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Volumn 6, Issue 4, 1994, Pages 348-356

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; RNA;

EID: 0028292605     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng0494-348     Document Type: Article
Times cited : (1064)

References (61)
  • 1
    • 0024574583 scopus 로고
    • A new family of mouse homeo box-containing genes: Molecular structure chromosomal location & developmental expression ofHox-7. 1
    • Hill, R. E. et al. A new family of mouse homeo box-containing genes: molecular structure chromosomal location & developmental expression ofHox-7. 1. Genes Dev. 3, 26-37 (1989).
    • (1989) Genes Dev , vol.3 , pp. 26-37
    • Hill, R.E.1
  • 2
    • 0024452548 scopus 로고
    • >Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis
    • Robert, B., Sassoon, D., Jacq, B., Gehring, W. & Buckingham, M. >Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis. EMBO J. 8, 91-100 (1989).
    • (1989) EMBO J , vol.8 , pp. 91-100
    • Robert, B.1    Sassoon, D.2    Jacq, B.3    Gehring, W.4    Buckingham, M.5
  • 3
    • 0343433972 scopus 로고
    • The homeobox: Structural and evolutionary aspects
    • (eds Firtel, R. A. & Davidson, E. H.) (Liss, New York)
    • Gehring, W. J. The homeobox: Structural and evolutionary aspects, inMolecular Approaches toDevelopmental Biology (eds Firtel, R. A. & Davidson, E. H.) 115-129 (Liss, New York, 1987).
    • (1987) Molecular Approaches toDevelopmental Biology , pp. 115-129
    • Gehring, W.J.1
  • 4
    • 0026100213 scopus 로고
    • Cloning and evolutionary analysis of msh like homeobox genes from mouse, zebrafish and ascidian
    • Holland, P. W. H. Cloning and evolutionary analysis of msh like homeobox genes from mouse, zebrafish and ascidian. Gene 98, 253-257 (1991).
    • (1991) Gene , vol.98 , pp. 253-257
    • Holland, P.W.H.1
  • 5
    • 0025743150 scopus 로고
    • The Msh -like homeobox genes define domains in the developing vertebrate eye
    • Monaghan, A. P. et al. The Msh -like homeobox genes define domains in the developing vertebrate eye. Development 112, 1053-1061 (1991).
    • (1991) Development , vol.112 , pp. 1053-1061
    • Monaghan, A.P.1
  • 6
    • 0027251351 scopus 로고
    • Genomic structure, chromosomal location, and evolution of the mouse Hox-8 gene
    • 17 800
    • Bell, J. R. et al. Genomic structure, chromosomal location, and evolution of the mouse Hox-8 gene. Genomics 16, 123-131 and 17, 800 (1993).
    • (1993) Genomics , vol.16 , pp. 123-131
    • Bell, J.R.1
  • 7
    • 0025361004 scopus 로고
    • The human homeobox gene Hox7 maps chromosome 4p16. 1 and may be implicated in Wolf-Hirschhorn syndrome
    • Ivens, A. et al. The human homeobox gene Hox7 maps chromosome 4p16. 1 and may be implicated in Wolf-Hirschhorn syndrome. Human Genet. 84, 473-476 (1990).
    • (1990) Human Genet , vol.84 , pp. 473-476
    • Ivens, A.1
  • 8
    • 0026043763 scopus 로고
    • Structure and sequence of the human homeobox gene Hox7
    • Hewitt, J. E., Clark, L. N., Ivens, A. & Williamson, R. Structure and sequence of the human homeobox gene Hox7. Genomics 11, 670-678 (1991).
    • (1991) Genomics , vol.11 , pp. 670-678
    • Hewitt, J.E.1    Clark, L.N.2    Ivens, A.3    Williamson, R.4
  • 9
    • 0027431005 scopus 로고
    • A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis
    • Jabs, E. W. et al. A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell 75, 443-450 (1993).
    • (1993) Cell , vol.75 , pp. 443-450
    • Jabs, E.W.1
  • 10
    • 0025979545 scopus 로고
    • The homeobox gene Hox7. 1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro
    • MacKenzie, A., Leeming, G. L., Jowett, A. K., Ferguson, M. W. J. & Sharpe, P. T. The homeobox gene Hox7. 1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. Development 111, 269-285 (1991).
