In vitro inhibition, by loratadine and descarboxyethoxyloratadine, of histamine release from human basophils, and of histamine release and intracellular calcium fluxes in rat basophilic leukemia cells (RBL-2H3)

Biochemical Pharmacology

Volumn 47, Issue 5, 1994, Pages 789-794

  Berthon, Brigitte ^a   Taudou, Georges ^b   Combettes, Laurent ^a   Czarlewski, Wienia ^c   Carmi Leroy, Annick ^b   Marchand, Françoise ^b   Weyer, Anna ^b  

^a INSERM   (France)

^b INSTITUT PASTEUR   (France)

^c Laboratoires Schering Plough   (France)

Author keywords

Ca2+ fluxes; H1 antihistamine; histamine release; human basophils; loratadine; RBL cells

Indexed keywords

ANTIHISTAMINIC AGENT; DESLORATADINE; DRUG METABOLITE; LORATADINE; LORATADINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BASOPHIL; CALCIUM TRANSPORT; CONTROLLED STUDY; HISTAMINE RELEASE; HUMAN; HUMAN CELL; LEUKEMIA CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; ANTIBODIES, ANTI-IDIOTYPIC; BASOPHILS; CALCIUM; CYTOSOL; DINITROBENZENES; DINITROPHENOLS; HISTAMINE RELEASE; HUMAN; IMMUNOGLOBULIN G; IN VITRO; LEUKEMIA, BASOPHILIC, ACUTE; LORATADINE; RATS; SERUM ALBUMIN, BOVINE; TUMOR CELLS, CULTURED;

EID: 0028281973     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(94)90478-2     Document Type: Article

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