메뉴 건너뛰기




Volumn 54, Issue 8, 1994, Pages 2064-2068

Hepatocarcinoma-specific Mutant p53-249ser Induces Mitotic Activity but Has No Effect on Transforming Growth Factor /β1-mediated Apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0028300183     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (86)

References (24)
  • 1
    • 0026579237 scopus 로고
    • TP53 tumor suppressor gene: a model for investigating human mutagenesis
    • Caron de Fromentel, C. and Soussi, T. TP53 tumor suppressor gene: a model for investigating human mutagenesis. Genes Chromosomes Cancer, 4: 1-15, 1992.
    • (1992) Genes Chromosomes Cancer , vol.4 , pp. 1-15
    • Caron de Fromentel, C.1    Soussi, T.2
  • 3
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p. 3
    • Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J. and Howley, P. M. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p. 3. Cell, 63: 1129-1136, 1990.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 4
    • 0025748539 scopus 로고
    • p. 3 mutation in hepatocellular carcinoma after aflatoxin exposure
    • Ozturk, M., et al. p. 3 mutation in hepatocellular carcinoma after aflatoxin exposure. Lancet, 338: 1356-1359, 1991.
    • (1991) Lancet , vol.338 , pp. 1356-1359
    • Ozturk, M.1
  • 5
    • 0026356298 scopus 로고
    • Selective targeting of p. 3 gene mutational hotspots in human cancers by etiologically defined carcinogens
    • Puisieux, A., Lim, S. Groopman, J. and Ozturk, M. Selective targeting of p. 3 gene mutational hotspots in human cancers by etiologically defined carcinogens. Cancer Res. 57: 6185-6189, 1991.
    • (1991) Cancer Res. , vol.57 , pp. 6185-6189
    • Puisieux, A.1    Lim, S.2    Groopman, J.3    Ozturk, M.4
  • 6
    • 0025085667 scopus 로고
    • Different tumor-derived p. 3 mutants exhibit distinct biological activities
    • Halevy, O., Michalovitz, D. and Oren, M. Different tumor-derived p. 3 mutants exhibit distinct biological activities. Science (Washington DC), 250: 113-116, 1990.
    • (1990) Science (Washington DC) , vol.250 , pp. 113-116
    • Halevy, O.1    Michalovitz, D.2    Oren, M.3
  • 7
    • 0027210981 scopus 로고
    • Gain of function mutations in p. 3
    • Dittmer, D., et al. Gain of function mutations in p. 3. Nat. Genet. 4: 42-45, 1993.
    • (1993) Nat. Genet. , vol.4 , pp. 42-45
    • Dittmer, D.1
  • 8
    • 0025611503 scopus 로고
    • Genetic mechanisms of tumor suppression by the human p. 3 gene
    • Chen, P. L., Chen, Y. M., Bookstein, R. and Lee, W. H. Genetic mechanisms of tumor suppression by the human p. 3 gene. Science (Washington DC), 250: 1576-1580, 1990.
    • (1990) Science (Washington DC) , vol.250 , pp. 1576-1580
    • Chen, P.L.1    Chen, Y.M.2    Bookstein, R.3    Lee, W.H.4
  • 9
    • 0027500250 scopus 로고
    • p. 3 as a growth suppressor gene in HBV-related hepatocellular carcinoma cells
    • Puisieux, A., Ponchel, F. and Ozturk, M. p. 3 as a growth suppressor gene in HBV-related hepatocellular carcinoma cells. Oncogene, 8: 487-490, 1993.
    • (1993) Oncogene , vol.8 , pp. 487-490
    • Puisieux, A.1    Ponchel, F.2    Ozturk, M.3
  • 10
    • 0027078647 scopus 로고
    • A functional screen for germ line p. 3 mutations based on transcriptional activation
    • Frebourg, T., et al. A functional screen for germ line p. 3 mutations based on transcriptional activation. Cancer Res. 52: 6976-6978, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 6976-6978
    • Frebourg, T.1
  • 11
    • 0025262417 scopus 로고
    • Abnormal structure and expression of p. 3 gene in human hepatocellular carcinoma
    • Bressac, B., et al. Abnormal structure and expression of p. 3 gene in human hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA, 87: 1973-1977, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1973-1977
    • Bressac, B.1
  • 12
    • 0027411355 scopus 로고
    • Production of human p. 3 specific monoclonal antibodies and their use in immunohistochemical studies of tumor cells
