Large-scale insect and plant cell culture

Current Opinion in Biotechnology

Volumn 5, Issue 2, 1994, Pages 165-174

  Taticek, Ronald A ^a   Lee, Carolyn WT ^a   Shuler, Michael L ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Chinese hamster ovary; CHO; KLa; mass transfer coefficient; MOL; multiplicity of infection; packed celi volume; PCV; Sf; Spodoptera frugiperda

Indexed keywords

PACLITAXEL; PROTEIN; VINDOLINE;

BIOREACTOR; BIOTECHNOLOGY; CELL CULTURE; CELL DENSITY; CELL METABOLISM; CONTINUOUS CULTURE; CULTURE MEDIUM; INSECT; NONHUMAN; NUTRIENT; OXYGEN SUPPLY; PLANT CELL; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; REVIEW;

ANIMAL; BIOTECHNOLOGY; CELL DIVISION; CELLS, CULTURED; CULTURE MEDIA; INSECTS; MODELS, BIOLOGICAL; PLANTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; RHEOLOGY; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TECHNOLOGY, PHARMACEUTICAL; TISSUE CULTURE; VIRUS CULTIVATION; VISCOSITY;

EID: 0028296334     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-1669(05)80031-X     Document Type: Article

References (48)

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2. Quantification of Cell Culture Factors Affecting Recombinant Protein Yields in Baculovirus-Infected Insect Cells
3. Recombinant β-Galactosidase Production in Serum-Free Medium by Insect Cells in a 14-L Airlift Bioreactor
4. Effect of Temperature and Oxygen on Cell Growth and Recombinant Protein Production in Insect Cell Cultures
5. Production of Recombinant Proteins in High-Density Insect Cell Cultures
6. Optimization of the Production of Full-Length rCD4 in Baculovirus-Infected sf9 Cells
7. Effects of Oxygen/Glucose/Glutamine Feeding on Insect Cell Baculovirus Protein Expression: A Study on Epoxide Hydrolase Production
8. Expression of Epoxide Hydrolase in Insect Cells: A Focus on the Infected Cell
9. Effects of Oxygen on Recombinant Protein Production by Suspension Cultures of Spodoptera frugiperda (Sf-9) Insect Cells
10. Utilization of Glucose and Amino Acids in Insect Cell Cultures: Quantifying the Metabolic Flows within the Primary Pathways and Medium Development
11. A Structured Dynamic Model for the Baculovirus Infection Proccss in Insect-Cell Reactor Configurations
12. Modeling the Population Dynamics of Baculovirus-Infected Insect Cells: Optimizing Infection Strategies for Enhanced Recombinant Protein Yields
13. Modelling the Growth and Protein Production by Insect Cells Following Infection by a Recombinant Baculovirus in Suspension Culture
14. Expression of the Human Multidrug Transporter in Insect Cells by a Recombinant Baculovirus
15. Purification and Characterization of the Recombinant Extracellular Domain of Human Nerve Growth Factor Receptor Expressed in a Baculovirus System
16. 2+ Exchanger in Insect Cells using a Baculovirus Vector
17. Comparison of Soluble and Secreted Forms of Human Parainfluenza Virus Type 3 Glycoproteins Expressed from Mammalian and Insect Cells as Subunit Vaccines
18. Comparison of Oligosaccharide Processing among Various Insect Cell Lincs Expressing Secreted Glycoprotein
19. One-Step Purification and Characterization of Human Pancreatic Lipase Expressed in Insect Cells
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21. Oligosaccharide Processing in the Expression of Human Plasminogen cDNA by Lepidopteran Insect (Spodoptera frugiperda) Cells
22. Temporal Nature of the Promoter and Not Relative Strength Determines the Expression of an Extensively Processed Protein in a Baculovirus System
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24. Structures of the Asparagine-289-Linked Oligosaccharides Assembled on Recombinant Human Plasminogen Expressed in a Mamestra brassicae Cell Line (IZD-MBO503)
25. .alpha.-Mannosidase-catalyzed trimming of high-mannose glycans in noninfected and baculovirus-infected Spodoptera frugiperda cells (IPLB-SF-21AE). A possible contributing regulatory mechanism for assembly of complex-type oligosaccharides in infected cells
26. Environmental Effects on Protein Glycosylation
27. Comparative Recombinant Protein Production of Eight Insect Cell Lines
28. Insect Cell Hosts for Baculovirus Expression Vectors Contain Endogenous Exoglycosidase Activity
29. Induction of Ajmalicine Formation and Related Enzyme Activities in Catharanthus roseus Cells: Effect of Inoculum Density
30. Perfusion Strategy for Rosmarinic Acid Production by Anchusa officinalis
31. Improvement of shikonin productivity inLithospermum erythrorhizon cell culture by alternating carbon and nitrogen feeding strategy
32. Enhanced Recovery of Solavectionc from Agrobacterium Transformed Root Cultures of Hyoscyamus muticus using Integrated Product Extraction
33. Increased Shikonin Production by Hairy Roots of Lithospermum erythrorbizon in Two Phase Bubble Column Reactor
34. Effect of Polymeric Adsorbents on the Production of Sanguinarine by Papaver somniferum Cell Cultures
35. Plant Cell Biotechnology for the Production of Alkaloids: Pressent Status and Prospects
36. Rheological Characteristics of Cell Suspension and Cell Cultures of Perilla frutescens
37. Plant cell suspension culture rheology
38. Rheological Properties of Plant Cell Suspensions
39. Effects of Hydrodynamic Stress on Cultured Plant Cells: A Literature Survey
40. Scaleup of Ajmalicine Production by Plant Cell Cultures of Catharanthus roseus
41. Bioreactor Studies on the Effect of Dissolved Oxygen Concentrations on Growth and Differentiation of Carrot (Daucus carota L.) Cell Cultures
42. Kinetics and Stoichiometry of Growth of Plant Cell Cultures of Catharanthus roseus and Nicotiana tabacum in Batch and Continuous Fermentors
43. A Structured Model Describing Carbon and Phosphate Limited Growth of Catharanthus roseus Plant Cell Suspensions in Batch and Chemostat Culture
44. The Taxol Supply Crisis. New NCI Policies for Handling the Large-Scale Production of Novel Natural Product Anticancer and Anti-HIV Agents
45. Cell Culture of Taxus as a Source of the Antineoplastic Drug Taxol and Related Taxanes
46. Improved Growth and Taxol Yield in Developing Calli of Taxus cuspidata by Medium Composition Modification
47. Production of Indole Alkaloids by Selected Hairy Root Lines of Catharanthus roseus
48. High-Yield Formation of Arbutin from Hydroquinone by Cell-Suspension Cultures ofRauwolfia serpentina