38: 1823-1830, 1990.
    • (1990) J. Histochem. Cytochem. , vol.38 , pp. 1823-1830
    • Kerns, B.1    Pence, J.2    Huper, G.3    Kinney, R.4    Iglehart, J.5
  • 21
    • 0025359146 scopus 로고
    • Expression of HER-2/neu proto-onco-gene in normal human adult and fetal tissues
    • Press, M., Cordon-Cardo, C., and Slamon, D. Expression of HER-2/neu proto-onco-gene in normal human adult and fetal tissues. Oncogene, 5: 953-962, 1990.
    • (1990) Oncogene , vol.5 , pp. 953-962
    • Press, M.1    Cordon-Cardo, C.2    Slamon, D.3
  • 22
    • 0025228906 scopus 로고
    • Expression of the p. 85 encoded by HER2 oncogene in normal and transformed human tissues
    • Natali, P., Nicotra, M., Bigotti, A., Venturo, I., Slamon, D., Fendly, B., and Ullrich, A. Expression of the p. 85 encoded by HER2 oncogene in normal and transformed human tissues. Int. J. Cancer, 45: 457-461, 1990.
    • (1990) Int. J. Cancer , vol.45 , pp. 457-461
    • Natali, P.1    Nicotra, M.2    Bigotti, A.3    Venturo, I.4    Slamon, D.5    Fendly, B.6    Ullrich, A.7
  • 25
    • 0025855156 scopus 로고
    • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
    • Falk, K., Rötzschke, O., Stevanovic, S., Jung, G., and Rammensee, H.G. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature (Lond.), 351: 290-296, 1991.
    • (1991) Nature (Lond.) , vol.351 , pp. 290-296
    • Falk, K.1    Rötzschke, O.2    Stevanovic, S.3    Jung, G.4    Rammensee, H.G.5
  • 26
    • 0026657070 scopus 로고
    • In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides
    • Zhou, X., Berg, L., Motal, U., and Jondal, M. In vivo primary induction of virus-specific CTL by immunization with 9-mer synthetic peptides. J. Immunol. Methods, 153: 193-200, 1992.
    • (1992) J. Immunol. Methods , vol.153 , pp. 193-200
    • Zhou, X.1    Berg, L.2    Motal, U.3    Jondal, M.4
  • 27
    • 0024338186 scopus 로고
    • Induction of class I MHC-restricted, peptide-specific cytolytic T lymphocytes by peptide priming in vivo
    • Ishioka, G., Colon, S., Miles, C., Grey, H., and Chesnut, R. Induction of class I MHC-restricted, peptide-specific cytolytic T lymphocytes by peptide priming in vivo. J. Immunol., 143: 1094-1100, 1989.
    • (1989) J. Immunol. , vol.143 , pp. 1094-1100
    • Ishioka, G.1    Colon, S.2    Miles, C.3    Grey, H.4    Chesnut, R.5
  • 31
    • 0026566332 scopus 로고
    • The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation
    • Riberdy, J., and Cresswell, P. The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation. J. Immunol., 148: 2586-2590, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 2586-2590
    • Riberdy, J.1    Cresswell, P.2
  • 32
    • 0025688348 scopus 로고
    • Sequences encoded in the class II region of the MHC related to the ABC superfamily of transporters
    • Trowsdale, J., Hanson, I., Mockridge, I., Beck, S., Townsend, A., and Kelly, A. Sequences encoded in the class II region of the MHC related to the ABC superfamily of transporters. Nature (Lond.), 348: 741-744, 1990.
    • (1990) Nature (Lond.) , vol.348 , pp. 741-744
    • Trowsdale, J.1    Hanson, I.2    Mockridge, I.3    Beck, S.4    Townsend, A.5    Kelly, A.6
  • 33
    • 0025604835 scopus 로고
    • A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway
    • Spies, T., Bresnahan, M., Bahram, S., Arnold, D., Blanck, G., Mellins, E., Pious, D., and DeMars, R. A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. Nature (Lond.), 348: 744-747, 1990.
    • (1990) Nature (Lond.) , vol.348 , pp. 744-747
    • Spies, T.1    Bresnahan, M.2    Bahram, S.3    Arnold, D.4    Blanck, G.5    Mellins, E.6    Pious, D.7    DeMars, R.8
  • 36
    • 0027424944 scopus 로고
    • Human leukocyte antigen-A2.1 restricted candidate cytotoxic T lymphocyte epitopes of human papillomavirus type 16 E6 and E7 proteins identified by using the processing-defective human cell line T2
    • Kast, W., Brandt, R., Drijfhout, J., and Melief, C. Human leukocyte antigen-A2.1 restricted candidate cytotoxic T lymphocyte epitopes of human papillomavirus type 16 E6 and E7 proteins identified by using the processing-defective human cell line T2. J. Immunother., 14: 115-120, 1993.
