Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences

Nucleic Acids Research

Volumn 22, Issue 3, 1994, Pages 301-307

  Pachuk, Catherine ^a   Yoon, Kyonggeun ^a   Moelling, Karin ^a,b,c   Coney, Leslie R ^a  

^a Apollon ^*  (United States)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; RIBOZYME; RNA;

ARTICLE; BINDING KINETICS; BINDING SITE; CATALYSIS; CONTROLLED STUDY; GEL ELECTROPHORESIS; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; RNA SEQUENCE;

BASE SEQUENCE; DNA PRIMERS; FUSION PROTEINS, BCR-ABL; HUMANS; HYDROGEN BONDING; KINETICS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RNA, CATALYTIC; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0028318142     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/22.3.301     Document Type: Article

References (15)

1. Nowell, P.C., and Hungerford, D.A., (1960) Science, 132, 1497-1499.
2. Rowley, J.D., (1973) Nature, 243, 290 -293
3. Grofen, J., Stephenson, J.R., Heisterkamp, N., de Klein, A., Baitram, C.R., and Growveld, G., (1984) Cell, 36, 9 -93.
4. Heisterkamp, N., Stephenson, J.R., Groffen, J., Hansen, P.F., de Klein, A., Bartram, C.R., and Grosveld, G., (1983) Nature, 306, 239—242.
5. Shtivelman, E., Ufshitz, B., Gale, R.P., Roe, B.A., and Canaani, J., (1986) Cell, 47, 277 -284.
6. Beaucage, S., and Carutbers, M., (1981) Tetrahedron Lett., 22, 1859-1862.
7. Heisterkamp, N., Stara, K., and GrofTen, J., (1985) Nature, 315, 758-761.
8. Lozzio, C.B., and Lozzio, B.B., (1975) Blood, 45, 321-334.
9. Innis, M.A., Gelfond, D.H., Sninsky, J.J., and White, TJ., (1990) PCR Protocols, A Guide to Methods and Applications, Academic Press, Inc., San Diego, CA.
10. Sambrook, S., Fritsch, E.F., and Maniaiis, T., (1989) Molecular Cloning, A Laboratory Manual, 2nd Ed., Cok) Spring Harbor Press, Cold Spring Harbor, NY.
11. Boyer, P.D., (1970) The Enzymes, Student Ed., Academic Press, Inc., New York, NY.
12. Haselof, TJ., and Geiiach, W.L., (1988) Nature, 334, 585 - 591.
13. Taylor, N.R., and Rossi, J.J., (1991) Antisense Res. Dev., 1, 173 — 186.
14. Fedor, M.J., and Uhlenbeck, O.C., (1990) Proc. Natl. Acad. Sci. USA, 87, 1668-1671.
15. Fedor, M.J., and Uhlenbeck, O.C., (1992) Biochemistry, 31, 12042-12054.