-
1
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990, 61:759-767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
2
-
-
0023256456
-
Presence of ras gene mutations in human colorectal cancers
-
Bos JL, Fearon ER, Hamilton SR, Verlaan-de Vries M, van Boom JH, van der Eb AJ, Vogelstein B: Presence of ras gene mutations in human colorectal cancers. Nature 1987, 327:293-297
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
Verlaan-de Vries, M.4
Van Boom, J.H.5
Van Der Eb, A.J.6
Vogelstein, B.7
-
4
-
-
0023105328
-
Protooncogene abnormalities in colon cancers and adenomatous polyps
-
Meltzer SJ, Ahnen DJ, Battifora H, Yokota J, Cline MJ: Protooncogene abnormalities in colon cancers and adenomatous polyps. Gastroenterology 1987, 92: 1174-1180
-
(1987)
Gastroenterology
, vol.92
, pp. 1174-1180
-
-
Meltzer, S.J.1
Ahnen, D.J.2
Battifora, H.3
Yokota, J.4
Cline, M.J.5
-
6
-
-
0024536654
-
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
-
Baker SJ, Fearon ER, Nigro JM, Hamilton SR, Preisinger AC, Jessup JM, van Tuinen P, Ledbetter DH, Baker DF, Nakamura Y, White R, Vogelstein B: Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 1989, 244:217-221
-
(1989)
Science
, vol.244
, pp. 217-221
-
-
Baker, S.J.1
Fearon, E.R.2
Nigro, J.M.3
Hamilton, S.R.4
Preisinger, A.C.5
Jessup, J.M.6
Van Tuinen, P.7
Ledbetter, D.H.8
Baker, D.F.9
Nakamura, Y.10
White, R.11
Vogelstein, B.12
-
7
-
-
0025056930
-
Identification of a chromosome 18q gene that is altered in colorectal cancers
-
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, Hamilton SR, Preisinger AC, Thomas G, Kinzler KW, Vogelstein B: Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 1990, 247:49-56
-
(1990)
Science
, vol.247
, pp. 49-56
-
-
Fearon, E.R.1
Cho, K.R.2
Nigro, J.M.3
Kern, S.E.4
Simons, J.W.5
Ruppert, J.M.6
Hamilton, S.R.7
Preisinger, A.C.8
Thomas, G.9
Kinzler, K.W.10
Vogelstein, B.11
-
8
-
-
0025909734
-
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers
-
Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hamilton SR, Hedge P, Markham A, Carlson M, Joslyn G, Groden J, White R, Miki Y, Miyoshi Y, Nishisho I, Nakamura Y: Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science 1991, 251: 1366-1370
-
(1991)
Science
, vol.251
, pp. 1366-1370
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Vogelstein, B.3
Bryan, T.M.4
Levy, D.B.5
Smith, K.J.6
Preisinger, A.C.7
Hamilton, S.R.8
Hedge, P.9
Markham, A.10
Carlson, M.11
Joslyn, G.12
Groden, J.13
White, R.14
Miki, Y.15
Miyoshi, Y.16
Nishisho, I.17
Nakamura, Y.18
-
9
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B, Kinzler KW: APC mutations occur early during colorectal tumorigenesis. Nature 1992, 359:235-237
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
10
-
-
0026439207
-
Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction
-
Peinado MA, Malkhosyan S, Velazquez A, Perucho M: Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction. Proc Natl Acad Sci USA 1992, 89:10065-10069
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10065-10069
-
-
Peinado, M.A.1
Malkhosyan, S.2
Velazquez, A.3
Perucho, M.4
-
11
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen LA, Peltomäki P, Leach FS, Sistonen P, Pylkkänen L, Mecklin J-P, Järvinen H, Powell SM, Jen J, Hamilton SR, Petersen GM, Kinzler KW, Vogelstein B, de la Chapelle A: Clues to the pathogenesis of familial colorectal cancer. Science 1993, 260:812-816
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomäki, P.2
Leach, F.S.3
Sistonen, P.4
Pylkkänen, L.5
Mecklin, J.-P.6
Järvinen, H.7
Powell, S.M.8
Jen, J.9
Hamilton, S.R.10
Petersen, G.M.11
Kinzler, K.W.12
Vogelstein, B.13
De La Chapelle, A.14
-
12
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau SN, Bren G, Schaid D: Microsatellite instability in cancer of the proximal colon. Science 1993, 260:816-819
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
13
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993, 363:558-561
