-
1
-
-
0027161398
-
Complex formation between Ras and Raf and other protein kinases
-
Aelst, L. V., M. Barr, S. Marcus, A. Polverino, and M. Wigler. 1993. Complex formation between Ras and Raf and other protein kinases. Proc. Natl. Acad. Sci. USA 90:6213-6217.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6213-6217
-
-
Aelst, L.V.1
Barr, M.2
Marcus, S.3
Polverino, A.4
Wigler, M.5
-
2
-
-
0025871767
-
Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation
-
Alvarez, E., I. C. Northwood, F. A. Gonzales, D. A. Latour, A. Seth, C. Abate, T. Curma, and R. J. Davis. 1991. Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation. J. Biol. Chem. 266:15277-15285.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 15277-15285
-
-
Alvarez, E.1
Northwood, I.C.2
Gonzales, F.A.3
Latour, D.A.4
Seth, A.5
Abate, C.6
Curma, T.7
Davis, R.J.8
-
3
-
-
0021750054
-
Inositol trisphosphate, a novel second messenger in cellular signal transduction
-
Berridge, M. J., and R. F. Irvine. 1984. Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature (London) 312:315-321.
-
(1984)
Nature (London)
, vol.312
, pp. 315-321
-
-
Berridge, M.J.1
Irvine, R.F.2
-
4
-
-
0026722913
-
q/11, and phospholipase C-β1
-
q/11, and phospholipase C-β1. J. Biol. Chem. 267:8081-8088.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 8081-8088
-
-
Berstein, G.1
Blank, J.L.2
Smrcka, A.V.3
Higashijima, T.4
Sternweis, P.C.5
Exton, J.H.6
Ross, E.M.7
-
6
-
-
0027501802
-
cAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor
-
Burgering, B. M. T., G. J. Pronk, P. C. Weeren, P. Chardin, and J. L. Bos. 1993. cAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor. EMBO J. 12:4211-4220.
-
(1993)
EMBO J.
, vol.12
, pp. 4211-4220
-
-
Burgering, B.M.T.1
Pronk, G.J.2
Weeren, P.C.3
Chardin, P.4
Bos, J.L.5
-
7
-
-
0027200238
-
i-α and specific suppression of type 2 adenylyl cyclase inhibition by phorbol ester treatment
-
i-α and specific suppression of type 2 adenylyl cyclase inhibition by phorbol ester treatment. J. Biol. Chem. 268:12253-12256.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12253-12256
-
-
Chen, J.1
Iyengar, R.2
-
8
-
-
0022628244
-
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase
-
Cheng, H.-C., B. E. Kemp, R. B. Pearson, A. J. Smith, L. Misconi, S. M. VanPatten, and D. A. Walsh. 1986. A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. J. Biol. Chem. 261:989-992.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 989-992
-
-
Cheng, H.-C.1
Kemp, B.E.2
Pearson, R.B.3
Smith, A.J.4
Misconi, L.5
VanPatten, S.M.6
Walsh, D.A.7
-
9
-
-
0026771948
-
Calcium and muscarinic agonist stimulation of type I adenylyl cyclase in whole cells
-
Choi, E.-J., S. T. Wong, T. R. Hinds, and D. R. Storm. 1992. Calcium and muscarinic agonist stimulation of type I adenylyl cyclase in whole cells. J. Biol. Chem. 267:12440-12442.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12440-12442
-
-
Choi, E.-J.1
Wong, S.T.2
Hinds, T.R.3
Storm, D.R.4
-
10
-
-
0027716596
-
Inhibition by cAMP of Ras-dependent activation of Raf
-
Cook, S. J., and F. McCormick. 1993. Inhibition by cAMP of Ras-dependent activation of Raf. Science 262:1069-1072.
-
(1993)
Science
, vol.262
, pp. 1069-1072
-
-
Cook, S.J.1
McCormick, F.2
-
11
-
-
0026539931
-
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
-
Crews, C. M., A. Alessandrini, and R. L. Erikson. 1992. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science 258:478-480.
-
(1992)
Science
, vol.258
, pp. 478-480
-
-
Crews, C.M.1
Alessandrini, A.2
Erikson, R.L.3
-
12
-
-
0026050872
-
Biophysical properties and microfilament assembly in neutrophils: Modulation by cyclic AMP
-
Downey, G. P., E. L. Elson, B. Schwab III, S. C. Eruzman, S. K. Young, and G. S. Worthen. 1991. Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP. J. Cell Biol. 114:1179-1190.
-
(1991)
J. Cell Biol.
, vol.114
, pp. 1179-1190
-
-
Downey, G.P.1
Elson, E.L.2
Schwab III, B.3
Eruzman, S.C.4
Young, S.K.5
Worthen, G.S.6
-
13
-
-
0024391059
-
A transfected m1 muscarinic acetylcholine receptor stimulates adenylate cyclase via phosphatidylinositol hydrolysis
-
Felder, C. C., R. Y. Kanterman, A. L. Ma, and J. Axelrod. 1989. A transfected m1 muscarinic acetylcholine receptor stimulates adenylate cyclase via phosphatidylinositol hydrolysis. J. Biol. Chem. 264:20356-20362.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 20356-20362
-
-
Felder, C.C.1
Kanterman, R.Y.2
Ma, A.L.3
Axelrod, J.4
-
14
-
-
0027171138
-
Activation of mitogen activated kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins
-
Gardner, A. M., R. R. Vaillancourt, and G. L. Johnson. 1993. Activation of mitogen activated kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins. J. Biol. Chem. 268:17896-17901.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17896-17901
-
-
Gardner, A.M.1
Vaillancourt, R.R.2
Johnson, G.L.3
-
15
-
-
0027374550
-
Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells
-
Graves, L. E., K. E. Bornfeldt, E. W. Raines, B. C. Potts, S. G. MacDonald, R. Ross, and E. G. Krebs. 1993. Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc. Natl. Acad. Sci. USA 90:10300-10304.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10300-10304
-
-
Graves, L.E.1
Bornfeldt, K.E.2
Raines, E.W.3
Potts, B.C.4
MacDonald, S.G.5
Ross, R.6
Krebs, E.G.7
-
16
-
-
0026640629
-
MAP kinase is constitutively activated in gip2 and src transformed Rat 1a fibroblasts
-
Gupta, S. K., C. Gallego, G. L. Johnson, and L. E. Heasley. 1992. MAP kinase is constitutively activated in gip2 and src transformed Rat 1a fibroblasts. J. Biol. Chem. 267:7987-7990.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 7987-7990
-
-
Gupta, S.K.1
Gallego, C.2
Johnson, G.L.3
Heasley, L.E.4
-
18
-
-
0024559229
-
Detection of nerve growth factor and epidermal growth factor regulated protein kinases in PC12 cells with synthetic peptide substrates
-
Heasley, L. E., and G. L. Johnson. 1989. Detection of nerve growth factor and epidermal growth factor regulated protein kinases in PC12 cells with synthetic peptide substrates. Mol. Pharmacol. 35:331-338.
-
(1989)
Mol. Pharmacol.
, vol.35
, pp. 331-338
-
-
Heasley, L.E.1
Johnson, G.L.2
-
20
-
-
0026664293
-
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor β subunit
-
Kazlauskas, A., A. Kashishian, J. A. Cooper, and M. Valius. 1992. GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor β subunit. Mol. Cell. Biol. 12:2534-2544.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2534-2544
-
-
Kazlauskas, A.1
Kashishian, A.2
Cooper, J.A.3
Valius, M.4
-
21
-
-
0017638132
-
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase
-
Kemp, B. E., D. J. Graves, E. Benjamini, and E. G. Krebs. 1977. Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase. J. Biol. Chem. 252:4888-4894.
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 4888-4894
-
-
Kemp, B.E.1
Graves, D.J.2
Benjamini, E.3
Krebs, E.G.4
-
22
-
-
0026647749
-
Raf-1 activates MAP kinase-kinase
-
Kyriakis, J. M., H. App, X.-F. Zhang, P. Banerjee, D. L. Bruatigan, U. R. Rapp, and J. Avruch. 1992. Raf-1 activates MAP kinase-kinase. Nature (London) 358:417-421.
-
(1992)
Nature (London)
, vol.358
, pp. 417-421
-
-
Kyriakis, J.M.1
App, H.2
Zhang, X.-F.3
Banerjee, P.4
Bruatigan, D.L.5
Rapp, U.R.6
Avruch, J.7
-
23
-
-
0027215820
-
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
-
Lange-Carter, C., C. Pleiman, A. M. Gardner, K. J. Blumer, and G. L. Johnson. 1993. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science 260:315-319.
-
(1993)
Science
, vol.260
, pp. 315-319
-
-
Lange-Carter, C.1
Pleiman, C.2
Gardner, A.M.3
Blumer, K.J.4
Johnson, G.L.5
-
24
-
-
0026086012
-
Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells
-
Parker, E. M., K. Kameyama, T. Higashijima, and E. M. Ross. 1991. Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells. J. Biol. Chem. 266:519-527.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 519-527
-
-
Parker, E.M.1
Kameyama, K.2
Higashijima, T.3
Ross, E.M.4
-
25
-
-
0026941991
-
Phosphatidylinositol 3-kinase: A novel effector
-
Parker, P. J., and M. D. Waterfield. 1992. Phosphatidylinositol 3-kinase: a novel effector. Cell Growth Differ. 3:747-752.
-
(1992)
Cell Growth Differ.
, vol.3
, pp. 747-752
-
-
Parker, P.J.1
Waterfield, M.D.2
-
26
-
-
0027335583
-
q α subunits: Expression of GTPase-deficient α subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetycholine receptor
-
q α subunits: expression of GTPase-deficient α subunits persistently stimulates phosphatidylinositol-specific phospholipase C but not mitogen-activated protein kinase activity regulated by the M1 muscarinic acetycholine receptor. Proc. Natl. Acad. Sci. USA 90:4077-4081.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4077-4081
-
-
Qian, N.-X.1
Winitz, S.2
Johnson, G.L.3
-
28
-
-
0027485031
-
Increasing cAMP attenuates activation of mitogen-activated protein kinase
-
Sevetson, B. R., X. Kong, and J. C. Lawrence, Jr. 1993. Increasing cAMP attenuates activation of mitogen-activated protein kinase. Proc. Natl. Acad. Sci. USA 90:10305-10309.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10305-10309
-
-
Sevetson, B.R.1
Kong, X.2
Lawrence Jr., J.C.3
-
29
-
-
0027285860
-
Receptor stimulated accumulation of phosphatidyl (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells
-
Stephens, L., A. Eguinoa, S. Corey, T. Jackson, and P. T. Hawkins. 1993. Receptor stimulated accumulation of phosphatidyl (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells. EMBO J. 12:2265-2273.
-
(1993)
EMBO J.
, vol.12
, pp. 2265-2273
-
-
Stephens, L.1
Eguinoa, A.2
Corey, S.3
Jackson, T.4
Hawkins, P.T.5
-
30
-
-
0027260461
-
Synthesis of phosphatidylinositol 3,4,5-trisphosphate in permeabilized neutrophils regulated by receptors and G-proteins
-
Stephens, L., T. Jackson, and P. T. Hawkins. 1993. Synthesis of phosphatidylinositol 3,4,5-trisphosphate in permeabilized neutrophils regulated by receptors and G-proteins. J. Biol. Chem. 268:17162-17172.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17162-17172
-
-
Stephens, L.1
Jackson, T.2
Hawkins, P.T.3
-
31
-
-
0026715160
-
95-kilodalton B-Raf serine/threonine kinase: Identification of the protein and its major phosphorylation site
-
Stephens, R. M., G. Sithanandam, T. D. Copeland, D. R. Kaplan, U. R. Rapp, and D. K. Morrison. 1992. 95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major phosphorylation site. Mol. Cell. Biol. 12:3733-3742.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 3733-3742
-
-
Stephens, R.M.1
Sithanandam, G.2
Copeland, T.D.3
Kaplan, D.R.4
Rapp, U.R.5
Morrison, D.K.6
-
32
-
-
0026785920
-
Adenylyl cyclases
-
Tang, W.-J., and A. G. Gilman. 1992. Adenylyl cyclases. Cell 70:869-872.
