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Volumn 50, Issue 20, 1994, Pages 6117-6128

Highly enantioselective addition of primary alkyl Grignard reagents to carbocyclic and heterocyclic arylketones in the presence of magnesium TADDOLate preparative and mechanistic aspects

Author keywords

[No Author keywords available]

Indexed keywords

ALKANOL; MAGNESIUM DERIVATIVE; METAL COMPLEX;

EID: 0028298616     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)90463-6     Document Type: Article
Times cited : (121)

References (66)
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    • The following papers describe the, so far, most general method for the addition of primary alkyl Zn reagents to non-functionalized aliphatic, α,β-unsaturated (CC and CC), aromatic and heteroaromatic aldehydes with formation of secondary alcohols of ≥97% ee, using the Ti-TADDOLate from 1b:
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    • The α-heteroatom in 2-furyl- and 2-pyridyl methyl ketone seems to interfere with the reaction as well, see 15 and 20, but also 13!
  • 47
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.