Rachelle fishman matthew moore lecture: The pathological and clinical dynamics of multiple sclerosis

Journal of Neuropathology and Experimental Neurology

Volumn 53, Issue 4, 1994, Pages 338-343

  McDonald, W I ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Degeneration; Demyelination; Evoked potentials; Inflammation; MRI; MRS; Multiple sclerosis

Indexed keywords

SODIUM CHANNEL;

BLOOD BRAIN BARRIER; CONFERENCE PAPER; DEMYELINATION; EDEMA; HUMAN; INFLAMMATION; NERVE CONDUCTION; NERVE DEGENERATION; PATHOGENESIS; PRIORITY JOURNAL; RELAPSE; REMISSION; SYSTEMIC SCLEROSIS;

ELECTROPHYSIOLOGY; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MULTIPLE SCLEROSIS;

EID: 0028291556     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/00005072-199407000-00003     Document Type: Article

References (50)

1. Carswell R. Pathological anatomy. Illustrations of the elementary forms of disease. London: Longman, Orme, Brown, Green and Longman, 1838
2. Cruveilhier J. Anatomie pathologique du corps humain; descriptions avec figures lithographiees et colorizes; des diverses alterations morbides dont le corps humain est susceptible. Paris: J.B. Balliere, 1835-1842
3. Compston DAS. The 150th anniversary of the first depiction of the lesions of multiple sclerosis. J Neurol Neurosurg Psychiatry 1988; 51: 1249-52
4. Valentiner W. Ueber die Sclerose des Gehirns und RUckenmarks. Deutsche Klinik 1856; 8: 147-51
5. Frohmann C. Untersuchungen Uber die normale und pathologische anatomie des rilckenmarks. Zweiter theil. Jena, 1867:125
6. Charcot JM. Lectures on diseases of the nervous system. Translated by G. Sigerson. London: The New Sydenham Society, 1877: 158-222
7. Charcot JM. Histologic de le sclerose en plaques. Paris: Gazette des Hopitaux, 1868; 141: 554-5, 557-8
8. Rindfleisch E. Histologisches Detail zu der grauen Degeneration von Gehirn und Riickenmark. (Zugleich ein Beitrag zu der Lehre von der Entstehung und Verwandlung der Zelle.) Archiv fiir pathologische anatomie und Physiologie und fiir klinische Medicin 1863; 26: 474-83
9. Lassmann H. Comparative neuropathology of chronic experimental allergic encephalomyelitis and multiple sclerosis. Berlin: Springer-Verlag, 1983
10. Raine CS. Experimental allergic encephalomyelitis and experimental allergic neuritis. In: Koetsier JC, ed. Handbook of clinical neurology. Demyelinating Diseases. Vol. 47. Amsterdam: Elsevier Science Publishers, 1985:429-66
11. Young IR, Hall AS, Pallis CA, Legg NJ, Bydder GM, Steiner RE. Nuclear magnetic resonance imaging of the brain in multiple sclerosis. Lancet 1981;2: 1063-1066
12. Stewart WA, Hall LD, Berry K, Paty DW. Correlation between NMR scan and brain slice data in multiple sclerosis. Lancet 1984;2: 412
13. Ormerod IEC, Miller DH, McDonald WI, et al. The role of NMR imaging in the assessment of multiple sclerosis and isolated neurological lesions. A quantitative study. Brain 1987; 110: 1579-1616
14. Isaac C, Li DK, Genton M, et al. Multiple sclerosis: A serial study using MRI in relapsing patients. Neurology 1988;38:1511-15
15. Willoughby EW, Grochowski E, Li DKB, Oger J, Kastrukoff LF, Paty DW. Serial magnetic resonance scanning in multiple sclerosis: A second prospective study in relapsing patients. Ann Neurol 1989; 25: 43-9
16. Grossman RI, Gonzalez-Scarano F, Atlas SW, Galetta S, Silberberg DH. Multiple sclerosis: Gadolinium enhancement in MR imaging. Radiology 1986; 161: 721-5
17. Hawkins CP, MacKenzie F, Tofts P, du Boulay EPGH, McDonald WI. Patterns of blood-brain barrier breakdown in inflammatory de-myelination. Brain 1991; 114: 801-10
18. Katz D, Taubenberger JK, Cannella B, McFarlin DE, Raine CS, McFarland H. Correlation between MRI findings and lesion development in chronic active multiple sclerosis. Ann Neurol 1993; 34: 661-9
19. Barratt HJ, Miller D, Rudge P. The site of the lesion causing deafness in multiple sclerosis. Scand Audiol 1988; 17: 67-71
20. Kermode AG, Thompson AJ, Tofts P, et al. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis: Pathogenetic and clinical implications. Brain 1990; 113: 1477-89
21. Thompson AJ, Kermode AG, Wicks D, et al. Major differences in the dynamics of primary and secondary progressive multiple sclerosis. Ann Neurol 1991; 29: 53-62
22. Koopmans RA, Li DKB, Oger JJF, et al. Chronic progressive multiple sclerosis: Serial magnetic resonance brain imaging over six months. Ann Neurol 1989; 26: 248-56
23. Davie CA, Hawkins CP, Barker GJ, et al. Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions. Brain 1994 (in press)