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
14
-
-
0027136828
-
Genomic instability in colorectal cancer: Relationship of clinicopathological variables and family history
-
Lothe RA, Peltomäki P, Meling GI, Aaltonen LA, Nystrom-Lahti M, Pylkkänen L, Heimdal K, Andersen TI, Moller P, Rognum TO, Fossa SD, Haldorsen T, Langmark F, Brogger A, de la Chapelle A, Borresen A-L: Genomic instability in colorectal cancer: relationship of clinicopathological variables and family history. Cancer Res 1993, 53:5849-5852
-
(1993)
Cancer Res
, vol.53
, pp. 5849-5852
-
-
Lothe, R.A.1
Peltomäki, P.2
Meling, G.I.3
Aaltonen, L.A.4
Nystrom-Lahti, M.5
Pylkkänen, L.6
Heimdal, K.7
Andersen, T.I.8
Moller, P.9
Rognum, T.O.10
Fossa, S.D.11
Haldorsen, T.12
Langmark, F.13
Brogger, A.14
De La Chapelle, A.15
Borresen, A.-L.16
-
15
-
-
0027306173
-
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair
-
Strand M, Prolla TA, Liskay RM, Petes TD: Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 1993, 365:274-276
-
(1993)
Nature
, vol.365
, pp. 274-276
-
-
Strand, M.1
Prolla, T.A.2
Liskay, R.M.3
Petes, T.D.4
-
16
-
-
0027205395
-
Slippery DNA and diseases
-
Kunkel TA: Slippery DNA and diseases. Nature 1993, 365:207-208
-
(1993)
Nature
, vol.365
, pp. 207-208
-
-
Kunkel, T.A.1
-
17
-
-
0027248156
-
Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review
-
Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, Cavalieri J, Boland CR: Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 1993, 104:1535-1549
-
(1993)
Gastroenterology
, vol.104
, pp. 1535-1549
-
-
Lynch, H.T.1
Smyrk, T.C.2
Watson, P.3
Lanspa, S.J.4
Lynch, J.F.5
Lynch, P.M.6
Cavalieri, J.7
Boland, C.R.8
-
18
-
-
0027263363
-
Genetic mapping of a locus predisposing to human colorectal cancer
-
Peltomäki P, Aaltonen LA, Sistonen P, Pylkkanen L, Mecklin J-P, Järvinen H, Green JS, Jass JR, Weber JL, Leach FS, Petersen JM, Hamilton SR, de la Chapelle A, Vogelstein B: Genetic mapping of a locus predisposing to human colorectal cancer. Science 1993, 269:810-812
-
(1993)
Science
, vol.269
, pp. 810-812
-
-
Peltomäki, P.1
Aaltonen, L.A.2
Sistonen, P.3
Pylkkanen, L.4
Mecklin, J.-P.5
Järvinen, H.6
Green, J.S.7
Jass, J.R.8
Weber, J.L.9
Leach, F.S.10
Petersen, J.M.11
Hamilton, S.R.12
De La Chapelle, A.13
Vogelstein, B.14
-
19
-
-
0027485551
-
Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer
-
Lindblom A, Tammergård P, Werelius B, Nordenskjöld M: Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer. Nature Genet 1993, 5:279-282
-
(1993)
Nature Genet
, vol.5
, pp. 279-282
-
-
Lindblom, A.1
Tammergård, P.2
Werelius, B.3
Nordenskjöld, M.4
-
20
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R, Lescoe MK, Rao MRS, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R: The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993, 75: 1027-1038
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.S.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
21
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, Peltomäki P, Sistonen P, Aaltonen LA, Nystran-Lahti M, Guan X-Y, Zhang J, Meltzer PS, Yu J-W, Kao F-T, Chen DJ, Cerosaletti KM, Fournier REK, Todd S, Lewis T, Leach RJ, Naylor SL, Weissenbach J, Mecklin J-P, Järvinen H, Petersen GM, Hamilton SR, Green J, Jass J, Watson P, Lynch HT, Trent JM, de la Chapelle A, Kinzler KW, Vogelstein B: Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993, 75:1215-1225
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
Liu, B.4
Jen, J.5
Parsons, R.6
Peltomäki, P.7
Sistonen, P.8
Aaltonen, L.A.9
Nystran-Lahti, M.10
Guan, X.-Y.11
Zhang, J.12
Meltzer, P.S.13
Yu, J.-W.14
Kao, F.-T.15
Chen, D.J.16
Cerosaletti, K.M.17
Fournier, R.E.K.18
Todd, S.19
Lewis, T.20
Leach, R.J.21
Naylor, S.L.22
Weissenbach, J.23
Mecklin, J.-P.24
Järvinen, H.25
Petersen, G.M.26
Hamilton, S.R.27
Green, J.28
Jass, J.29
Watson, P.30
Lynch, H.T.31
Trent, J.M.32
De La Chapelle, A.33
Kinzler, K.W.34
Vogelstein, B.35
more..
