Antitumor Agents. 150. 2′,3′,4′,5′,5,6,7-Substituted 2-Phenyl-4-quinolones and Related Compounds: Their Synthesis, Cytotoxicity, and Inhibition of Tubulin Polymerization

Journal of Medicinal Chemistry

Volumn 37, Issue 8, 1994, Pages 1126-1135

  Li, Leping ^a,b,c,d,e   Wang, Hui Kang ^a,b,c,d,e   Kuo, Sheng Chu ^a,b,c,d,f   Tian Shung, Wu ^a,b,c,d   Lednicer, Dan ^a,b,c,d,g   Lin, Chii M ^a,b,c,d,g   Hamel, Ernest ^a,b,c,d,g   Lee, Kuo Hsiung ^a,b,c,d,e  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d NATIONAL CANCER INSTITUTE   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

^f China Medical College   (China)

^g NCI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYL 4 QUINOLONE DERIVATIVE; 2' CHLORO 6,7 (METHYLENEDIOXY) 2 PHENYL 4 QUINOLONE; 2' FLUORO 6,7 (METHYLENEDIOXY) 2 PHENYL 4 QUINOLONE; 3' (N,N DIMETHYLAMINO) 6 METHOXY 2 PHENYL 4 QUINOLONE; 3' (N,N DIMETHYLAMINO) 6,7 (METHYLENEDIOXY) 2 PHENYL 4 QUINOLONE; 3' METHOXY 6,7 (METHYLENEDIOXY) 2 PHENYL 4 QUINOLONE; 3',5' DIMETHOXY 6,7 (METHYLENEDIOXY) 2 PHENYL 4 QUINOLONE; 3',6 DIMETHOXY 2 PHENYL 4 QUINOLONE; 6,7 (METHYLENEDIOXY) 2 PHENYL 4 QUINOLONE; ANTINEOPLASTIC AGENT; COLCHICINE; COMBRETASTATIN A2; COMBRETASTATIN A4; PODOPHYLLOTOXIN; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

EID: 0028295948     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00034a010     Document Type: Article

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