Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support

Journal of Clinical Oncology

Volumn 12, Issue 5, 1994, Pages 1005-1011

  Gilbert, Colleen ^a   Meisenberg, Barry ^a   Vredenburgh, James ^a   Ross, Maureen ^a   Hussein, Atif ^a   Perfect, John ^a   Peters, William P ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AMPHOTERICIN B; CIPROFLOXACIN; MONOCLONAL ANTIBODY; RIFAMPICIN; TOBRAMYCIN; VANCOMYCIN;

ADULT; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BACTEREMIA; BONE MARROW TRANSPLANTATION; BREAST CANCER; CANCER CHEMOTHERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; FEVER; FUNGEMIA; HUMAN; INFECTION PREVENTION; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; NAUSEA; NEUTROPENIA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STEM CELL; VOMITING;

EID: 0028328638     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1994.12.5.1005     Document Type: Article

References (25)

1. Cheson BD, Lacerna L, Leyland-Jones, et al: Autologous bone marrow transplantation: Current status and future directions. Ann Intern Med 110:51-65, 1989
2. Gulati SC, Yahalom J, Portlock CS: Autologous bone marrow transplantation. Curr Probl Cancer 15:51-57, 1991
3. Brandt SJ, Peters WP, Atwater SL, et al: Effect of recombinant granulocyte-macrophage colony stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone marrow transplantation. N Engl J Med 318:869-876, 1988
4. Peters WP, Ross M, Vredenburgh J, et al: Role of cytokines in autologous bone marrow transplantation. Hematol Oncol Clin North Am 7:737-747, 1993
5. Mertelsmann R, Hermann F, Hecht T, et al: Hematopoietic growth factors in bone marrow transplantation. Bone Marrow Transplant 6:73-77, 1990
6. Peters WP, Kurtzberg J, Rosner G, et al: Comparative effects of G-CSF and GM-CSF on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. Blood 81:1709-1719, 1993
7. Young LS: Antimicrobial prophylaxis in the neutropenic host: Lessons of the past and perspectives for the future. Eur J Clin Microbiol Infect Dis 7:93-97, 1988
8. Karp JE, Merz WG, Hendrickson C, et al: Oral norfloxacin for prevention of gram-negative bacterial infections in patients with acute leukemia and granulocytopenia. Ann Intern Med 106:1-7, 1987
9. Dekker AW, Rozenberg-Arska M, Verhoff J: Infection prophylaxis in acute leukemia: A comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin. Ann Intern Med 107:7-12, 1987
10. Kern W, Kurrle E: Ofloxacin versus trimethoprim-sulfamethoxazole for prevention of infection in patients with acute leukemia and granulocytopenia. Infection 19:73-80, 1991
11. Wimperis JZ, Baglin TP, Marcus RE, et al: An assessment of the efficacy of antimicrobial prophylaxis in bone marrow autografts. Bone Marrow Transplant 8:363-367, 1991
12. De Pauw BE, Donnelly JP, De Witte T, et al: Options and limitations of long term ciprofloxacin as antibacterial prophylaxis in allogeneic bone marrow transplant recipients. Bone Marrow Transplant 5:179-182, 1990
13. Hughes WT, Armstrong D, Bodey GP, et al: Guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. J Infect Dis 161:381-396, 1990
14. Gilbert DN: Once daily aminoglycoside therapy. Antimicrob Agents Chemother 35:399-405, 1991
15. Zhanel GG, Hoban DJ, Harding GKM: The post antibiotic effect: A review of in vitro and in vivo data. Ann Pharmacother 25:153-163, 1991
16. Peters WP, Shpall EJ, Jones RB, et al: High-dose combination alkylating agents with bone marrow support as initial treatment for metastatic breast cancer. J Clin Oncol 6:1368-1376, 1988
17. Shpall J, Jones RB, Bast R, et al: 4-Hydroperoxycyclophosphamide (4-HC) purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high dose chemotherapy and autologous marrow support: A phase I trial. J Clin Oncol 9:85-93, 1991
18. Shpall J, Bast R, Joines WT, et al: Immunomagnectic purging of breast cancer from bone marrow for autologous transplantation. Bone Marrow Transplant 7:145-151, 1991
19. Shpall J, Bast R, Johnston C, et al: Combined purging approaches in autologous transplantation, in Gee AP (ed): In Vitro Bone Marrow Processing. Boca Raton, FL, CRC, 1991, pp. 307-328
20. Attal M, Schlaifer, Rubie H, et al: Prevention of gram-positive infections after bone marrow transplantation by systemic vancomycin: A prospective randomized trial. J Clin Oncol 9:865-870, 1991
21. Silver LL, Bostiam KA: Discovery and development of new antibiotics: The problem of antibiotic resistance. Antimicrob Agents Chemother 37:377-383, 1993
22. Levinson ME: New dosing regimens for aminoglycoside antibiotics. Ann Intern Med 117:693-694, 1992
23. The Internation Antimicrobial Therapy Cooperative Group of the Curopean Organization for Research and Treatment of Cancer: Efficacy and toxicity of single daily doses of amikacin and ceftriaxone versus multiple daily doses of amikacin and ceftazidime for infection in patients with cancer and granulocytopenia. Ann Intern Med 119:584-593, 1991
24. Rubenstein EB, Rolston K, Benjamin RS, et al: Outpatient treatment of febrile episodes in low-risk neutropenic patients with cancer. Cancer 71:3640-3646, 1993
25. Peters WP, Ross M, Vredenburgh J, et al: The use of intensive clinic support to permit outpatient autologous bone marrow transplantation for breast cancer. Semin Oncology (in press)