-
22
-
-
0027137935
-
+ tumor cells
-
+ tumor cells. Cell 1993, 75:1227-1236
-
(1993)
Cell
, vol.75
, pp. 1227-1236
-
-
Parsons, R.1
Li, G.-M.2
Longley, M.J.3
Fang, W.-H.4
Papadopoulos, N.5
Jen, J.6
De La Chapelle, A.7
Kinzler, K.W.8
Vogelstein, B.9
Modrich, P.10
-
23
-
-
0025779536
-
Hereditary non-polyposis colorectal cancer
-
Vasen HFA, Mecklin JP, Kahn PM, Lynch HT: Hereditary non-polyposis colorectal cancer. Lancet 1991, 338:877
-
(1991)
Lancet
, vol.338
, pp. 877
-
-
Vasen, H.F.A.1
Mecklin, J.P.2
Kahn, P.M.3
Lynch, H.T.4
-
24
-
-
84901963379
-
Allelic status of chromosome 18q and prognosis of colorectal cancer
-
in press
-
Jen J, Kim H, Piantadosi S, Liu Z-F, Levitt RC, Sistonen P, Kinzler KW, Vogelstein B, Hamilton SR: Allelic status of chromosome 18q and prognosis of colorectal cancer. N Engl J Med (in press)
-
N Engl J Med
-
-
Jen, J.1
Kim, H.2
Piantadosi, S.3
Liu, Z.-F.4
Levitt, R.C.5
Sistonen, P.6
Kinzler, K.W.7
Vogelstein, B.8
Hamilton, S.R.9
-
25
-
-
0023873577
-
A multivariate analysis of pathologic prognostic indicators in large bowel cancer
-
Wiggers T, Arends JW, Schutte B, Volovics L, Bosman FT: A multivariate analysis of pathologic prognostic indicators in large bowel cancer. Cancer 1988, 61:386-395
-
(1988)
Cancer
, vol.61
, pp. 386-395
-
-
Wiggers, T.1
Arends, J.W.2
Schutte, B.3
Volovics, L.4
Bosman, F.T.5
-
26
-
-
0023213901
-
A new prognostic classification of rectal cancer
-
Jass JR, Love SV, Northover JMA: A new prognostic classification of rectal cancer. Lancet 1987, 1:1303-1306
-
(1987)
Lancet
, vol.1
, pp. 1303-1306
-
-
Jass, J.R.1
Love, S.V.2
Northover, J.M.A.3
-
27
-
-
0025424347
-
Crohn's-like lymphoid reaction and colorectal carcinoma: A potential histologic prognosticator
-
Graham DM, Appelman HD: Crohn's-like lymphoid reaction and colorectal carcinoma: a potential histologic prognosticator. Modern Pathol 1990, 3:332-335
-
(1990)
Modern Pathol
, vol.3
, pp. 332-335
-
-
Graham, D.M.1
Appelman, H.D.2
-
28
-
-
0025152051
-
p53 mutations in colorectal cancer
-
Rodrigues NR, Rowan A, Smith MEF, Kern ZB, Bodmer WF, Gannon JV: p53 mutations in colorectal cancer. Proc Natl Acad Sci USA 1990, 87:7555-7559
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7555-7559
-
-
Rodrigues, N.R.1
Rowan, A.2
Smith, M.E.F.3
Kern, Z.B.4
Bodmer, W.F.5
Gannon, J.V.6
-
29
-
-
0023959795
-
Activating mutations for transformation by p53 produce a gene product that forms an hsc700-p53 complex with an altered half-life
-
Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ: Activating mutations for transformation by p53 produce a gene product that forms an hsc700-p53 complex with an altered half-life. Mol Cell Biol 1988, 8:531-539
-