    • (1991) Development , vol.111 , pp. 269-285
    • MacKenzie, A.1    Leeming, G.L.2    Jowett, A.K.3    Ferguson, M.W.J.4    Sharpe, P.T.5
  • 11
    • 0026056188 scopus 로고
    • Hox-7 expression during murine craniofacial development
    • MacKenzie, A., Ferguson, M. W. J. & Sharpe, P. T. Hox-7 expression during murine craniofacial development. Development 113, 601-611 (1991).
    • (1991) Development , vol.113 , pp. 601-611
    • MacKenzie, A.1    Ferguson, M.W.J.2    Sharpe, P.T.3
  • 12
    • 0026762590 scopus 로고
    • Expression patterns of the homeobox gene Hox 8 in the mouse embryo suggest a role in specifying tooth initiation and shape
    • MacKenzie, A., Ferguson, M. W. J. & Sharpe, P. T. Expression patterns of the homeobox gene Hox 8 in the mouse embryo suggest a role in specifying tooth initiation and shape. Development 115, 403-420 (1992).
    • (1992) Development , vol.115 , pp. 403-420
    • MacKenzie, A.1    Ferguson, M.W.J.2    Sharpe, P.T.3
  • 13
    • 0026049132 scopus 로고
    • Repeating developmental expression of G-Hox7, a novel homeobox-containing gene in the chicken
    • Suzuki, H. R., Padanilam, B. J., Vitale, E., Ramirez, F. & Solursh, M. Repeating developmental expression of G-Hox7, a novel homeobox-containing gene in the chicken. Dev. Biol. 148, 375-388 (1991).
    • (1991) Dev. Biol , vol.148 , pp. 375-388
    • Suzuki, H.R.1    Padanilam, B.J.2    Vitale, E.3    Ramirez, F.4    Solursh, M.5
  • 14
    • 0026717624 scopus 로고
    • Multiple sites of Hox-7 expression during mouse embryogenesis: Comparison with retinoic acid receptor mRNA localization
    • Lyons, G. E., Houzelstein, D., Sassoon, D., Robert, B. & Buckingham, M. Multiple sites of Hox-7 expression during mouse embryogenesis: comparison with retinoic acid receptor mRNA localization. Molec. repro. Dev. 32, 303-314(1992).
    • (1992) Molec. repro. Dev , vol.32 , pp. 303-314
    • Lyons, G.E.1    Houzelstein, D.2    Sassoon, D.3    Robert, B.4    Buckingham, M.5
  • 15
    • 0027433502 scopus 로고
    • Expression of homeobox genes Msx-1 (Hox-7) and Msx-2 (Hox-8) during cardiac development in chick
    • Chan-Thomas, P. S., Thompson, R. P., Robert, B., Yacoub, M. H. & Barton, P. J. R. Expression of homeobox genes Msx-1 (Hox-7) and Msx-2 (Hox-8) during cardiac development in chick. Develop. Dyn. 197, 203-216 (1993).
    • (1993) Develop. Dyn , vol.197 , pp. 203-216
    • Chan-Thomas, P.S.1    Thompson, R.P.2    Robert, B.3    Yacoub, M.H.4    Barton, P.J.R.5
  • 16
    • 0026267740 scopus 로고
    • The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds
    • Robert, B., Lyons, G., Simandl, B. K., Kuroiwa, A. & Buckingham, M. The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes Dev. 5, 2363-2374 (1991).
    • (1991) Genes Dev , vol.5 , pp. 2363-2374
    • Robert, B.1    Lyons, G.2    Simandl, B.K.3    Kuroiwa, A.4    Buckingham, M.5
  • 17
    • 0025787003 scopus 로고
    • Position dependent expression of two related homeobox genes in developing vertebrate limbs
    • Davidson, D. R., Crawley, A., Hill, R. E. & Tickle, C. Position dependent expression of two related homeobox genes in developing vertebrate limbs. Nature 352, 429-431 (1991).
    • (1991) Nature , vol.352 , pp. 429-431
    • Davidson, D.R.1    Crawley, A.2    Hill, R.E.3    Tickle, C.4
  • 18
    • 0026315619 scopus 로고
    • Altered expression of the chicken homeobox-containing gene GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos
    • Coelho, C. N. D., Krabbenhoft, K. M., Upholt, W. B., Fallon, J. F. & Kosher, R. A. Altered expression of the chicken homeobox-containing gene GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos. Development 113, 1487-1493 (1991).
