Application of hydroxyapatite-sol as drug carrier

Bio-Medical Materials and Engineering

Volumn 4, Issue 4, 1994, Pages 283-290

  Kano, Seisuke ^a   Yamazaki, Atsushi ^b   Otsuka, Ryohei ^b   Ohgaki, Masataka ^c   Akao, Masaru ^c   Aoki, Hideki ^c  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Drug carrier; Hydroxyapatite sol; Nano crystals

Indexed keywords

CALCIUM HYDROXIDE; DOXORUBICIN; DRUG CARRIER; HYDROXYAPATITE; METHACRYLIC ACID METHYL ESTER; PHOSPHORIC ACID;

ADSORPTION; ARTICLE; CELL CULTURE; CHEMISTRY; COLLOID; CRYSTALLOGRAPHY; HUMAN; MOUTH TUMOR; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SYNTHESIS; ULTRASOUND; X RAY DIFFRACTION;

ADSORPTION; CALCIUM HYDROXIDE; COLLOIDS; CRYSTALLOGRAPHY; DOXORUBICIN; DRUG CARRIERS; DURAPATITE; HUMAN; METHYLMETHACRYLATE; METHYLMETHACRYLATES; MICROSCOPY, ELECTRON, SCANNING; MOUTH NEOPLASMS; PARTICLE SIZE; PHOSPHORIC ACIDS; TUMOR CELLS, CULTURED; ULTRASONICS; X-RAY DIFFRACTION;

EID: 0028310514     PISSN: 09592989     EISSN: 18783619     Source Type: Journal    
DOI: 10.3233/BME-1994-4404     Document Type: Article

References (20)

1. Ohnishi, M. the clinical applications of hydroxyapatite porous blocks in oral and maxillofacial surgery. Bioceramics 1:108-117; 1989.
2. Hasegawa, S., Furuya, K., Okumura, S., Fushimi, M., Aoki, H., Akao, M., Higashikata, M., Ukegawa, Y. Interface between the hydroxyapatite coated SUS316 stainless steel and bone under load-bearing conditions. Bioceramics 1:382-387; 1989.
3. Shinto, Y., Uchida, A., Korkusuz, F., Araki, N., Ono, K. Calcium hydroxyapatite ceramic used as a delivery system for antibiotics. J. Bone Joint Surg. 746:600-604; 1992.
4. Nihon-Kagakukai. Bunseki-Kagakubinran, 3rd. ed. Japan: Maruzen; 1958:56.
5. Murphy, J., Riley, J. P. A modified single solution method for the determination of phosphate in natural waters. Anal. Chem. Acta 27:31-36; 1962.
6. Conway, E. J. Micro diffusion analysis and volumetric error. London; 1955.
7. Somasundaran, P. Zeta potential of apatite in aqueous solutions and its change during equilibrium. J. Coll. Int. Sci. 27:659-666; 1968.
8. Arcamone, F., Cassinelli, G., Franceschi, G., Penco, S.; Pol, C., Redaelli, S., Sevla, A. Structure and physicochemical properties of adriamycin. International Symposium on Adriamycin; 1972.
9. Horikoshi, M., Kimura, Y., Nagura, H., Ono, T.; Ito, H. A new human cell line derived from human carcinoma of the gingiva I. Its establishment and morphological studies. Int. J. Oral Maxillofac. Surg. 20:100-1-6; 1974.
10. Elliott, J. C., Holcomb, D. W., Young, R. D. Infrared determination of the degree of substitution of hydroxyl and carbonate ions in human dental enamel. Calcif. Tissue Int. 37:372-375; 1975.
11. Greenfield, D. J., Termine, J. D., Eance, E. D. A chemical study of apatites prepared by hydrolysis of amorphous calcium phosphates in carbonate-containing aqueous solutions. Calcif. Tissue Res. 14:131-138; 1974.
12. Fowler, B. O., Moreno, E. C., Brown, W. E. Infra-red spectra of hydroxyapatite, octacalcium phosphate and pyrolysed octacalcium phosphate. Arch. Oral Biol. 11:477-492; 1966.
13. Kanazawa, T., Umegaki, T., Uchiyama, N. Thermal crystallisation of amorphous calcium phosphate to a-tricalcium phosphate. J. Chem. Tech. Biotech. 32:399-106; 1982.
14. 2O in human enamel and precipitated apatites. Calcif. Tissue Res. 26:111-118; 1978.
15. Harper, R. A., Posner, A. S. Radial distribution study of noncrystalline tricalcium phosphate. Mat. Res. Bull. 5:129-136; 1970.
16. Posner, A. S. Calculation of X-ray intensities from arrays of small crystallites of hydroxyapatite. Arch. Biochem. Biophys. 124:604-615, 1968.
17. Hall, W. H. Crystallite theory of strength of materials. J. Inst. Met. 75:1127-1129; 1950.
18. Misra, D. N. Adsorption and orientation of tetracycline on hydroxyapatite. Calcif. Tissue Int. 48:362-367, 1991.
19. Kawasaki, T. Hydroxyapatite as a liquid chromatographic packing. J. Chromatography 544:47-184, 1991.
20. Aoki, H., Akao, M., Kano, S., Matsumoto, K., Ogawa, Y., Sakatsume, M., Effect of hydroxyapatite-sol on cell growth. Rep. Int. Med. Dent. Eng., Tokyo Med. Dent. Univ. 26:15-21; 1992.