Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells

Diabetes

Volumn 43, Issue 7, 1994, Pages 947-953

  Otonkoski, Timo ^a   Beattie, Gillian M ^a   Rubin, Jeffrey S ^b   Lopez, Ana D ^a   Baird, Andrew ^a   Hayek, Alberto ^a  

^a Whittier Institute for Diabetes   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; FIBROBLAST GROWTH FACTOR; INSULIN; KERATINOCYTE GROWTH FACTOR; SCATTER FACTOR; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; FETUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INSULIN LIKE ACTIVITY; MITOGENESIS; MORPHOGENESIS; ORGANOGENESIS; PANCREAS; PANCREAS ISLET CELL; PRIORITY JOURNAL;

EID: 0028284507     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.43.7.947     Document Type: Article

References (25)

1. Gumbiner BM: Epithelial morphogenesis. Cell 69:385-387, 1992
2. Pictet R, Rutter WJ: Development of the embryonic endocrine pancreas. In Handbook of Physiology; Section 7: Endocrinology. Vol. I. Steiner D, Freinkel N, Eds. Baltimore, MD, Williams and Wilkins, 1972, p. 25-66
3. Gu D, Sarvetnick N: Epithelial cell proliferation and islet neogenesis in IFN-γ transgenic mice. Development 118:33-40, 1993
4. Dudek RW, Lawrence IE Jr, Hill RS, Johnson RC: Induction of islet cytodifferentiation by fetal mesenchyme in adult pancreatic ductal epithelium. Diabetes 40:1041-1048, 1991
5. Derynck R: The physiology of transforming growth factor-α. Adv Cancer Res 58:27-52, 1992
6. G. Heine UI, Munoz EF, Flanders KC, Ellingsworth LR, Lam H-YP, Thompson NL, Roberts AB, Sporn MB: Role of transforming growth factor-β in the development of the mouse embryo. J Cell Biol 105:2861-2876, 1987
7. Gospodarowicz D: Biological activities of fibroblast growth factors. In The Fibroblast Growth Factor Family. Baird A, Klagsbrun M, Eds. New York, New York Academy of Sciences, 1991, p. 1-8
8. Strain AJ: Hepatocyte growth factor, another ubiquitous cytokine. J Endocrinol 137:1-5, 1993
9. Rizzino A: Transforming growth factor-β: multiple effects on cell differentiation and extracellular matrices. Dev Biol 130:411-422, 1988
10. Baird A, Böhlen P: Fibroblast growth factors. In Handbook of Experimental Pharmacology; Vol. 95/I: Peptide Growth Factors and Their Receptors I. Sporn MB, Roberts AB, Eds. Berlin, Springer-Verlag, 1990, p. 369-418
11. Masumoto A, Yamamoto N: Sequestration of a hepatocyte growth factor in extracellular matrix in normal adult rat liver. Biochem Biophys Res Commun 174:90-95, 1991
12. Hellerström C, Swenne I: Functional maturation and proliferation of fetal pancreatic β-cells. Diabetes 40 (Suppl. 2):89-93, 1991
13. Swenne I: Pancreatic beta-cell growth and diabetes mellitus. Diabetologia 35:193-201, 1992
14. Sandler S, Andersson A, Schnell A, Mellgren A, Tollemar J, Borg H, Petersson B, Groth C-G, Hellerstrom C: Tissue culture of human fetal pancreas: development and function of β-cells in vitro and transplantation of explants to nude mice. Diabetes 34:1113-1119, 1985
15. Otonkoski T, Beattie GM, Mally MI, Ricordi C, Hayek A: Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells. J Clin Invest 92:1459-1466, 1993
16. Beattie GM, Otonkoski T, Lopez AD, Hayek A: Maturation and function of human fetal pancreatic cells after cryopreservation. Transplantation 56:1340-1343, 1993
17. Otonkoski T, Knip M, Panula P, Andersson S, Wong I, Goldman H, Simell O: Morphology, yield and functional integrity of islet-like cell clusters in tissue culture of human fetal pancreata obtained after different means of abortion. Acta Endocrinol 118:68-76, 1988
18. Hinegardner RT: An improved fluorometric assay for DNA. Anal Biochem 39:197-201, 1971
19. Isacchi A, Statuto M, Chiesa R, Bergonzoni L, Rusnati M, Sarmientos P, Ragnotti G, Presta M: A six-amino acid deletion in basic fibroblast growth factor dissociates its mitogenic activity from its plasminogen activator-inducing capacity. Proc Natl Acad Sci USA 88:2628-2632, 1991
20. Ron D, Bottaro DP, Finch PW, Morris D, Rubin JS, Aaronson SA: Expression of biologically active recombinant keratinocyte growth factor structure/function analysis of amino-terminal truncation mutants. J Biol Chem 268:2984-2988, 1993
21. Erber WN, Mason DY: Immunoalkaline phosphatase labeling of terminal transferase in hematologic samples. Am J Clin Pathol 88:43-50, 1987
22. Sternberger LA, Hardy PH, Cuculis JJ, Meyer HG: The unlabeled antibody method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antiperoxidase) and its use in identification of spirochetes. J Histochem Cytochem 18:315-333, 1970
23. Furlong RA: The biology of hepatocyte growth factor/scatter factor. Bioessays 14:613-617, 1992
24. Weidner KM, Arakaki N, Hartmann G, Van de Kerchove J, Weingart S, Rieder H, Fonatsch C, Tsubouchi H, Hishida T, Daikuhara Y, Birchmeier W: Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci USA 88:7001-7005, 1991
25. Montesano R, Matsumoto K, Nakamura T, Orci L: Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67:901-908, 1991