    • (1991) Development , vol.113 , pp. 1487-1493
    • Coelho, C.N.D.1    Krabbenhoft, K.M.2    Upholt, W.B.3    Fallon, J.F.4    Kosher, R.A.5
  • 19
    • 0026708381 scopus 로고
    • Role of the chicken homeobox-containing genes GHox-4. 6 and GHox-8 in the specification of positional identities during the development of normal and polydactylous chick limb buds
    • Coelho, C. N. D., Upholt, W. B. & Kosher, R. A. Role of the chicken homeobox-containing genes GHox-4. 6 and GHox-8 in the specification of positional identities during the development of normal and polydactylous chick limb buds. Development 115, 629-637 (1992).
    • (1992) Development , vol.115 , pp. 629-637
    • Coelho, C.N.D.1    Upholt, W.B.2    Kosher, R.A.3
  • 20
    • 0026470925 scopus 로고
    • Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds
    • Ros, M. A. et al. Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds. Development 116, 811-818 (1992).
    • (1992) Development , vol.116 , pp. 811-818
    • Ros, M.A.1
  • 21
    • 0027326880 scopus 로고
    • Experimental analysis of the control of expression of the homeobox-gene Msx-1 in the developing limb and face
    • Brown, J. M. et al. Experimental analysis of the control of expression of the homeobox-gene Msx-1 in the developing limb and face. Development 119, 41-48 (1993).
    • (1993) Development , vol.119 , pp. 41-48
    • Brown, J.M.1
  • 22
    • 0025815196 scopus 로고
    • Epithelio-mesenchymal interactions are critical for Quox 7 expression and membrane bone differentiation in the neural crest derived mandibular mesenchyme
    • Takahashi, Y., Bontoux, M. & Le Douarin, N. M. Epithelio-mesenchymal interactions are critical for Quox 7 expression and membrane bone differentiation in the neural crest derived mandibular mesenchyme. EMBOJ. 10, 2387-2393(1991).
    • (1991) EMBOJ , vol.10 , pp. 2387-2393
    • Takahashi, Y.1    Bontoux, M.2    Le Douarin, N.M.3
  • 23
    • 0027467238 scopus 로고
    • Epithelial-mesenchymal interactions are required for msx1 and msx2 gene expression in the developing murine molar tooth
    • Jowett, A. K., Vainio, S., Ferguson, M. W. J., Sharpe, P. T. & Thesleff, I. Epithelial-mesenchymal interactions are required for msx1 and msx2 gene expression in the developing murine molar tooth. Development 117, 461-470(1993).
    • (1993) Development , vol.117 , pp. 461-470
    • Jowett, A.K.1    Vainio, S.2    Ferguson, M.W.J.3    Sharpe, P.T.4    Thesleff, I.5
  • 24
    • 0026447532 scopus 로고
    • A role for Quox-8 in the establishment of the dorsoventral pattern during vertebrate development
    • Takahashi, Y., Monsoro-Burg, A.-H., Bontoux, M. & Le Douarin, N. M. A role for Quox-8 in the establishment of the dorsoventral pattern during vertebrate development. Proc. natn. Acad. Sci. U. S. A. 89, 10237-10241 (1992).
    • (1992) Proc. natn. Acad. Sci. U. S. A , vol.89 , pp. 10237-10241
    • Takahashi, Y.1    Monsoro-Burg, A.-H.2    Bontoux, M.3    Le Douarin, N.M.4
  • 25
    • 0000609255 scopus 로고
    • Msh-like genes: A family of homeobox genes with wide ranging expression during vertebrate development
    • Davidson, D. R. & Hill, R. E. Msh-like genes: a family of homeobox genes with wide ranging expression during vertebrate development. Sem. Dev. Biol. 2, 405-412 (1991).
    • (1991) Sem. Dev. Biol , vol.2 , pp. 405-412
    • Davidson, D.R.1    Hill, R.E.2
  • 26
    • 0026780494 scopus 로고
    • Molecular aspects of regeneration in developing vertebrate limbs
    • Muneoka, K. & Sasoon, D. Molecular aspects of regeneration in developing vertebrate limbs. Dev. Biol. 152, 37-49 (1992).
