Functional switching of macrophage responses to tumor necrosis factor-α (TNFα) by interferons: Implications for the pleiotropic activities of TNFα

Journal of Clinical Investigation

Volumn 93, Issue 4, 1994, Pages 1661-1669

  Lake, Fiona R ^a,e   Noble, Paul W ^b,f   Henson, Peter M ^a   Riches, David W H ^a,b,c,d  

^a Natl Jewish Ctr Immunol Resp M ^*

^b Department of Medicine ^*

^c UNIVERSITY OF COLORADO   (United States)

^d NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^f JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

inflammation; insulin like growth factor 1; interferons; macrophages; TNF receptors; tumor necrosis factor

Indexed keywords

BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYALURONIC ACID; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SOMATOMEDIN C; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; INFLAMMATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RNA ANALYSIS;

EID: 0028327239     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI117148     Document Type: Article

References (63)

1. Tracey, K. J., H. Vlassara, and A. Cerami. 1989. Cachectin/tumour necrosis factor. Lancet. i:1122-6.
2. Fiers, W. 1991. Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level. FEBS (Fed. Eur. Biochem. Soc.) Lett. 285:199-212.
3. Kim, S. J., W. G. Wierda, and Y. B. Kim. 1991. Immobilized IgG immune complex induces secretion of tumor necrosis factor-α by porcine alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 5:249-255.
4. Noble, P. W., F. R. Lake, P. M. Henson, and D. W. H. Riches. 1993. Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-α-dependent mechanism in murine macrophages. J. Clin. Invest. 91:2368-2377.
5. Beutler, B., and A. Cerami. 1988. Tumor necrosis, cachexia, shock and inflammation: a common mediator. Annu. Rev. Biochem. 57:505-518.
6. Piguet, P. F., G. E. Grau, M. A. Collart, P. Vassalli, and Y. Kapanci. 1989. Pneumopathies of the graft-versus-host reaction. Alveolitis associated with an increased level of tumor necrosis factor mRNA and chronic interstitial pneumonitis. Lab. Invest. 61:37-45.
7. Nestel, F. P., K. S. Price, T. A. Seemayer, and W. S. Lapp. 1992. Macrophage priming and lipopolysaccharide-triggered release of tumor necrosis factor α during graft-versus-host disease. J. Exp. Med. 175:405-413.
8. Michishita, M., Y. Yoshida, H. Uchino, and K. Nagata. 1990. Induction of tumor necrosis factor-α and its receptors during differentiation in myeloid leukemic cells along the monocytic pathway. J. Biol. Chem. 265:8751-8759.
9. Witsell, A. L., and L. B. Schook. 1992. Tumor necrosis factor α is an autocrine growth regulator during macrophage differentiation. Proc. Natl. Acad. Sci. USA. 89:4754-4758.
10. Chen, L., Y. Suzuki, and E. F. Wheelock. 1987. Interferon-γ synergizes with tumor necrosis factor and with interleukin 1 and requires the presence of both monokines to induce antitumor cytotoxic activity in macrophages. J. Immunol. 139:4096-4101.
11. Hori, K., E. Mihich, and M. J. Ehrke. 1989. Role of tumor necrosis factor and interleukin 1 in γ-interferon-promoted activation of mouse tumoricidal macrophages. Cancer Res. 49:2606-2614.
12. Philip, R., and L. B. Epstein. 1986. Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, gamma-interferon and interleukin-1. Nature (Lond.). 323:86-9.
13. Vassalli, P. 1992. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10:411-452.
14. Mace, K. F., M. J. Ehrke, K. Hori, D. L. Maccubbin, and E. Mihich. 1988. Role of tumor necrosis factor in macrophage activation and tumoricidal activity. Cancer Res. 48:5427-32.
15. Hohmann, H. P., R. Remy, M. Brockhaus, and A. P. G. M. van Loon. 1989. Two different cell types have different major receptors for human tumor necrosis factor (TNFα). J. Biol. Chem. 264:14927-14934.
16. Brockhaus, M., H. Schoenfeld, E. Scheager, W. Hunziker, W. Lesslauer, and H. Loetscher. 1990. Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. Proc. Natl. Acad. Sci. USA. 87:3127-3131.
17. Smith, C. A., T. Davis, D. Anderson, L. Solam, L. P. Beckmann, R. Jerzy, S. K. Dower, D. Cosman, and R. G. Goodwin. 1990. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science (Wash. DC). 248:1019-1023.
18. Tartaglia, L. A., R. F. Weber, I. S. Figari, C. Reynolds, M. A. Palladino, and D. V. Goeddel. 1991. The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc. Natl. Acad. Sci. USA. 88:9292-9296.
19. Espevik, T., M. Brockhaus, H. Loetscher, U. Nonstad, and R. Shalaby. 1990. Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor. J. Exp. Med. 171:415-26.
20. Schall, T. J., M. Lewis, K. J. Koller, A. Lee, G. C. Rice, G. H. Wong, T. Gatanaga, G. A. Granger, R. Lentz, H. Raab, W. J. Kohr, and D. V. Goeddel. 1990. Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell. 61:361-70.
21. Lewis, M., L. A. Tartaglia, A. Lee, G. L. Bennett, G. C. Rice, G. H. W. Wong, E. Y. Chen, and D. V. Goeddel. 1991. Cloning and expression of two cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc. Natl. Acad. Sci. USA. 88:2830-2834.
22. Loetscher, H., Y. C. Pan, H. W. Lahm, R. Gentz, M. Brockhaus, H. Tabuchi, and W. Lesslauer. 1990. Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor. Cell. 61:351-9.
23. Engelmann, H., H. Holtman, C. Brakebush, D. Novich, and D. Wallach. 1990. Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. J. Biol. Chem. 265:1531-1536.
24. Engelmann, H., H. Holtman, C. Brakebush, Y. Shemer-Avni, I. Sarov, Y. Nophar, E. Hadas, O. Leitner, and D. Wallach. 1990. Antibodies to a soluble form of tumor necrosis factor (TNF) have TNF-like activity. J. Biol. Chem. 265:14497-14504.
25. Shalaby, M. R., W. W. Laegreid, A. J. Ammann, and H. D. Liggitt. 1989. Tumor necrosis factor-alpha-associated uterine endothelial injury in vivo. Influence of dietary fat. Lab. Invest. 61:564-70.
26. Vandenabeele, P., W. Declercq, D. Vercammen, M. Van de Craen, J. Grooten, H. Loetscher, M. Brockhaus, W. Lesslauer, and W. Fiers. 1992. Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma. J. Exp. Med. 176:1015-1024.
27. Riches, D. W. H., P. M. Henson, L. K. Remigio, J. F. Catterall, and R. C. Strunk. 1988. Differential regulation of gene expression during macrophage activation with a polyribonucleotide. The role of endogenously derived IFN. J. Immunol. 141:180-8.
28. Riches, D. W. H., and G. A. Underwood. 1991. Expression of IFNβ during the triggering phase of macrophage cytocidal activation. Evidence for an autocrine/paracrine role in the regulation of this state. J. Biol. Chem. 266:24785-24792.
29. Rappolee, D. A., and Z. Werb. 1990. mRNA phenotyping for studying gene expression in small numbers of cells: platelet-derived growth factor and other growth factors in wound-derived macrophages. Am. J. Respir. Cell Mol. Biol. 2:3-10.
30. Rom, W. N., P. Basset, G. A. Fells, T. Nukiwa, B. C. Trapnell, and R. G. Crystal. 1988. Alveolar macrophages release an insulin-like growth factor 1-type molecule. J. Clin. Invest. 82:1685-1693.
31. Pace, J. L., S. W. Russell, P. A. LeBlanc, and D. M. Murasko. 1985. Comparative effects of various classes of mouse interferons on macrophage activation for tumor cell killing. J. Immunol. 134:977-81.
32. Stewart, C. C. 1981. Murine mononuclear phagocytes from bone marrow. In Methods for Studying Mononuclear Phagocytes. D. O. Adams, P. J. Edelson, and H. Koren, editors. Academic Press. New York. 5-20.
33. Riches, D. W. H., and P. M. Henson. 1986. Bacterial lipopolysaccharide suppresses the production of catalytically active lysosomal acid hydrolases in human macrophages. J. Cell Biol. 102:1606-14.
34. Cole, F. S., H. S. Auerbach, G. Goldberger, and H. R. Colten. 1985. Tissue specific pretranslational regulation of complement production in human mononuclear phagocytes. J. Immunol. 134:2610-2616.
35. Roberts, B. E., and B. M. Paterson. 1973. Effect of translation of tobacco mosaic virus RNA and rabbit globin 9S RNA in a cell-free system from commercial wheat germ. Proc. Natl. Acad. Sci. USA. 70:2330-2334.
36. Chirgwin, J. M., R. J. Przbyla, R. J. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriches in ribonuclease. Biochemistry. 18:5294-5299.
37. Thomas, P. 1980. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA. 77:5201-5206.
38. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
39. Feinberg, A. P., and B. Vogelstein. 1984. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Addendum. Anal. Biochem. 137:266-7.
