Crystal Structure of the Mutant Yeast Triosephosphate Isomerase in Which the Catalytic Base Glutamic Acid 165 Is Changed to Aspartic Acid

Biochemistry

Volumn 33, Issue 10, 1994, Pages 2824-2829

  Joseph McCarthy, Diane ^a   Rost, Linda E ^b   Komives, Elizabeth A ^c,d   Petsko, Gregory A ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BRANDEIS UNIVERSITY   (United States)

^c HARVARD UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GLUTAMIC ACID; HYDROXAMIC ACID DERIVATIVE; MUTANT PROTEIN; TRIOSEPHOSPHATE ISOMERASE;

AMINO ACID SUBSTITUTION; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MUTATION; NONHUMAN; PRIORITY JOURNAL; X RAY DIFFRACTION; YEAST;

AMINO ACID SEQUENCE; ASPARTIC ACID; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; GLUTAMATES; GLUTAMIC ACID; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SUPPORT, U.S. GOV'T, P.H.S.; TRIOSE-PHOSPHATE ISOMERASE; X-RAY DIFFRACTION;

EID: 0028279839     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00176a011     Document Type: Article

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