Relative importance of DT-diaphorase and hypoxia in the bioactivation of e09 by human lung tumor cell lines

International Journal of Radiation Oncology, Biology, Physics

Volumn 29, Issue 2, 1994, Pages 295-299

  Plumb, Jane A ^a   Gerritsen, Martijn ^a   Milroy, R ^b   Thomson, Patricia ^a   Workman, Paul ^a  

^a CRC Department of Medical Oncology University of Glasgow Alexander Stone Building Garscube Estate Bearsden Glasgow G61 1BD UK ^*

^b STOBHILL HOSPITAL   (United Kingdom)

Author keywords

bioreductive agents; DT diaphorase; E09; Hypoxic sensitization

Indexed keywords

5 (1 AZIRIDINYL) 3 HYDROXYMETHYL 2 (3 HYDROXY 1 PROPENYL) 1 METHYL 4,7 INDOLEDIONE; CARMUSTINE; CISPLATIN; CYTOCHROME B5 REDUCTASE; CYTOCHROME P450; MITOMYCIN C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TIRAPAZAMINE;

CANCER CELL CULTURE; CLONOGENIC ASSAY; CONFERENCE PAPER; CROSS RESISTANCE; CYTOTOXICITY; DRUG ACTIVATION; DRUG RESISTANCE; DRUG SENSITIVITY; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOXIA; LUNG CANCER; METABOLIC ACTIVATION; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

ANOXIA; ANTINEOPLASTIC AGENTS; AZIRIDINES; BIOTRANSFORMATION; HUMAN; INDOLES; LUNG NEOPLASMS; NAD(P)H DEHYDROGENASE (QUINONE); OXIDATION-REDUCTION; TUMOR CELLS, CULTURED;

EID: 0028282993     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(94)90278-X     Document Type: Article

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