24. Adams CWM, Poston RN, Buk SJ. Pathology, histochemistry and immunocytochemistry of lesions in acute multiple sclerosis. J Neurol Sci 1989; 92: 291-306
25. Youl BD, Turano G, Miller DH, et al. The pathophysiology of acute optic neuritis: An association of gadolinium leakage with clinical and electrophysiological deficits. Brain 1991; 114: 2437-50
26. Lightman S, McDonald WI, Bird AC, et al. Retinal venous sheathing in optic neuritis. Its significance for the pathogenesis of multiple sclerosis. Brain 1987; 110: 405-14
27. Graham EM, Francis DA, Sanders MD, Rudge P. Ocular inflammatory changes in established multiple sclerosis. J Neurol Neuro-surg Psychiatry 1989; 52: 1360-3
28. Barnes D, McDonald WI, Johnson G, Tofts PS, Landon DN. Quantitative nuclear magnetic resonance imaging: Characterisation of experimental cerebral oedema. J Neurol Neurosurg Psychiatry 1987; 50: 125-33
29. Larsson HBW, Frederiksen J, Kjaer L, Henriksen O, Olesen J. In vivo determination of T, and T2 in the brain of patients with severe but stable multiple sclerosis. Mag Res Med 1988; 7: 43-55
30. Barnes D, Munro PMG, Youl BD, Prineas JW, McDonald WI. The longstanding MS lesion. A quantitative MRI and electron microscopic study. Brain 1991; 114: 1271-80
31. McDonald WI. The effects of experimental demyelination on conduction in peripheral nerve: A histological and electrophysiological study. II. Electrophysiological observation. Brain 1963; 86: 501-24
32. McDonald WI, Sears TA. The effects of experimental demyelination on nerve conduction in the central nervous system. Brain 1970; 93: 583-98
33. Halliday AM, McDonald WI, Mushin J. Delayed visual evoked response in optic neuritis. Lancet 1972; 1: 982-985
34. Brosnan CF, Litwak MS, Schroeder CE, Selmaj K, Raine CS, Arez-zo JC. Preliminary studies of cytokine-induced functional effects on the visual pathways in the rabbit. J Neuroimmunol 1989; 25: 227-39
35. Brinkmeier H, Kaspar A, Wietholter H, Riidel R. Interleukin-2 inhibits sodium currents in human muscle cells. Pfliigers Arch 1992; 420: 621-3
36. Kagan BL, Baldwin RL, Munoz D, Wisnieski BJ. Formation of ion-permeable channels by tumor necrosis factor-a. Science 1992; 255: 1427-30
37. Bostock H, Sears TA. The internodal axon membrane: Electrical excitability and continuous conduction in segmental demyelination. J Physiol 1978; 280: 273-301
38. Smith KJ, Bostock H, Hall SM. Saltatory conduction precedes re-myelination in axons demyelinated with lysophosphatidyl choline. J Neurol Sci 1982; 54: 13-31
39. Black JA, Felts P, Smith KJ, Kocsis JD, Waxman SG. Distribution of sodium channels in chronically demyelinated spinal cord axons: Immuno-ultrastructural localization and electrophysiological observations. Brain Res 1991; 544: 59-70
40. England JD, Gamboni F, Levinson SR, Finger TE. Changed distribution of sodium channels along demyelinated axons. Proc Natl Acad Sci USA 1990; 87: 6777-80
41. Wisniewski HM, Oppenheimer D, McDonald WI. Relation between myelination and function in MS and EAE. (Abstract) J Neuropathol Exp Neurol 1976: 35: 327
42. Moll C, Mourre C, Lazdunsky M, Ulrich J. Increase of sodium channels in demyelinated lesions of multiple sclerosis. Brain Res 1991; 556: 311-16
43. Prineas JW, Barnard RO, Kwon EE, Sharer LR, Cho E-S. Multiple sclerosis: Remyelination of nascent lesions. Ann Neurol 1993; 33: 137-51
44. Kriss A, Francis DA, Cuendet F, et al. Recovery after optic neuritis in childhood. J Neurol Neurosurg Psychiatry 1988; 51: 1253-8
45. Prineas JW, Barnard RO, Revesz T, Kwon EE, Sharer L, Cho E-S. Multiple sclerosis. Pathology of recurrent lesions. Brain 1993; 116: 681-93
46. Kidd D, Thorpe JW, Thompson AJ, et al. Spinal cord MRI using multi-array coils and fast spin echo. II: Findings in multiple sclerosis. Neurology 1993; 43: 2632-7
47. Filippi M, Barker GJ, Horsfield MA, et al. Benign and secondary progressive multiple sclerosis: A preliminary quantitative MRI study. J Neurol 1994 (in press)
48. The IFN 3 Multiple Sclerosis Study Group. Interferon p-lb is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicentre, randomized, double-blind, placebo-controlled trial. Neurology 1993; 43: 655-661
49. Paty DW, Li DKB, The UBC MS/MRI Study Group, the IFN 3 Multiple Sclerosis Study Group. Interferon P-lb is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicentre, randomized, double-blind, placebo-controlled trial. Neurology 1993; 43: 662-7
50. Kidd D, Revesz TR, Thompson AJ, McDonald WI. A comparative clinicopathological study of progressive multiple sclerosis. (Abstract) Ann Neurol 1993; 34: 308