Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis

The Lancet

Volumn 343, Issue 8912, 1994, Pages 1536-1538

  Zoller B ^a   Dahlback B ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 5;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILY STUDY; FEMALE; GENETIC LINKAGE; HUMAN; MALE; POINT MUTATION; PRIORITY JOURNAL; THROMBOPHILIA;

EID: 0028291210     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(94)92940-8     Document Type: Article

References (10)

1. The protein C anticoagulant system
2. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C
3. Resistance to activated protein C as a basis for venous thrombosis
4. Anticoagulant protein C pathway defective in majority of thrombophilic patients
5. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden thrombophilia study
6. Resistance to activated protein C in nine thrombophilic families: interference in a protein S functional assay
7. Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V
8. A human vascular disorder, supravalvular aortic stenosis, maps to chromosome 7
9. The serine protease cofactor V is synthesized by lymphocytes
10. Localization of the gene encoding human factor V to chromosome 1q21-25