DP and E2F proteins: components of a heterodimeric transcription factor implicated in cell cycle control

Current Opinion in Cell Biology

Volumn 6, Issue 3, 1994, Pages 443-450

  La Thangue, Nicholas B ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; GENE PRODUCT; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR;

CELL CYCLE; DNA BINDING; DNA TRANSCRIPTION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVIEW; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANIMAL; CELL CYCLE; HUMAN; MOLECULAR SEQUENCE DATA; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 0028292621     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0955-0674(94)90038-8     Document Type: Article

References (42)

1. E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins
2. DRTF1/E2F: An Expanding Group of Heterodimeric Transcription Factors Implicated in Cell Cycle Control
3. An E2F-Binding Site Mediates Cell-Cycle Regulated Repression of Mouse B-myb Transcription
4. The Retinoblastoma Protein and the Regulation of Cell Cycling
5. Adenovirus E1a Prevents the Retinoblastoma Gene Product from Complexing with a Cellular Transcription Factor
6. The E2F Transcription Factor is a Cellular Target for the RB Protein
7. Adenovirus E1A Prevents the Retinoblastoma Gene Product from Repressing the Activity of a Cellular Transcription Factor
8. The Interaction of pRb with E2F Coincides with an Inhibition of the Transcriptional Activity of E2F
9. Identification of Distinct Roles for Separate E1A Domains in Disruption of E2F Complexes
10. Independent Regions of Adenovirus E1A are Required for Binding to and Dissociation of E2F-Protein Complexes
11. Molecular Cloning, Chromosomal Mapping and Expression of the cDNA for p107, a Retinoblastoma Gene Product-Related Protein
12. Cloning of a New Member of the Retinoblastoma Gene Family (pRb2) which Binds to the E1a Transforming Domain
13. The Adenovirus E1A-Associated 130-kD Protein is Encoded by a Member of the Retinoblastoma Gene Family and Physically Interacts with Cyclins A and E
14. Isolation of the Rb-Related p130 Through Its Interaction with CDK2 and Cyclins
15. Cell Cycle-Specific Association of E2F with the p130 E1A-Binding Protein
16. Inhibition of Cell Proliferation by p107, a Relative of the Retinoblastoma Protein
17. The Transcription Factor E2F Interacts with the Retinoblastoma Product and a p107-Cyclin A Complex in a Cell Cycle-Regulated Manner
18. Transcriptional Repression by the Rb-Related Protein p107
19. Interactions of the p107 and Rb Proteins with E2F During the Cell Proliferation Response
20. Regulation of Retinoblastoma Protein Functions by Ectopic Expression of Human Cyclins
21. Cyclin E/cdk2 and Cyclin A/cdk2 Kinases Associate with p107 and E2F in a Temporally Distinct Matter
22. cdk2 is a Component of the E2F-Cyclin A Complex
23. Independent Binding of the Retinoblastoma Protein and p107 to the Transcription Factor E2F
24. A cDNA Encoding a pRB-Binding Protein with Properties of the Transcription Factor E2F
25. Expression Cloning of a cDNA Encoding a Retinoblastoma-Binding Protein with E2F-Like Properties
26. Molecular Cloning of Cellular Genes Encoding Retinoblastoma-Associated Proteins: Identification of a Gene with Properties of the Transcription Factor E2F
27. Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein
28. E2F-1 Mediated Transactivation is Inhibited by Complex Formation with the Retinoblastoma Susceptibility Gene Product
29. The Activation Domain of Transcription Factor PU.1 Binds the Retinoblastoma (RB) Protein and Transcription Factor TFIID in Vitro: RB Shows Sequence Similarity to TFIID and TFIIB
30. The Retinoblastoma Protein Binds: E2F Residues Required for Activation in Vivo and TBP Binding in Vitro
31. A New Component of the Transcription Factor DRTF1/E2F
32. Cell Cycle Analysis of E2F in Primary Human T Cells Reveals Novel E2F Complexes and Biochemically Distinct Forms of Free E2F
33. A Protein Synthesis-Dependent Increase in E2F1 mRNA Correlates with Growth Regulation of the Dihydrofolate Reductase Promoter
34. Expression of E2F1 Induces Quiescent Cells to Enter S Phase
35. Functional Synergy Between DP-1 and E2F-1 in the Cell Cycle-Regulating Transcription Factor DRTF1/E2F
36. Heterodimerization of the Transcription Factors E2F-1 and DP-1 Leads to Cooperative Transactivation
37. Binding to DNA and the Retinoblastoma Gene Product Promoted by Complex Formation of Different E2F Family Members
38. Transcription Factor E2F Binds DNA as a Heterodimer
39. Cloning and Characterization of E2F-2, a Novel Protein with the Biochemical Properties of Transcription Factor E2F
40. The Retinoblastoma Protein Binds to a Family of E2F Transcription Factors
41. Analysis of p107-Associated Proteins: p107 Associates with a Form of E2F that Differs from pRb-Associated E2F-1
42. Mammalian G1 Cyclins