    • (1992) Dev. Biol , vol.152 , pp. 37-49
    • Muneoka, K.1    Sasoon, D.2
  • 27
    • 0026753812 scopus 로고
    • Homeobox genes and pattern formation in the vertebrate limb
    • Izpisúa-Belmonte, J.-C. & Duboule, D. Homeobox genes and pattern formation in the vertebrate limb. Dev. Biol. 152, 26-36 (1992).
    • (1992) Dev. Biol , vol.152 , pp. 26-36
    • Izpisúa-Belmonte, J.-C.1    Duboule, D.2
  • 28
    • 0027180420 scopus 로고
    • Later embryogenesis: Regulatory circuitry in morphogenetic fields
    • Davidson, E. H. Later embryogenesis: regulatory circuitry in morphogenetic fields. Development 118, 665-690 (1993).
    • (1993) Development , vol.118 , pp. 665-690
    • Davidson, E.H.1
  • 29
    • 0027230177 scopus 로고
    • Induction phenomena in vertebrate limb formation and expression of homeobox genes
    • Robert, B. et al. Induction phenomena in vertebrate limb formation and expression of homeobox genes. Ann. Génétique 36, 39-45 (1993).
    • (1993) Ann. Génétique , vol.36 , pp. 39-45
    • Robert, B.1
  • 30
    • 0003868876 scopus 로고
    • Oxford Monograph on Medical genetics No. 19, Third edition. (Oxford University Press, Oxford, England)
    • Gorlin, R. J., Cohen, M. M. Jr., & Levin, L. S. Syndromes of the Head and Neck. Oxford Monograph on Medical genetics No. 19, Third edition. 693-714 (Oxford University Press, Oxford, England, 1990).
    • (1990) Syndromes of the Head and Neck , pp. 693-714
    • Gorlin, R.J.1    Cohen, M.M.2    Levin, L.S.3
  • 31
    • 0022745244 scopus 로고
    • A review of tooth formation in children with cleft lip/palate
    • Ranta, R. A review of tooth formation in children with cleft lip/palate. A. J. Orthod. Dentofac. Orthop. 90, 11-18 (1986).
    • (1986) A. J. Orthod. Dentofac. Orthop , vol.90 , pp. 11-18
    • Ranta, R.1
  • 32
    • 0000813806 scopus 로고
    • Robin and the syndrome that bears his name
    • Randall, P., Krogman, W. M. & Jahina, S., Robin and the syndrome that bears his name. Cleft Palate J. 2, 237-246 (1965).
    • (1965) Cleft Palate J , vol.2 , pp. 237-246
    • Randall, P.1    Krogman, W.M.2    Jahina, S.3
  • 33
    • 0003436550 scopus 로고
    • 8th edn 1138-1139 (Johns Hopkins University Press, Baltimore)
    • McKusick, V. A. Mendelian Inheritance in Man. 8th edn 1138-1139 (Johns Hopkins University Press, Baltimore 1988).
    • (1988) Mendelian Inheritance in Man
    • McKusick, V.A.1
  • 34
    • 0023687125 scopus 로고
    • The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo
    • Couly, G. and Le Douarin, N. M. The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo. Development Supp. 103, 101-113 (1988).
    • (1988) Development Supp , vol.103 , pp. 101-113
    • Couly, G.1    Le Douarin, N.M.2
  • 35
    • 0027415509 scopus 로고
    • The triple origin of skull in higher vertebrates: A study in quail-chick chimeras
    • Couly, G. F., Coltey, P. M. & Le Douarin, N. M. The triple origin of skull in higher vertebrates: a study in quail-chick chimeras. Development 117, 409-429 (1993).
    • (1993) Development , vol.117 , pp. 409-429
    • Couly, G.F.1    Coltey, P.M.2    Le Douarin, N.M.3
  • 36
    • 0023811391 scopus 로고
    • Interactions and fates of avian craniofacial mesenchyme
    • Noden, D. M. Interactions and fates of avian craniofacial mesenchyme. Development Supp. 103, 121-140 (1988).
    • (1988) Development Supp , vol.103 , pp. 121-140
    • Noden, D.M.1
  • 37
    • 0023687127 scopus 로고
    • Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ
    • Lumsden, A. G. S. Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ. Development Supp. 103, 155-169 (1988).
