Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets

Neuron

Volumn 12, Issue 5, 1994, Pages 1161-1171

  McMahon, Stephen B ^a   Armanini, Mark P ^b   Ling, Lanway H ^b   Phillips, Heidi S ^b  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROGOLD; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIN 3; PROTEIN TYROSINE KINASE; RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLADDER INNERVATION; FEMALE; GASTROCNEMIUS MUSCLE; IN SITU HYBRIDIZATION; MALE; MUSCLE INNERVATION; NONHUMAN; PRIORITY JOURNAL; RAT; SAPHENOUS NERVE; SCIATIC NERVE; SENSORY NERVE CELL; SPINAL GANGLION;

AFFERENT PATHWAYS; AGING; ANIMAL; AXONAL TRANSPORT; FEMALE; GANGLIA, SPINAL; GENE EXPRESSION; IN SITU HYBRIDIZATION; MALE; NEURONS, AFFERENT; PROTEIN-TYROSINE KINASE; PROTO-ONCOGENE PROTEINS; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TRKA; RECEPTOR, TRKB; RECEPTOR, TRKC; RECEPTORS, GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; RNA, MESSENGER; SKIN;

EID: 0028289478     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(94)90323-9     Document Type: Article

References (53)

1. Neurotrophin-5: a novel neurotrophic factor that activates both trk and trkB
2. Keeping track of neurotrophin receptors
3. Neurotrophin receptors: a window into neuronal differentiation
4. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons
5. Transganglionic regulation of central terminals of dorsal root ganglion cells by nerve growth factor (NGF)
6. The cranial sensory ganglia in culture: differences in the response of place-derived and neural crest derived neurons to nerve growth factor
7. The response of chick sensory neurons to brain-derived neurotrophic factor
8. Neural crestderived proprioceptive neurons express nerve growth factor receptors, but are not supported by nerve growth factor in culture
9. NT-3 stimulates sympathetic neuroblast proliferation by promoting precursor survival
10. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
11. Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: evidence for a regulatory function of nerve growth factor in vivo
12. Neurotrophins and their receptors-current concepts and implications for neurologic disease
13. Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development
14. Biological importance of the retrograde transport of nerve growth factors in sensory neurons
15. Evolutionary studies of the nerve growth factor reveal a novel member abundantly expressed in Xenopus ovary
16. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low affinity NGF receptor
17. Neurotrophins promote motor neuron survival and are present in embryonic limb bud
18. Identification and characterization of a novel member of the nerve growth factor family
19. Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture
20. Patterns of termination of biochemically characterized sensory neurons
21. Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells
22. Nerve growth factor mediates signal transduction through Trk homodimer receptors
23. Tyrosine phosphorylation and tyrosine kinase activity of the trk protooncogene product induced by NGF
24. trkB, a novel tyrosine kinase receptor expresssed during mouse neural development
25. The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain
26. The trk proto-oncogene encodes a receptor for nerve growth factor
27. Targeted disruption of trkC, the neurotrophin-3 receptor gene, eliminates la muscle afferents and results in loss of proprioception
28. trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3
29. Nerve growth factor and nociception
30. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons
31. Placode and neural crest-derived sensory neurons are responsible at early developmental stages to brain-derived neurotrophic factor
32. The trk proto-oncogene rescues NGF responsiveness in mutant NGF-non responsive PC12 cell lines
33. Neurotrophin-3: a neurotrophic factor related to NGF and BDNF
34. Expression of the trk protooncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development
35. Plasticity of central terminations of primary sensory neurons in the adult animal
36. The nerve growth factor family of receptors
37. trkB, a neural receptor protein-tyrosine kinase: evidence for a fulllength and two truncated receptors
38. Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia
39. Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons
40. Epi-polarised illumination and emulsion autoradiographs
41. The receptors for nerve growth factor and other neurotrophins
42. Counting sectioned cells via mathematical reconstruction
43. Primary structure and biological activity of a novel human neurotrophic factor
44. Selective dependence of mammalian dorsal root ganglion neurons on nerve growth factor during embryonic development
45. Novel roles for neu rotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
46. Lectin and neuropeptide labeling of separate populations of dorsal root ganglion neurons and associated ‘nociceptor’ thin axons in rat testis and cornea whole-mount preparations
47. Severe sensory and sympathetic neuropathies in mice carrying a disrupted trk/NGF receptor gene
48. The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells
49. Alternate forms of TrkC with different functional capabilities
50. Histochemical characterization of sensory neurons with high-affinity receptors for nerve growth factor
51. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF