Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors

Current Opinion in Cell Biology

Volumn 6, Issue 3, 1994, Pages 415-424

  Karin, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN C FOS; PROTEIN KINASE; TRANSCRIPTION FACTOR;

CELL NUCLEUS; CELL SURFACE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMAL; CELL MEMBRANE; CELL NUCLEUS; HUMAN; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS;

EID: 0028322193     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0955-0674(94)90035-3     Document Type: Article

References (76)

1. Regulating Transcription Factor Activity by Phosphorylation
2. The Regulation of transcription by Phosphorylation
3. Cycle AMP Stimulates Somatostatin Gene Transcription by Phosphorylation of CREB at Serine 133
4. Phosphorylated CREB Binds Specifically to the Nuclear Protein CBP
5. Transcriptional Attenuation Following cAMP Induction Requires PP-1 Mediated Dephosphorylation of CREB
6. Nuclear Protein Phosphatase 2A Dephosphorylates Protein Kinase A-Phosphorylated CREB and Regulates CREB Transcriptional Stimulation
7. The Serum Response Element
8. Casein Kinase II Phosphorylation Increase the Rate of Serum Response Factor-Binding Site Exchange
9. Mutation of Serum Response Factor Phosphorylation Sites and the Mechanism by Which its DNA-Binding Activity Is Increased by Casein Kinase II
10. Identification of Multiple SRF N-Terminal Phosphorylation Sites Affecting DNA Binding Properties
11. Phosphorylation of p62TCF by MAP Kinase Stimulates Ternary Complex Formation at cFos Promoter
12. The SRF Accessory Protein ELK-1 Contains a Growth Factor Regulated Transcription Domain
13. TCF
14. Elk-1 protein domains required for direct and SRF-assisted DNA-binding
15. Elk-1 Domains Responsible for Autonomous DNA Binding SRE: SRF Interaction and Negative Regulation of DNA Binding
16. Functional Analysis of a Growth Factor Responsive Transcriptional Factor Complex
17. c-fos Transcriptional Activation and Repression Correlate Temporally with the Phosphorylation Status of TCE
18. Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.
19. The Mitogen-Activated Protein Kinase Signal Transduction Pathway
20. The Mitogen-Activation Protein Kinase Activator
21. The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product
22. Raf-1 Activates MAP Kinase Kinase
23. Activation of Mitogenic Activated Protein Kinase Kinase by v-raf in NIH3T3 Cells and in Vitro
24. Mammalian ras Interacts Directly with the Serine/Threonine Kinase raf
25. α Activates RAF-1 by Direct Phosphorylation
26. Serum-Induced Translocation of Mitogen-Activated Protein Kinase to the Cell Surface Ruffling Membrane and the Nucleus
27. MKP-1 (3CH134), an Immediate Early Gene Product, Is a Dual Specificity Phosphatase that Dephosphorylates MAP Kinase in Vivo
28. The Role of Jun, Fos and the AP-1 Complex in Cell Proliferation and Transformation
29. Control of Transcription Factor Activity by Phosphorylation: the Beginning of the End
30. Activation of Protein Kinase C Decreases Phosphorylation of c-Jun at Sites that Negatively Regulate its DNA-Binding Activity
31. Casein Kinase II Is a Negative Regulator of cJun DNA Binding and AP-1 Activity
32. Inhibition of c-Jun DNA Binding by Mitogen-Activated Protein Kinase
33. Pro-Leu-Ser/Thr-Pro Is a Consensus Primary Sequence for Substrate Protein Phosphorylation
34. Phosphorylation of cJun on Serines 63 and 73 Is Required for Oncogenic and Transcriptional Cooperation with Ha-Ras
35. Oncoprotein-Mediated Signalling Cascade Stimulates cJun Activity by Phosphorylation of Serines 63 and 73
36. Phosphorylation of c-jun Mediated by MAP Kinases
37. Co-Purification of Mitogen Activated Protein Kinases with Phorbol Ester Induced cJun Kinase Activity in U937 Leukaemic Cells
38. The Mammalian UV-Response Is Triggered by the Activation of Protein Tyrosine Kinases
39. Ras Is Essential for Nerve Growth Factor and Phorbol Ester Induced Tyrosine Phosphorylation of MAP Kinases
40. Identification of an Oncoprotein- and UV-Responsive Protein Kinase that Binds and Potentiates the c-Jun Activation Domain
41. JNK1: A Protein Kinase Stimulated by UV Light and Ha-Ras that Binds and Phosphorylates the c-Jun Activation Domain
42. The Jun Protooncogene Is Positively Autoregulated by its Product, Jun.AP-1
43. Interferon-Induced Nuclear Factors that Bind a Shared Promoter Element Correlate with Positive and Negative Transcriptional Control
44. Cytoplasmic Activation of ISGF3, the Positive Regulator of Interferon-α-Stimulated Transcription, Reconstituted in Vitro
45. ISGF3, the Transcriptional Activator Induced by Interferon α, Consists of Multiple Interacting Polypeptide Chains
46. Subunit of an α-Interferon-Responsive Transcription Factor Is Related to Interferon Regulatory Factor and Myb Families of DNA-Binding Proteins
47. Proteins of Transcription Factor ISGF-3: One Gene Encodes the 91- and 84-kDa ISGF-3 Proteins that Are Activated by Interferon α
48. The Proteins of ISGF-3, the Interferon α-Induced Transcriptional Activator, Define a Gene Family Involved in Signal Transduction
49. A Transcription Factor with SH2 and SH3 Domains Is Directly Activated by an Interferon α-Induced Cytoplasmic Protein Tyrosine Kinase(s)
50. SH2 and SH3 Domains: From Structure to Function
51. Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor
52. A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-Gamma
53. Two Domains of ISGF3 γ that Mediate Protein DNA and Protein-Protein Interactions during Transcription Factor Assembly Contribute to DNA-Binding Specificity
54. Interferon-α Regulates Nuclear Translocation and DNA-Binding Affinity of ISGF3, a Multimeric Transcriptional Activator
55. Overlapping Elements in the Guanylate Binding Protein Gene Promoter Mediate Transcriptional Induction by α and γ Interferons
56. Characterization of the Promoter of the Human Gene Encoding the High Affinity IgG Receptor: Transcriptional Induction by γ-Interferon Is Mediated through Common DNA Response Elements
57. Cytoplasmic Activation of GAF, an Interferon-Regulated DNA Binding Factor
58. Activation of Transcription by IFN-γ. Tyrosine Phosphorylation of a 91-kD DNA Binding Protein
59. A Novel cis Element Mediating Ligand-Independent Activation by c-ErbA: Implications for Hormonal Regulation
60. Use of a Selectable Marker Regulated by alpha Interferon to Obtain Mutations in the Signalling Pathway
61. A Protein Tyrosine Kinase in the Interferon α/β Signalling Pathway
62. Complementation by the Protein Tyrosine Kinase YAK2 of a Mutant Cell Line Defective in the Interferon-γ Signal Transduction Pathway
63. The Protein Kinase JAK1 Complements Defects in Interferon-α/β and -γ Signal Transduction
64. Cytokine Connections
65. Inducible Binding of a Factor to the c-fos Regulatory Region
66. Cell-Free Activation of a DNA-Binding Protein by Epidermal Growth Factor
67. Induction of EGF and Interferon-γ of Tyrosine Phosphorylated DNA Binding Proteins in Mouse Liver Nuclei
68. Ras-Independent Growth Factor Signalling by Transcription Factor Tyrosine Phosphorylation
69. Transcription Factor p91 Interacts with the Epidermal Growth Factor Receptor and Mediates Activation of the c-fos Gene Promoter
70. Polypeptide Signalling to the Nucleus through Tyrosine Phosphorylation of Jak and Stat Proteins
71. JAK2 associates with the erythro-poietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
72. Identification of JAK2 as a Growth Hormone Receptor-Associated Tyrosine Kinase
73. Tyrosine Phosphorylation of DNA Binding Proteins by Multiple Cytokines
74. Protein kinase recognition sequence motifs
75. Pheromone Response in Yeast
76. FUS3 Phosphorylates Multiple Components of the Mating Signal Transduction Cascade: Evidence for STE12 and FAR1