    • (1988) Development Supp , vol.103 , pp. 155-169
    • Lumsden, A.G.S.1
  • 38
    • 0016828772 scopus 로고
    • The neural crest in abnormalities of the face and brain
    • (The National March of Dimes Foundation)
    • Johnston, M. C. The neural crest in abnormalities of the face and brain. Birth Defects: Original Article Series, Vol. Xl(7), 118 (The National March of Dimes Foundation, 1975).
    • (1975) Birth Defects: Original Article Series , vol.11 , Issue.7 , pp. 118
    • Johnston, M.C.1
  • 39
    • 0023761040 scopus 로고
    • Teratogenesis and craniofacial malformations: Relationships to cell death
    • Sulik, K. K., Cook, C. S. & Webster, W. S. Teratogenesis and craniofacial malformations: relationships to cell death. Development Supp. 103, 213-232 (1988).
    • (1988) Development Supp , vol.103 , pp. 213-232
    • Sulik, K.K.1    Cook, C.S.2    Webster, W.S.3
  • 40
    • 0023074096 scopus 로고
    • Development of periodontal ligament and alveolar bone in homografted recombinations of enamel organs and papillary, pulpal and follicular mesenchyme in the mouse
    • Palmer, R. M. & Lumsden, A. G. S. Development of periodontal ligament and alveolar bone in homografted recombinations of enamel organs and papillary, pulpal and follicular mesenchyme in the mouse. Arch. Oral Biol. 32, 281-289 (1987).
    • (1987) Arch. Oral Biol , vol.32 , pp. 281-289
    • Palmer, R.M.1    Lumsden, A.G.S.2
  • 41
    • 0027363024 scopus 로고
    • Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development
    • Vainio, S., Karavanova, I., Jowett, A. & Thesleff, I. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75, 45-58 (1993).
    • (1993) Cell , vol.75 , pp. 45-58
    • Vainio, S.1    Karavanova, I.2    Jowett, A.3    Thesleff, I.4
  • 42
    • 0025770771 scopus 로고
    • Expression of the chicken homeobox-containing gene GHox-8 during embryonic chick limb development
    • Coelho, C. N. D. et al. Expression of the chicken homeobox-containing gene GHox-8 during embryonic chick limb development. Mech. Dev. 34, 143-154 (1991).
    • (1991) Mech. Dev , vol.34 , pp. 143-154
    • Coelho, C.N.D.1
  • 43
    • 0026576114 scopus 로고
    • GHox-7: A chicken homeobox-containing gene expressed in a fashion consistent with a role in patterning events during embryonic chick limb development
    • Coelho, C. N. D., Sumoy, L., Kosher, R. A. & Upholt, W. B., GHox-7: A chicken homeobox-containing gene expressed in a fashion consistent with a role in patterning events during embryonic chick limb development. Differentiation 49, 85-92 (1992).
    • (1992) Differentiation , vol.49 , pp. 85-92
    • Coelho, C.N.D.1    Sumoy, L.2    Kosher, R.A.3    Upholt, W.B.4
  • 44
    • 0023694945 scopus 로고
    • Palate development
    • Ferguson, M. Palate development. Development Supp. 103, 41-60 (1988).
    • (1988) Development Supp , vol.103 , pp. 41-60
    • Ferguson, M.1
  • 45
    • 73049150826 scopus 로고
    • Development of cleft palate in mice homozygous for the shorthead mutation
    • Fitch, N. Development of cleft palate in mice homozygous for the shorthead mutation. J. Morphot. 109, 151-157 (1961).
    • (1961) J. Morphot , vol.109 , pp. 151-157
    • Fitch, N.1
  • 46
    • 0017621961 scopus 로고
    • Mandibular growth retardation as a cause of cleft palate in mice homozygous for the chondrodysplasia gene
    • Seegmiller, R. E. & Fraser, F. C. Mandibular growth retardation as a cause of cleft palate in mice homozygous for the chondrodysplasia gene. J. Embryol. exp. Morph. 38, 227-238 (1977).
    • (1977) J. Embryol. exp. Morph , vol.38 , pp. 227-238
    • Seegmiller, R.E.1    Fraser, F.C.2
  • 47
    • 0021061875 scopus 로고
    • Abnormal facial development in the mouse mutant first arch
    • Juriloff, D. M. & Harris, M. J. Abnormal facial development in the mouse mutant first arch. J. Cranio. Gen. devl. Biol. 3, 317-337 (1983).
