Biodegradable microspheres as depot system for patenteral delivery of peptide drugs

Journal of Controlled Release

Volumn 29, Issue 3, 1994, Pages 375-384

  Mehta, Rahul C ^a   Jeyanthi, Ramasubbu ^a   Calls, Sema ^a   Thanoo, B C ^a   Burton, Kevin W ^a   DeLuca, Patrick P ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Biodegradable microsphere; Drug delivery; Lactide glycolide polymer; Peptide; Salmom calcitonin

Indexed keywords

COPOLYMER; MICROSPHERE; PEPTIDE; POLYGLACTIN; SALCATONIN;

ANIMAL EXPERIMENT; BIODEGRADATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ADMINISTRATION; DRUG ADSORPTION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG RELEASE; FEMALE; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; PHARMACEUTICS; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SUBCUTANEOUS DRUG ADMINISTRATION; TEMPERATURE;

EID: 0028305884     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(94)90082-5     Document Type: Article

References (20)

1. Release of norethindrone from poly(ortho esters)
2. Controlled Release of Biologically Active Agents
3. Biological substrates and cure rates of cyanoacrylate tissue adhesives
4. Long-acting delivery systems for narcotic antagonists
5. New absorbable suture
6. Degradable polymers for sustained drug release
7. Sustained drug delivery systems II. Factors affecting release rates from poly (-caprolactone) and related biodegradable polyesters
8. Glycolide and lactide copolymers for slow release of chemotherapeutic agents
9. Biodegradable cisplatin microspheres prepared by the solvent evaporation method: morphology and release characteristics
10. The acceleration of degradation controlled drug delivery from polyester microspheres
11. The effect of the addition of low molecular weight poly (dl-lactide) on drug release from biodegradable poly (dl-lactide) drug delivery systems
12. Magnetic microspheres: synthesis of novel parenteral drug carrier
13. Development of a biodegradable microsphere formulation for the sustained release of a bioactive peptide
14. Biodegradable polymers for use in surgery
15. Biodegradable poly(lactic acid) polymers
16. In vivo characteristics of high molecular weight co poly (l-lactide/glycolide) with S-type degradation pattern for application in drug delivery systems
17. Poly (lactide/glycolide) biodegradable drug polymer matrix system
18. Influence of processing parameters on the porosity of poly(glycolide-co-lactide) microspheres