    • (1993) J. Immunother. , vol.14 , pp. 115-120
    • Kast, W.1    Brandt, R.2    Drijfhout, J.3    Melief, C.4
  • 38
    • 0022483534 scopus 로고
    • The epitopes of influenza nucleoproteins recognized by cytotoxic lymphocytes can be defined with short synthetic peptides
    • Townsend, A., Rothbard, J., Frances, M., Gotch, G., Bahadur, J., Wrath, D., and McMichael, A. The epitopes of influenza nucleoproteins recognized by cytotoxic lymphocytes can be defined with short synthetic peptides. Cell, 44: 959-968, 1986.
    • (1986) Cell , vol.44 , pp. 959-968
    • Townsend, A.1    Rothbard, J.2    Frances, M.3    Gotch, G.4    Bahadur, J.5    Wrath, D.6    McMichael, A.7
  • 39
    • 0026632418 scopus 로고
    • A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein
    • Udaka, K., Tsomides, T., and Eisen, H. A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein. Cell, 69: 989, 1992.
    • (1992) Cell , vol.69 , pp. 989
    • Udaka, K.1    Tsomides, T.2    Eisen, H.3
  • 40
    • 0025287307 scopus 로고
    • Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide
    • Aichele, P., Hengartner, H., Zinkernagel, R., and Schultz, M. Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide. J. Exp. Med., 171: 1815-1820, 1990.
    • (1990) J. Exp. Med. , vol.171 , pp. 1815-1820
    • Aichele, P.1    Hengartner, H.2    Zinkernagel, R.3    Schultz, M.4
  • 41
    • 0026486222 scopus 로고
    • Vaccination of rhesus monkeys with synthetic peptide in a fusogenic proteoliposome elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes
    • Miller, M., Gould-Fogerite, S., Shen, L., Woods, R., Koenig, S., Mannino, R., and Letvin, N. Vaccination of rhesus monkeys with synthetic peptide in a fusogenic proteoliposome elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes. J. Exp. Med, 176: 1739-1744, 1992.
    • (1992) J. Exp. Med , vol.176 , pp. 1739-1744
    • Miller, M.1    Gould-Fogerite, S.2    Shen, L.3    Woods, R.4    Koenig, S.5    Mannino, R.6    Letvin, N.7
  • 42
    • 0025310910 scopus 로고
    • Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs
    • Takahashi, H., Toshiyuki, T., Morein, B., Putney, S., Germain, R., and Berzofsky, J. Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs. Nature (Lond.), 344: 873-875, 1990.
    • (1990) Nature (Lond.) , vol.344 , pp. 873-875
    • Takahashi, H.1    Toshiyuki, T.2    Morein, B.3    Putney, S.4    Germain, R.5    Berzofsky, J.6
  • 43
    • 0026770830 scopus 로고
    • Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120
    • Sastry, K., Nehete, P., Venkatnarayanan, S., Morkowski, J., Platsoucas, C., and Arlinghaus, R. Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120. Virology, 188: 502-509, 1992.
    • (1992) Virology , vol.188 , pp. 502-509
    • Sastry, K.1    Nehete, P.2    Venkatnarayanan, S.3    Morkowski, J.4    Platsoucas, C.5    Arlinghaus, R.6
  • 45
    • 0026093754 scopus 로고
    • Priming of anti-human immunodeficiency virus (HIV) CD8+ cytotoxic T cells in vivo by carrier-free HIV synthetic peptides
    • Hart, M., Weinhold, K., Scearce, R., Washburn, E., Clark, C., Palker, T., and Haynes, B. Priming of anti-human immunodeficiency virus (HIV) CD8+ cytotoxic T cells in vivo by carrier-free HIV synthetic peptides. Proc. Natl. Acad. Sci. USA, 88: 9448-9452, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9448-9452
    • Hart, M.1    Weinhold, K.2    Scearce, R.3    Washburn, E.4    Clark, C.5    Palker, T.6    Haynes, B.7
  • 46
    • 0023685463 scopus 로고
    • HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides
    • Nixon, D., Townsend, A., Elvin, J., Rizza, C., Gallwey, J., and McMichael, A. HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides. Nature (Lond.), 336: 484-487, 1988.