(1988)
Mol Cell Biol
, vol.8
, pp. 531-539
-
-
Finlay, C.A.1
Hinds, P.W.2
Tan, T.H.3
Eliyahu, D.4
Oren, M.5
Levine, A.J.6
-
30
-
-
0027394094
-
Detection of p53 overexpression in routinely paraffin embedded tissue of human carcinoma, using a novel target unmasking fluid (TUF)
-
van den Berg FM, Bass IO, Polak MM, Offerhaus GJA: Detection of p53 overexpression in routinely paraffin embedded tissue of human carcinoma, using a novel target unmasking fluid (TUF). Am J Pathol 1993, 142: 381-385
-
(1993)
Am J Pathol
, vol.142
, pp. 381-385
-
-
Van Den Berg, F.M.1
Bass, I.O.2
Polak, M.M.3
Offerhaus, G.J.A.4
-
31
-
-
0028207349
-
An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
-
Bass IO, Mulder J-W, Offerhaus GJA, Vogelstein B, Hamilton SR: An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994, 172: 5-12
-
(1994)
J Pathol
, vol.172
, pp. 5-12
-
-
Bass, I.O.1
Mulder, J.-W.2
Offerhaus, G.J.A.3
Vogelstein, B.4
Hamilton, S.R.5
-
33
-
-
0025048761
-
Colorectal cancer: Evidence for distinct genetic categories based on proximal or distal tumor location
-
Bufill JA: Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location. Ann Intern Med 1990, 113:779-788
-
(1990)
Ann Intern Med
, vol.113
, pp. 779-788
-
-
Bufill, J.A.1
-
34
-
-
0022978562
-
Histopathology of colorectal carcinomas and adenomas in Cancer Family Syndrome
-
Mecklin JP, Sipponen P, Järvinen HJ: Histopathology of colorectal carcinomas and adenomas in Cancer Family Syndrome. Dis Colon Rectum 1986, 29:849-853
-
(1986)
Dis Colon Rectum
, vol.29
, pp. 849-853
-
-
Mecklin, J.P.1
Sipponen, P.2
Järvinen, H.J.3
-
35
-
-
0003035233
-
Histologic features of hereditary nonpolyposis colorectal carcinoma
-
Edited by J Utsunomiya and HT Lynch. Tokyo, Springer-Verlag
-
Smyrk TC, Lynch HT, Watson PA, Appelman HD: Histologic features of hereditary nonpolyposis colorectal carcinoma. Hereditary Colorectal Cancer. Edited by J Utsunomiya and HT Lynch. Tokyo, Springer-Verlag, 1990, pp 357-362
-
(1990)
Hereditary Colorectal Cancer
, pp. 357-362
-
-
Smyrk, T.C.1
Lynch, H.T.2
Watson, P.A.3
Appelman, H.D.4
-
36
-
-
0026669469
-
p53 function and dysfunction
-
Vogelstein B, Kinzler KW: p53 function and dysfunction. Cell 1992, 70:523-526
-
(1992)
Cell
, vol.70
, pp. 523-526
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
37
-
-
0026561245
-
The p53 tumor-suppressor gene
-
Levine AJ: The p53 tumor-suppressor gene. N Engl J Med 1992, 326:1350-1351
-
(1992)
N Engl J Med
, vol.326
, pp. 1350-1351
-
-
Levine, A.J.1
-
38
-
-
0026705327
-
p53: The ultimate tumor suppressor gene
-
Oren M: p53: the ultimate tumor suppressor gene. FASEB J 1992, 6:3169-3176
-
(1992)
FASEB J
, vol.6
, pp. 3169-3176
-
-
Oren, M.1
|