Eicosanoids, erections and erectile dysfunction

Prostaglandins, Leukotrienes and Essential Fatty Acids

Volumn 51, Issue 1, 1994, Pages 1-9

  Miller, M A W ^a   Morgan, R J ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; LINSIDOMINE; NITRIC OXIDE; PAPAVERINE; PHENTOLAMINE; PRIMROSE OIL; PROSTACYCLIN; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E1; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; THROMBOXANE A2 DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; DIABETIC NEUROPATHY; HUMAN; MALE; MALE SEXUAL DYSFUNCTION; MONKEY; NEUROTRANSMISSION; NONHUMAN; PAIN; PENIS ERECTION; PRIORITY JOURNAL; RAT; REVIEW;

ANIMAL; DIABETIC NEUROPATHIES; EICOSANOIDS; FATTY ACIDS, ESSENTIAL; HUMAN; IMPOTENCE; MALE; NITRIC OXIDE; NUCLEOTIDES, CYCLIC; PENILE ERECTION; PENIS; PROSTAGLANDINS;

ANIMALIA; PRIMULA;

EID: 0028272267     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/0952-3278(94)90171-6     Document Type: Review

References (104)

1. NIH Consensus Conference. Impotence
2. Human penile erection and organic impotence: normal histology and histopathology
3. Ultrastructural analysis of human penile corpus cavermosum: its significance in tumescence and detumescence
4. Gap junctions between human corpus cavernosum smooth muscle cells: identity of the connexin type and unitary conductance events
5. Intercellular communication through gap junctions a potential role in pharmacomechanical coupling and syncytial tissue contraction in vascular smooth muscle isolated from the human corpus cavernosum
6. Gap junctions between human corpus cavernosum smooth muscle cells in primary culture: electrophysiological and biochemical characteristics
7. Mechanism of human penile erection: an overview
8. Haemodynamics of penile erection
9. Mechanisms for contraction and relaxation of human penile smooth muscle
10. Mechanisms for the regulation of penile smooth muscle contractility
11. Local control of penile erection. Nerves, smooth muscle and endothelium
12. Blood flow measurement by the clearance methods in the human corpus cavemosum in the flaccid and erect states
13. Physiology of erection and pharmacological management of impotence
14. Impotence
15. Smooth muscle of the corpora cavernosae: role in penile erection
16. Mechanism of venous occlusion during canine penile erection: an anatomic demonstration
17. Haemodynamics of erection in the monkey
18. Haemodynamics of canine corpora cavernosa during erection
19. Further evidence of venous outflow obstruction during erection
20. Penile venous drainage in erectile dysfunction. Anatomical, radiological and functional considerations
21. Physiology of male sexual function
22. Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic noncholinergic neurotransmission
23. A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle
24. Ability of the human corpora cavernosa muscle to generate prostaglandins and thromboxanes in vitro
25. Prostacyclin synthesis by the corpora cavernosa of the human penis: evidence for muscarinic control and pathological implications
26. Prostaglandin 15-hydroxydehydroganase activity in human penile corpora cavernosa and its significance in prostaglandin-mediated erection
27. Comparative study of some isolated mammalian smooth muscle effectors of penile erection
28. Contraction and relaxation induced by some prostanoids in isolated human penile erectile tissue and cavernous artery
29. Characterization of contraction-mediating prostanoid receptors in human penile erectile tissues
30. Effect of the thromboxane receptor antagonist AH 23848 on human isolated corpus cavernosum
31. Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP activation
32. 2-adrenoceptors
33. Human corpora cavernosa smooth muscle cells in culture: influence of catecholamines and prostaglandins on cAMP formation [Abstract]
34. Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in α-adrenoceptor responsiveness with age and disease in isolated tissues
35. Endothelium-derived nitric oxide and cyclooxygenase products modulate corpus cavernosum smooth muscle tone
36. 2 in pig-tailed monkeys
37. Intracavernous pressure as an experimental index in a rat model for the evaluation of penile erection
38. Eicosanoids, impotence and pharmacologically induced erection
39. Nitric oxide: a physiological mediator of penile erection
40. A possible neural source of nitric oxide in the rat penis
41. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle
42. Cholinergic neurotransmission in human corpus cavernosum I Responses of isolated tissue