    • Legros, Y., et al. Production of human p. 3 specific monoclonal antibodies and their use in immunohistochemical studies of tumor cells. Bull. Cancer (Paris), 80: 102-110, 1993.
    • (1993) Bull. Cancer (Paris) , vol.80 , pp. 102-110
    • Legros, Y.1
  • 13
    • 0026785357 scopus 로고
    • An image cytometric DNA-analysis in breast neoplasms
    • Longin, A. An image cytometric DNA-analysis in breast neoplasms. Pathol. Res. Pract. 188: 466-472, 1992.
    • (1992) Pathol. Res. Pract. , vol.188 , pp. 466-472
    • Longin, A.1
  • 14
    • 0025830047 scopus 로고
    • Effect of transforming growth factor 0 on cell death of cultured rat hepatocytes
    • Oberhammer, F., et al. Effect of transforming growth factor 0 on cell death of cultured rat hepatocytes. Cancer Res. 51: 2478-2485, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 2478-2485
    • Oberhammer, F.1
  • 15
    • 0027517726 scopus 로고
    • Retinoblastoma and p. 3 tumor suppressor genes in human hepatoma cell lines
    • Puisieux, A., et al. Retinoblastoma and p. 3 tumor suppressor genes in human hepatoma cell lines. FASEB J. 7: 1407-1413, 1993.
    • (1993) FASEB J. , vol.7 , pp. 1407-1413
    • Puisieux, A.1
  • 16
    • 0028029126 scopus 로고
    • p. 3 overexpression is frequent in European hepatocellular carcinoma and largely independent of the codon 249 hot spot mutation
    • Volkmann, M., et al. p. 3 overexpression is frequent in European hepatocellular carcinoma and largely independent of the codon 249 hot spot mutation. Oncogene, 9: 195-204, 1994.
    • (1994) Oncogene , vol.9 , pp. 195-204
    • Volkmann, M.1
  • 17
    • 0026769457 scopus 로고
    • Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor-01
    • F. Oberhammer, et al. Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor-01. Proc. Natl. Acad. Sci. USA, 89: 5408-5412, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5408-5412
    • Oberhammer, F.1
  • 19
    • 0026584374 scopus 로고
    • In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor-01
    • Lin, J. K. and Chou, C. K. In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor-01. Cancer Res. 52: 385-388, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 385-388
    • Lin, J.K.1    Chou, C.K.2
  • 20
    • 0026642195 scopus 로고
    • Induction of apoptosis in fibroblasts by c-myc protein
    • Evan, G. I., et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell, 69: 119-128, 1992.
    • (1992) Cell , vol.69 , pp. 119-128
    • Evan, G.I.1
  • 21
    • 0025221676 scopus 로고
    • Addition of fresh medium induces cell cycle and conformation changes in p. 3 a tumor suppressor protein
    • Milner J. and Watson, J. V. Addition of fresh medium induces cell cycle and conformation changes in p. 3, a tumor suppressor protein. Oncogene, 5: 1683-1690, 1990.
    • (1990) Oncogene , vol.5 , pp. 1683-1690
    • Milner, J.1    Watson, J.V.2
  • 22
    • 0021379737 scopus 로고
    • Role of p. 3 protein in cell proliferation as studied by microinjection of monoclonal antibodies
    • Mercer, W. E., Avignolo, C. and Baserga, R. Role of p. 3 protein in cell proliferation as studied by microinjection of monoclonal antibodies. Mol. Cell. Biol. 4: 276-281, 1984.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 276-281
    • Mercer, W.E.1    Avignolo, C.2    Baserga, R.3
  • 23
    • 0027465080 scopus 로고
    • Mutant p. 3 tumor suppressor gene causes resistance to transforming growth factor 0-1 in murine keratinocytes
    • Reiss, M., Velluchi, V. F. and Zhou, Z. Mutant p. 3 tumor suppressor gene causes resistance to transforming growth factor 0-1 in murine keratinocytes. Cancer Res. 53: 899-904, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 899-904
    • Reiss, M.1    Velluchi, V.F.2    Zhou, Z.3
  • 24
    • 0026572475 scopus 로고
    • Mutant p. 3 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor 0-1
    • Gerwin, B. I., et al. Mutant p. 3 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor 0-1. Proc. Natl. Acad. Sci. USA, 89: 2759-2763, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2759-2763
    • Gerwin, B.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.