6-(1H-Imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione Hydrochloride (YM90K) and Related Compounds: Structure-Activity Relationships for the AMPA-Type Non-NMDA Receptor

Journal of Medicinal Chemistry

Volumn 37, Issue 4, 1994, Pages 467-475

  Ohmori, Junya ^a   Sakamoto, Shuichi ^a   Kubota, Hirokazu ^a   Shimizu Sasamata, Masao ^a   Okada, Masamichi ^a   Kawasaki, Sachiko ^a   Hidaka, Kazuyuki ^a   Togami, Junzi ^a   Furuya, Toshio ^a   Murase, Kiyoshi ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 QUINOXALINEDIONE DERIVATIVE; 6 (1 IMIDAZOLYL) 7 NITRO 2,3 QUINOXALINEDIONE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; ANTICONVULSIVE AGENT; EXCITATORY AMINO ACID RECEPTOR; KAINIC ACID; KAINIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CORPUS STRIATUM; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; RAT; RECEPTOR AFFINITY; SEIZURE; STRUCTURE ACTIVITY RELATION;

ACOUSTIC STIMULATION; ANIMAL; ANTICONVULSANTS; BINDING SITES; BRAIN; COMPARATIVE STUDY; IMIDAZOLES; MALE; MICE; MICE, INBRED DBA; QUINOXALINES; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0028314957     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00030a006     Document Type: Article

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