Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs

Journal of Pharmacology and Experimental Therapeutics

Volumn 270, Issue 1, 1994, Pages 250-259

  Underwood, D C ^a   Kotzer, C J ^a   Bochnowicz, S ^a   Osborn, R R ^a   Luttmann, M A ^a   Hay, D W P ^a   Torphy, T J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE; LEUKOTRIENE D4; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM; SIGUAZODAN; ZARDAVERINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY PLETHYSMOGRAPHY; BRONCHOSPASM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENTIATION; EOSINOPHILIA; INTRAGASTRIC DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; TRACHEA;

ANIMAL; ANTIGENS; BRONCHIAL SPASM; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOCONSTRICTION; COMPARATIVE STUDY; DRUG SYNERGISM; EOSINOPHILS; GUANIDINES; GUINEA PIGS; HISTAMINE ANTAGONISTS; IN VITRO; ISOENZYMES; LEUKOTRIENE D4; MALE; PHOSPHODIESTERASE INHIBITORS; PLETHYSMOGRAPHY, WHOLE BODY; PULMONARY EOSINOPHILIA; PYRIDAZINES; PYRROLIDINONES; ROLIPRAM; TRACHEA;

EID: 0028289793     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)