Towards understanding the three-dimensional structure of the nuclear pore complex at the molecular level

Current Opinion in Structural Biology

Volumn 4, Issue 2, 1994, Pages 187-196

  Panté, Nelly ^a,b   Aebi, Ueli ^a,b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPORIN;

CYTOPLASM; MEMBRANE TRANSPORT; MOLECULAR GENETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; REVIEW; STRUCTURE ACTIVITY RELATION; YEAST;

EID: 0028316365     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(94)90307-7     Document Type: Article

References (62)

1. Correlation Between Structure and Mass Distribution of the Nuclear Pore Complex, and of Distinct Pore Complex Components
2. A Large Particle Associated with the Perimeter of the Nuclear Pore Complex
3. Interactions and Structure of the Nuclear Pore Complex Revealed by Cryo-Electron Microscopy
4. Towards a More Complete 3-D Structure of the Nuclear Pore Complex
5. Architecture and Design of the Nuclear Pore Complex
6. Architecture of the Xenopusnuclear Pore Complex Revealed by Three-Dimensional Cryo-Electron Microscopy
7. Cytosolic Proteins that Specifically Bind Nuclear Localization Signals are Receptors for Nuclear Innport
8. The Two Steps of Nuclear Import, Targeting to the Nuclear Envelope and Translocadon Through the Nuclear Pore, Require Different Cytosolic Factors
9. The GTP Binding Protein Ran/TC4 is Required for Protein Import into the Nucleus
10. Inhibition of Nuclear Protein Import by Nonhydrolyrlple Analogues of GTP and Identification of the Small GTPase Ran/rC4 as an Essential Transport Factor
11. Monomethylated Cap Structures Facilitate RNA Export from the Nucleus
12. Nuclear Export of Different Classes of RNA is Mediated by Specific Factors
13. The Nuclear Pore Complex
14. Structure and Function of the Nuclear Pore Complex
15. Molecular Trafficking Across the Nuclear Pore Complex
16. Nuclear Pore Structure and Function
17. The Nuclear Pore Complex and Nucleocy toplasmic Transport
18. The Nuclear Pore Complex
19. Visualization of Transport-Related Configurations of the Nuclear Pore Transporter
20. The Amino-Terminal Domain of the Lamin B Receptor is a Nuclear Envelope Targeting Signal
21. Nuclear Membrane Dynamics
22. The 3-D Structure of the Nuclear Pore Complex as Seen by High Voltage Electron Microscopy and High Resolution Low Voltage Scanning Electron Microscopy
23. High Resolution Scanning Electron Microscopy of the Nuclear Envelope: Demonstration of a new, Regular, Fibrous Lattice Attached to the Baskets of the Nucleoplasmic Face of the Nuclear Pores
24. Isolation of the Yeast Nuclear Pore Complex
25. The Nuclear Pore Complex: Three-Dimensional Surface Structure Revealed by Field Emission, In-Lens Scanning Electron Microscopy, with Underlaying Structure Uncovered by Proteolysis
26. Selective Digestion of Nuclear Envelopes from Xenopus Oocyte Germinal Vesicles: Possible Structural Role for the Nuclear Lamine
27. Exploring Native Nuclear Pore Complex Structure and Conformation by Scanning Force Microscopy in Physiological Buffers
28. The Structure and Interactions of Components of Nuclear Envelopes from Xenopus Oocyte Germinal Vesicles Observed by Heavy Metal Shadowing
29. Vaults. III. Vault Ribonucleoprotein Particles Open into Flower-Like Structures with Octagonal Symmetry
30. Localization of Vault Particles to the Nuclear Pore Complex
31. Monoclonal Antibodies Identify a Group of Nuclear Pore Complex Glycoproteins
32. Nuclear Pore Complex Glycoproteins Contain Cytoplasmically Disposed O-Linked N-Acetylglucosamine
33. The Nuclear Pore Complex Contains a Family of Glycoproteins that Includes p62: Glycosylation Through a Previously Unidentified Cellular Pathway
34. Nup155 is a Novel Nuclear Pore Complex Protein that Contains Neither Repetitive Sequence Motifs nor Reacts with WGA
35. A Nuclear Pore Complex Protein that Contains Zinc Finger Motifs, Binds DNA, and Faces the Nucleopiasm
36. Sequence Analysis of a cDNA Encoding a Human Nuclear Pore Complex Protein hnup53
37. Nup180, a Novel Nuclear Pore Complex Protein Localizing to the Cytoplasmic Ring and Associated Fibrils
38. Nucleotidc Sequence Analysis of Human tpr cDNA clones
39. Role of Different Domains in the Self-Association of Rat Nucleoporin p62
40. Primary Sequence and Heterologous Expression of Nuclear Pore Glycoprotein p62
41. Human Nuclcoporin p62 and the Essential Yeast Nuclear Pore Protein NSP1 Show Sequence Homology and a Similar Domain Organization
42. Nuclear Pore Complex Glycoprotein p62 of Xenopus laevis and Mouse: cDNA Cloning and Identification of its Glycosylation Region
43. An Integral Membrane Protein of the Pore Membrane Domain of the Nuclear Envelope Contains a Nucleoporin-Like Region
44. Nuclear Protein Localization
45. O-Linked Glycoproteins of the Nuclear Pore Complex Interact with a Cytosolic Factor Required for Nuclear Protein Import
46. An N-Ethylmaleimide-Sensitive Cytosolic Factor Necessary for Nuclear Protein Import: Requirement in Signal-Mediated Binding to the Nuclear Pore
47. Molecular Genetic Tools for Study of the Cytoskeleton in Dictyostelium
48. Intranuclear Filaments Containing a Nuclear Pore Complex Protein
49. High-Resolution Field Emission Scanning Electron Microscope Imaging of Internal Cell Structures after Epon Extraction from Sections: A New Approach to Coorelative Ultrastructural and Immunocytochemical Studies
50. The Human CAN Protein, a Putative Oncogenc Product Associated with Myeloid Leukemogenesis, is a Nuclear Pore Complex Protein that Faces the Cytoplasm
51. The Transiocation (6;9), Associated with a Specific Subtype of Acute Myeloid Leukemia, Results in the Fusion of Two Genes, dek and can, and the Expression of a Chimeric, Leukemia-Specific dek-can mRNA
52. Identification of a Major Polypeptide of the Nuclear Pore Complex
53. Primary Structure Analysis of an Integral Membrane Glycoprotein of the Nuclear Pore
54. A Major Glycoprotein of the Nuclear Pore Complex is a Membrane-Spanning Polypeptide with a Large Lumenal Domain and a Small Cytoplasmic Tail
55. The Single Tmnsmembrane Seg- ment of gp210 is Sufficient for Sorting to the Pore Membrane Domain of the Nuclear Envelope
56. A Complex of Nuclear Pore Proteins Required for Pore Function
57. A Novel Nucleoskeletal-Like Protein Located at the Nuclear Periphery is Required for jhe Life Cycle of Saccbaromyces cerevisiae
58. The NUP1 Gene Encodes an Essential Component of the Yeast Nuclear Pore Complex
59. NUP2, a Novel Yeast Nucleoporin, has Functional Overlap with Other Proteins of the Nuclear Pore Complex
60. A New Family of Yeast Nuclear Pore Complex Proteins
61. A New Subclass of Nucleoporins that Functionally Interact with Nuclear Pore Protein NSPI
62. A Temperature-Sensitive NUP116 Null Mutant Forms a Nuclear Envelope Seal Over the Yeast Nuclear Pore Complex Thereby Blocking Nucleocytoplasmic Traffic