Arachidonic acid and diacylglycerol act synergistically through protein kinase C to persistently enhance synaptic transmission in the hippocampus

Neuroscience

Volumn 60, Issue 3, 1994, Pages 737-743

  Bramham, C R ^a   Alkon, D L ^a   Lester, D S ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ARACHIDONIC ACID; DIACYLGLYCEROL; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; STAUROSPORINE;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

ANIMAL; ARACHIDONIC ACID; DIGLYCERIDES; DRUG SYNERGISM; ENZYME ACTIVATION; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; NERVE TISSUE PROTEINS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; SECOND MESSENGER SYSTEMS; SYNAPTIC TRANSMISSION;

EID: 0028285856     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(94)90501-0     Document Type: Article

References (56)

1. Translocation of protein kinase C activity may mediate hippocampal long-term potentiation
2. + currents mediates retention of a learned association
3. + channels by cytoplasmic and membrane-associated C-kinase
4. 2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers
5. Arachidonic acid in the modulation of excitable membrane function and at the onset of brain damage
6. Lipid activation of protein kinase C
7. A synaptic model of memory: long-term potentiation in the hippocampus
8. PKC and cellular transformation
9. Opioid receptor dependent long-term potentiation: peptidergic regulation of synaptic plasticity in the hippocampus
10. Synaptic plasticity in the hippocampus is modulated by behavioral state
11. The role of arachidonic acid and oxygen radical metabolites in the pathogenesis of vasogenic brain edema and astrocytic swelling
12. Synergistic activation of type III protein kinase C by cis-fatty acid and diacylglycerol
13. Increase in arachidonic acid concentration in a post-synaptic membrane fraction following the induction of long-term potentiation in the dentate gyrus
14. Arachidonic acid and diglyceride facilitate evoked glutamate release
15. Long-term changes of synaptic transmission induced by arachidonic acid in the CA1 subfield of the rat hippocampus
16. NMDA receptors activate the arachidonic acid cascade system in striatal neurons
17. Lipid vesicles which can bind to protein kinase C and activate the enzyme in the presence of EGTA
18. Presynaptic facilitation of glutamate release from isolated hippocampal mossy fiber nerve endings by arachidonic acid
19. Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation
20. Postsynaptic then presynaptic protein kinase C activity may be necessary for long-term potentiation
21. Phosphorylation of the presynaptic protein B-50 (GAP-43) is increased during electrically induced long-term potentiation
22. Both arachidonic acid and l-oleolyl-2-acetyl glycerol in low magnesium solution induce long-term potentiation in hippocampal CA1 neurons in vitro
23. Arachidonic acid modulates hippocampal calcium current via protein kinase C and oxygen radicals
24. Mechanism of protein kinase C activation during the induction and maintenance of long-term potentiation probed using a selective peptide substrate
25. Persistent protein kinase activation in the maintenance phase of long-term potentiation
26. What role for long-term potentiation in learning and the maintenance of memories?
27. Demonstration of presynaptic protein kinase C activation following long-term potentiation in rat hippocampal slices
28. In vitro linoleic acid activation of protein kinase C
29. Activation of protein kinase C phosphorylation pathways: a role for storage of associative memory
30. Membrane-associated protein kinase C
31. Persistent, membrane-associated protein kinase C: from model membranes to synaptic long-term potentiation
32. Arachidonic acid and diacylglycerol act synergistically to activate protein kinase C in vitro and in vivo
33. A newly discovered protein kinase C activator (oleic acid) enhances long-term potentiation in the intact hippocampal slice
34. The role of protein kinase C in long-term potentiation: a testable model
35. 2
36. Is arachidonic acid a retrograde messenger in long-term potentiation?
37. Nordihydroguaiaretic acid blocks the synaptic component of long-term potentiation and the associated increases in release of glutamate and arachidonate: an in vivo study in the dentate gyrus of the rat
38. Potentiation of synaptic transmission in the hippocampus by phorbol esters
39. Inhibition of postsynaptic PKC or CAMII blocks induction but not expression of LTP
40. 2 inhibitor, on the induction and maintenance of LTP in hippocampal slices
41. Potentiation of NMDA receptor current by arachidonic acid
42. Direct stimulation of purified protein kinase C by unsaturated fatty acids (oleate, arachidonate) in the absence of phospholipids and calcium
43. Activation and regulation of protein kinase C enzymes
44. Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger
45. Differential effects of phospholipase inhibitors in longterm potentiation in the rat hippocampal mossy fiber synapses and Schaffer commissural synapses
46. Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling
47. A quantitative method for measuring in vivo fatty-acid incorporation into and turnover within brain phospholipids: review and critical analysis
48. Persistent activation of the ζ isoform of protein kinase C in the maintenance of long-term potentiation
49. Exposure to N-methyl-d-aspartate increases release of arachidonic acid in primary cultures of rat hippocampal neurons and not in astrocytes
50. Arachidonic acid cascade and signal transduction
51. Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: its possible implications
52. Arachidonic acid metabolism in seizures
53. Associative learning potentiates protein kinase C activation in synaptosomes of the rabbit hippocampus
54. Transduction of a protein kinase C-generated signal into the long-lasting facilitation of glutamate release
55. Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus
56. Synergistic potentiation of glutamate release by arachidonic acid and oleoyl-acetyl-glycerol