Identification and purification of an agrin receptor from torpedo postsynaptic membranes: A heteromeric complex related to the dystroglycans

Neuron

Volumn 12, Issue 5, 1994, Pages 1173-1180

  Bowe, Mark A ^a   Deyst, Katherine A ^a   Leszyk, John D ^a   Fallon, Justin R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; AGRIN; CHOLINERGIC RECEPTOR; DYSTROPHIN; GLYCOPROTEIN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; NEUROTRANSMITTER; RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ELECTRIC ORGAN; EXTRACELLULAR MATRIX; IMMUNOAFFINITY CHROMATOGRAPHY; IMMUNOASSAY; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; TORPEDO CALIFORNICA;

AGRIN; AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, MONOCLONAL; CELL MEMBRANE; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, GEL; COMPARATIVE STUDY; CYTOSKELETAL PROTEINS; DYSTROPHIN; ELECTRIC ORGAN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMAN; IMMUNOBLOTTING; MEMBRANE GLYCOPROTEINS; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NEURONS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; RECEPTORS, GROWTH FACTOR; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SYNAPSES; TORPEDO;

EID: 0028321841     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(94)90324-7     Document Type: Article

References (50)

1. Basic local alignment search tool
2. NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampu
3. Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans
4. The role of agrin in synapse formation.
5. Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites
6. The distribution of glutamate receptors in cultured rat hippocampal neurons: postsynaptic clustering of AMPA-selective subunits
7. Conversion of acetylcholine receptor dimers to monomers upon depletion of nonreceptor peripheral proteins
8. Membrane organization of the dystrophin-glycoprotein complex
9. A role for the dystrophinglycoprotein complex as a transmembrane linker between laminin and actin
10. Agrin-related molecules are concentrated at acetylcholine receptor clusters in normal and aneural developing muscle
11. Acetylcholine receptor-aggregating factor is si milar to molecules concentrated at neuromuscular junctions
12. ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the Neu ligand family
13. An improved procedure for enzymatic digestion of polyvinylidene difluoride bound proteins for internal sequence analysis
14. RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity in cultured myotubes
15. Quantitation of functional and extrajunctional acetylcholine receptors by electron microscope autoradiography after 1251-a bungarotoxin binding at mouse neuromuscular junctions
16. The submembrane machinery for nicotinic acetylcholine receptor clustering
17. Laminin-binding protein 120 from brain is closely related to the dystrophin-associated glycoprotein, dystroglycan, and binds with high affinity to the major heparin binding domain of laminin
18. Components of Torpedo electric organ and muscle that cause aggregation of acetylcholine receptors on cultured muscle cells
19. Basal lamina components are concentrated in premuscle masses and at early acetylcholine receptor clusters in chick embryo hindlimb muscles
20. Synaptic structure and development: the neuromuscular junction
21. Synaptic structure and development: the neuromuscular junction
22. The absence of calcium blocks impulse-evoked release of acetylcholine but not de novo formation of functional neuromuscular synaptic contacts in culture
23. Integrins: versatility, modulation, and signaling in cell adhesion
24. Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix
25. Human dystroglycan: skeletal muscle cDNA, genomic structure, origin of tissue specific isoforms and chromosomal localization
26. Surface and intracellular distribution of a putative neuronal nicotinic acetylcholine receptor
27. Synaptic transmission: a bidirectional and self-modifiable form of cell-cell communication
28. Synaptic transmission: a bidirectional and self-modifiable form of cell-cell communication
29. The agrin receptor: localization in the postsynaptic membrane, interaction with agrin, and relationship to the acetylcholine receptor
30. Interaction of the 43 kd postsynaptic protein with all subunits of the muscle nicotinic acetylcholine receptor
31. Association of dystrophin-related protein with dystropin-associated proteins in mdx mouse muscle
32. Visual identification of synaptic boutons on living ganglion cells and of varicosities in postganglionic axons in the heart of the frog
33. Molecules in basal lamina that direct the formation of synaptic specializations at neuromuscular junctions
34. Agrin and the molecular choreography of synapse formation
35. The putative agrin receptor binds ligand in a calcium-dependent manner and aggregates during agrin-induced acetylcholine receptor clustering
36. Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides
37. Identification of agrin, a synaptic organizing protein from Torpedo electric organ
38. Localization and alternative splicing of agrin mRNA in adult rat brain: transcripts encoding active isoforms are not restricted to cholinergic regions
39. Agrin-like molecules at synaptic sites in normal, denervated, and damaged skeletal muscles
40. Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions
41. Structure and expression of a rat agrin
42. A one-step purification of membrane proteins using a high efficiency immunomatrix
43. Clustering of the acetylcholine receptor by the 43-kd protein: involvement of the zinc finger domain
44. Isolation and characterization of a cDNA that encodes an agrin homolog in the marine ray
45. Nicotinic postsynaptic membranes from Torpedo: sidedness, permeability to macromolecules, and topography of major polypeptides
46. Distribution of glycine receptors at central synapses: an immunoelectron microscopy study
47. cDNA that encodes active agrin
48. ++ and phorbol ester
49. Agrin induces phosphorylation of the nicotinic acetylcholine receptor