40. Ruff, M. R., and G. E. Gifford. 1981. Rabbit tumor necrosis factor: mechanism of action. Infect. Immunol. 31:380-385.
41. Remels, L., L. Fransen, K. Huygen, and B. P. De. 1990. PolyI:C activated macrophages are tumoricidal for TNF-alpha-resistant 3LL tumor cells. J. Immunol. 144:4477-86.
42. Russell, S. W., W. F. Doe, and A. T. McIntosh. 1977. Functional characterization of a stable, noncytolytic stage of macrophage activation in tumors. J. Exp. Med. 146:1511-1520.
43. Torres, B. A., and H. M. Johnson. 1985. Lipopolysaccharide and polyribonucleotide activation of macrophages: implications for a natural triggering signal in tumor cell killing. Biochem. Biophys. Res. Commun. 131:395-401.
44. Nagaoka, I., B. C. Trapnell, and R. G. Crystal. 1990. Regulation of insulin-like growth factor 1 gene expression in the human macrophage-like cell line U937. J. Clin. Invest. 85:448-455.
45. Schutze, S., P. Scheurich, C. Schluter, U. Ucer, K. Pfizenmaier, and M. Kronke. 1988. Tumor necrosis factor-induced changes of gene expression in U937 cells. Differentiation-dependent plasticity of the responsive state. J. Immunol. 140:3000-5.
46. Imamura, K., D. Spriggs, and D. Kufe. 1987. Expression of tumor necrosis factor receptors on human monocytes and internalization of receptor bound ligand. J. Immunol. 139:2989-92.
47. Smith, R. A., M. Kirstein, W. Fiers, and C. Baglioni. 1986. Species specificity of human and murine tumor necrosis factor. A comparative study of tumor necrosis factor receptors. J. Biol. Chem. 261:14871-4.
48. Tartaglia, L. A., and D. V. Goeddel. 1992. Two TNF receptors. Immunol. Today. 13:151-153.
49. Schutze, S., D. Berkovic, O. Tomsing, C. Unger, and M. Kronke. 1991. Tumor necrosis factor induces rapid production of 1́2́diacylglycerol by a phosphatidylcholine-specific phospholiase C. J. Exp. Med. 174:975-988.
50. Lake, F. R., E. C. Dempsey, J. D. Spahn, and D. W. H. Riches. 1994. Involvement of protein kinase C in macrophage activation by poly(I:C). Am. J. Physiol. 266:C134-C142.
51. Hibino, Y., C. S. Kumar, T. M. Mariano, D. Lai, and S. Pestka. 1992. Chimeric interferon-γ receptors demonstrate that an accessory factor required for activity interacts with the extracellular domain. J. Biol. Chem. 267:3741-3749.
52. Kirstein, M., C. Aston, R. Hintz, and H. Vlassara. 1992. Receptor-specific induction of insulin-like growth factor 1 in human monocytes by advanced glycosylation end products-modified proteins. J. Clin. Invest. 90:439-446.
53. Tsujimoto, M., R. Feinman, and J. Vilcek. 1986. Differential effects of type I IFN and IFN-γ on the binding of tumor necrosis factor to receptors in tow human cell lines. J. Immunol. 137:2272-2276.
54. Ruggiero, V., J. Tavernier, W. Fiers, and C. Baglioni. 1986. Induction of the synthesis of tumor necrosis factor receptors by interferon-γ. J. Immunol. 136:2445-2450.
55. Scheurich, P., G. Kobrich, and K. Pfizenmaier. 1989. Antagonistic control of tumor necrosis factor receptors by protein kinases A and C. J. Exp. Med. 170:947-958.
56. 2+ utilization. Mol. Biol. Cell. 3:335-347.
57. Kelley, J. 1990. Cytokines of the lung. Am. Rev. Respir. Dis. 141:765-788.
58. Borm, P. J. A., N. Palmen, J. J. M. Engelen, and W. A. Buurman. 1988. Spontaneous and stimulated release of tumor necrosis factor-alpha (TNF) from blood monocytes of miners with coal workers pneumoconiosis. Am. Rev. Respir. Dis. 138:1589-1594.
59. Piguet, P. F., M. A. Collart, G. E. Grau, Y. Kapanci, and P. Vassalli. 1989. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J. Exp. Med. 170:655-63.
60. Piguet, P. F., M. A. Collart, G. E. Grau, A. P. Sappino, and P. Vassalli. 1990. Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature (Lond.). 344:245-7.
61. Hyde, D. M., T. S. Henderson, S. N. Giri, N. K. Tyler, and M. Y. Stovall. 1988. Effect of murine gamma interferon on the cellular responses to bleomycin in mice. Exp. Lung Res. 14:687-704.
62. Hyde, D. M., and S. N. Giri. 1990. Polyinosinic-polycytidylic acid, an interferon inducer, ameliorates bleomycin-induced lung fibrosis in mice. Exp. Lung Res. 16:533-546.
63. Prior, C., and P. L. Haslam. 1991. Increased levels of serum interferon-gamma in pulmonary sarcoidosis and relationship with response to corticosteroid therapy. Am. Rev. Respir. Dis. 143:53-60.