-
(1992)
Cell
, vol.70
, pp. 869-872
-
-
Tang, W.-J.1
Gilman, A.G.2
-
33
-
-
0023621276
-
Inositol 1,4,5-trisphosphate and inositol 1,2-cyclic 4,5-trisphosphate are minor components of total mass of inositol trisphosphate in thrombin stimulated platelets
-
Tarver, A. P., W. G. King, and S. E. Rittenhouse. 1987. Inositol 1,4,5-trisphosphate and inositol 1,2-cyclic 4,5-trisphosphate are minor components of total mass of inositol trisphosphate in thrombin stimulated platelets. J. Biol. Chem. 262:17268-17271.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 17268-17271
-
-
Tarver, A.P.1
King, W.G.2
Rittenhouse, S.E.3
-
34
-
-
0027211693
-
Phospholipase Cγ (PLCγ) and phosphatidylinositol 3 kinase (PI3K) are the downstream mediators of the PDGF receptor's mitogenic signal
-
Valius, M., and A. Kazlauskas. 1993. Phospholipase Cγ (PLCγ) and phosphatidylinositol 3 kinase (PI3K) are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73:321-329.
-
(1993)
Cell
, vol.73
, pp. 321-329
-
-
Valius, M.1
Kazlauskas, A.2
-
35
-
-
0027250250
-
Mammalian Ras interacts directly with the serine/threonine kinase Raf
-
Vojtek, A. B., S. M. Hollenberg, and J. A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74:205-214.
-
(1993)
Cell
, vol.74
, pp. 205-214
-
-
Vojtek, A.B.1
Hollenberg, S.M.2
Cooper, J.A.3
-
36
-
-
0027200883
-
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
-
Warne, P. H., P. R. Viciana, and J. Downward. 1993. Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro. Nature (London) 364:352-355.
-
(1993)
Nature (London)
, vol.364
, pp. 352-355
-
-
Warne, P.H.1
Viciana, P.R.2
Downward, J.3
-
37
-
-
0027240231
-
i-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase
-
i-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase. J. Biol. Chem. 268:19196-19199.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19196-19199
-
-
Winitz, S.1
Russell, M.2
Qian, N.-X.3
Dwyer, L.4
Johnson, G.L.5
-
39
-
-
0027772672
-
Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphates
-
Wu, J., P. Dent, T. Jelinek, A. Wolfman, M. J. Weber, and T. W. Sturgill. 1993. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphates. Science 262:1065-1069.
-
(1993)
Science
, vol.262
, pp. 1065-1069
-
-
Wu, J.1
Dent, P.2
Jelinek, T.3
Wolfman, A.4
Weber, M.J.5
Sturgill, T.W.6
-
40
-
-
0027337248
-
ras proteins bind to the aminoterminal regulatory domain of c-Raf-1
-
ras proteins bind to the aminoterminal regulatory domain of c-Raf-1. Nature (London) 364:308-313.
-
(1993)
Nature (London)
, vol.364
, pp. 308-313
-
-
Zhang, X.1
Settleman, J.2
Kyriakis, J.M.3
Takeuchi-Suzuki, E.4
Elledge, J.5
Marshall, M.S.6
Brader, J.T.7
Rapp, U.R.8
Avruch, J.9
|