Measurement of liver microsomal cytochrome P450 (CYP2D6) activity using [O-methyl-14C] dextromethorphan

Analytical Biochemistry

Volumn 219, Issue 2, 1994, Pages 309-320

  Rodrigues, A D ^a   Kukulka, M J ^a   Surber, B W ^a   Thomas, S B ^a   Uchic, J T ^a   Rotert, G A ^a   Michel, G ^b   Thome Kromer, B ^b   Machinist, J M ^a  

^a ABBOTT LABORATORIES   (United States)

^b ABBOTT GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL REACTIONS; DICHLOROMETHANE; FORMALDEHYDE; SODIUM HYDROXIDE;

DEMETHYLASE ACTIVITY; DEXTROMETHORPHAN; HUMAN LIVER MICROSOMES; INTERNAL STANDARDS; LIMIT OF DETECTION; MICROSOMAL PROTEINS; PROTEIN CONCENTRATIONS; QUANTITATIVE MEASUREMENT;

PROTEINS;

CYTOCHROME P450; DEXTROMETHORPHAN;

ARTICLE; DEMETHYLATION; ENZYME ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; PRIORITY JOURNAL;

EID: 0028305918     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1006/abio.1994.1271     Document Type: Article

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