    • (1983) J. Cranio. Gen. devl. Biol , vol.3 , pp. 317-337
    • Juriloff, D.M.1    Harris, M.J.2
  • 48
    • 0027258758 scopus 로고
    • 3 subunit of the type Aγ-aminobutyric acid receptor
    • 3 subunit of the type Aγ-aminobutyric acid receptor. Proc. natn. Acad. Sci. U. S. A. 90, 5105-5109(1993).
    • (1993) Proc. natn. Acad. Sci. U. S. A , vol.90 , pp. 5105-5109
    • Culiat, C.T.1
  • 49
    • 0027338402 scopus 로고
    • A cluster of three GABA receptor subunit genes is deleted in a neurological mutant of the mouse p locus
    • Nakatsu, Y. et al. A cluster of three GABA receptor subunit genes is deleted in a neurological mutant of the mouse p locus. Nature 364, 448-450 (1993).
    • (1993) Nature , vol.364 , pp. 448-450
    • Nakatsu, Y.1
  • 50
    • 0027759447 scopus 로고
    • Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest
    • Gendron-Maguire, M. et al. Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell 75, 1317-1331 (1993).
    • (1993) Cell , vol.75 , pp. 1317-1331
    • Gendron-Maguire, M.1
  • 51
    • 0027739813 scopus 로고
    • A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a homeotic selector gene
    • Rijli, F. M. et al. A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a homeotic selector gene. Cell 75, 1333-1349 (1993).
    • (1993) Cell , vol.75 , pp. 1333-1349
    • Rijli, F.M.1
  • 52
    • 0026500144 scopus 로고
    • Familal recurrence-pattern analysis of cleft lip with or without cleft palate
    • Farrall, M. & Holder, S. Familal recurrence-pattern analysis of cleft lip with or without cleft palate. Am. J. hum. Gen. 50, 270-277 (1992).
    • (1992) Am. J. hum. Gen , vol.50 , pp. 270-277
    • Farrall, M.1    Holder, S.2
  • 53
    • 0026641795 scopus 로고
    • Cleft lip with or without cleft palate in Shanghai, China: Evidence for an autosomal major locus
    • Marazita, M. L., Hu, D-N, Spence, M. A., Liu, Y-E., Melnick, M. Cleft lip with or without cleft palate in Shanghai, China: evidence for an autosomal major locus. Am. J. hum. Gen. 51, 648-653 (1992).
    • (1992) Am. J. hum. Gen , vol.51 , pp. 648-653
    • Marazita, M.L.1    Hu, D.-N.2    Spence, M.A.3    Liu, Y.-E.4    Melnick, M.5
  • 55
    • 0026708177 scopus 로고
    • Argeted mutation of the DNA methyl transferase gene results in embryonic lethality
    • Li, E., Bestor, T. & Jaenisch, R. argeted mutation of the DNA methyl transferase gene results in embryonic lethality. Cell 69, 915-926 (1992).
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.2    Jaenisch, R.3
  • 56
    • 0024420342 scopus 로고
    • Germ line transmission of adisrupted β2-microglobulin gene produced by homologous recombination in embryonic stem cells
    • Zijlstra, M., Li, E., Sajjadi, F., Subramani, S. & Jaensich, R. Germ line transmission of adisrupted β2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature 342, 435-438 (1989).
    • (1989) Nature , vol.342 , pp. 435-438
    • Zijlstra, M.1    Li, E.2    Sajjadi, F.3    Subramani, S.4    Jaensich, R.5
  • 58
    • 0023646810 scopus 로고
    • Site directed mutagenesis by gene targeting in mouse embryo derived stem cells
    • Thomas, K. & Capecchi, M. Site directed mutagenesis by gene targeting in mouse embryo derived stem cells. Cell 51, 503-512 (1987).
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.1    Capecchi, M.2
  • 60
    • 0025739379 scopus 로고
    • Simplified mammalian DNA isolation procedure
    • Laird, P. W. et al. Simplified mammalian DNA isolation procedure. Nuc. Acid Res. 19, 4293 (1991).
    • (1991) Nuc. Acid Res , vol.19 , pp. 4293
    • Laird, P.W.1
  • 61
    • 0019126423 scopus 로고
    • Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S
    • McLeod, M. J. Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratology 22, 299-301 (1980).
    • (1980) Teratology , vol.22 , pp. 299-301
    • McLeod, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.