    • (1988) Nature (Lond.) , vol.336 , pp. 484-487
    • Nixon, D.1    Townsend, A.2    Elvin, J.3    Rizza, C.4    Gallwey, J.5    McMichael, A.6
  • 47
    • 0026718096 scopus 로고
    • Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1
    • Hosmalin, A., Kumar, S., Barnd, D., Houghten, R., Smith, G., Hughes, S., and Berzofsky, J. Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1. J. Immunol, 149: 1311-1318, 1992.
    • (1992) J. Immunol , vol.149 , pp. 1311-1318
    • Hosmalin, A.1    Kumar, S.2    Barnd, D.3    Houghten, R.4    Smith, G.5    Hughes, S.6    Berzofsky, J.7
  • 48
    • 0025145361 scopus 로고
    • In vitro human cytotoxic T cell responses against influenza A virus can be induced and selected by synthetic peptides
    • Martinon, F., Gomard, E., Hannoun, C., and Levy, J. In vitro human cytotoxic T cell responses against influenza A virus can be induced and selected by synthetic peptides. Eur. J. Immunol, 20: 2171-2176, 1990.
    • (1990) Eur. J. Immunol , vol.20 , pp. 2171-2176
    • Martinon, F.1    Gomard, E.2    Hannoun, C.3    Levy, J.4
  • 49
    • 84970068096 scopus 로고
    • Lysis of ras oncogene-transformed cells by cytotoxic T lymphocytes specific for the oncogenic p. 1ras protein
    • in press
    • Peace, D., Smith, J., Chen, W., You, S.G., Cosand, W., Blake, J., and Cheever, M. Lysis of ras oncogene-transformed cells by cytotoxic T lymphocytes specific for the oncogenic p. 1ras protein. J. Exp. Med, in press, 1994.
    • (1994) J. Exp. Med
    • Peace, D.1    Smith, J.2    Chen, W.3    You, S.G.4    Cosand, W.5    Blake, J.6    Cheever, M.7
  • 50
    • 0025873357 scopus 로고
    • The binding affinity and dissociation rates of peptides for class I major histocompatibility complex molecules
    • Cerundolo, V., Elliott, T., Elvin, J., Bastin, J., Rammensee, H., and Townsend, A. The binding affinity and dissociation rates of peptides for class I major histocompatibility complex molecules. Eur. J. Immunol, 21: 2069-2075, 1991.
    • (1991) Eur. J. Immunol , vol.21 , pp. 2069-2075
    • Cerundolo, V.1    Elliott, T.2    Elvin, J.3    Bastin, J.4    Rammensee, H.5    Townsend, A.6
  • 51
    • 0026770269 scopus 로고
    • Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in human papilloma virus
    • Stauss, H.J., Davies, H., Sadovnikova, E., Chain, B., Horowitz, N., and Sinclair, C. Induction of cytotoxic T lymphocytes with peptides in vitro: identification of candidate T-cell epitopes in human papilloma virus. Proc. Natl. Acad. Sci. USA, 89: 7871-7875, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7871-7875
    • Stauss, H.J.1    Davies, H.2    Sadovnikova, E.3    Chain, B.4    Horowitz, N.5    Sinclair, C.6
  • 52
    • 0023772130 scopus 로고
    • Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptides
    • Carbone, F., Moore, M., Sheil, J., and Bevan, M. Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptides. J. Exp. Med, 167: 1767-1779, 1988.
    • (1988) J. Exp. Med , vol.167 , pp. 1767-1779
    • Carbone, F.1    Moore, M.2    Sheil, J.3    Bevan, M.4
  • 53
    • 0026513529 scopus 로고
    • The priming of cytotoxic T-cell precursors is strictly helper T cell-dependent
    • Lin, Y., Langman, R., and Cohn, M. The priming of cytotoxic T-cell precursors is strictly helper T cell-dependent. Scand. J. Immunol, 35: 621-626, 1992.
    • (1992) Scand. J. Immunol , vol.35 , pp. 621-626
    • Lin, Y.1    Langman, R.2    Cohn, M.3
  • 54
    • 0026739624 scopus 로고
    • T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides
    • Widmann, C., Romero, P., Maryanski, J., Corradin, G., and Valmori, D. T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides. J. Immunol. Methods, 155: 95-99, 1992.
    • (1992) J. Immunol. Methods , vol.155 , pp. 95-99
    • Widmann, C.1    Romero, P.2    Maryanski, J.3    Corradin, G.4    Valmori, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.