43. Actions of endothelin on isolated corpus cavernosum from rabbit and man
44. Functional effects, binding sites and immunolocalization of endothelin-1 in isolated penile tissues from man and rabbit
45. Gap junctions formed of connexin-43 are found between smooth muscle cells of human corpus cavernosum
46. Is impotence an arterial disorder? A study of arterial risk factors in 440 impotent men
47. Cigarette smoking and other vascular risk factors in vasculogenic impotence
48. The effect of cigarette smoke and diabetes mellitus on muscarinic stimulation of prostacyclin synthesis by the rat penis
49. Experimental diabetes mellitus inhibits prostacyclin synthesis by the rat penis: pathological implications
50. The prevalence of diabetic impotence
51. The effect of longterm intensified insulin treatment on the development of microvascular complications of diabetes mellitus
52. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
53. 1 receptors in cavernous tissue of men, monkeys and dogs
54. Smoking and erectile impotence
55. Nocturnal penile tumescence in cigarette smokers with erectile dysfunction
56. Oxygen tension regulates the nitric oxide pathway
57. Anoxia and corporal smooth muscle dysfunction a model for ischemic priaprism
58. Experimental hypercholesterolemia in rabbits induces cavernosal atherosclerosis with endothelial and smooth muscle cell dysfunction
59. Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent relaxation in hypercholesterolaemic patients
60. New concepts about the pathogenesis of atherosclerosis in diabetes mellitus
61. Platelet function, platelet prostanoids and vascular prostacyclin in diabetes mellitus
62. Anti-platelet activity of beta-adrenergic antagonists: inhibition of thromboxane synthesis and platelet aggregation in patients receiving long-term propranolol treatment
63. Platelet function in patients admitted with a diagnosis of myocardial infarction
64. Pharmacology
65. Sural nerve oxygen tension in diabetes
66. Nerve microenvironment in diabetic neuropathy
67. Exercise-induced conduction velocity increment: a marker of impaired peripheral nerve blood flow in diabetic neuropathy
68. The sorbitol pathway and complications of diabetes
69. + ATPase regulation involved in the pathogenesis of diabetic neuropathy?
70. Prostacyclin and noradrenaline in peripheral nerve of chronic experimental diabetes
71. The roles of essential fatty acids in the development of diabetic neuropathy and other complications of diabetes mellitus
72. Essential fatty acids prevent slowed nerve conduction in streptozotocin diabetes
73. Essential fatty acid treatment — effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats
74. The effect of gamma-linolenic acid on diabetic neuropathy: a multicentre trial
75. Effects of fatty acid supplementation on peripheral nerve and skeletal muscle function and capillarization in streptozotocin diabetic rats
76. The effects of evening primrose oil on nerve function and capillarization in streptozotocin-diabetic rats: modulation by the cyclo-oxygenase inhibitor flurbiprofen
77. Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits
78. Effect of niceritol on streptozotocin-induced diabetic neuropathy in rats
79. Clinical biochemistry of essential fatty acids
80. Arterial epigastrico cavernous anastomosis for the treatment of sexual impotence
81. Intracavernous injection of papaverine for erectile failure
82. Cavernosal alpha-blockade: a new technique for investigating and treating erectile impotence
83. Pilot experiments on the actions of drugs injected into the human corpus cavernosum penis
84. Pharmacotherapy of erectile dysfunction: a review
85. 1 for organic impotence
86. 1 for the treatment of erectile impotence
87. 1 in impotent men
88. Prostaglandins in erectile dysfunction
89. 2 in man
90. 1 for impotency
91. 1 and the nitric oxide donor linsidomine for erectile failure: a diagnostic comparative study of 40 patients
92. 2 ratio in arteriogenic impotence
93. Intracavernosal kinetics of eicosanoids and endothelin during erection. Data from human and animal studies on intrapenile and systemic prostaglandins
94. Vascular trauma and prostacyclin release
95. 1 on penile erection and erectile failure
96. 1 in the diagnosis of cavernovenous leakage
97. 1 and visual sexual stimulation
98. 1 stimulation in the diagnosis of arteriogenic impotence
99. 1
100. Eicosanoids and peripheral neurotransmission
101. Intraurethral prostaglandin E-2 cream: a possible alternative treatment for erectile dysfunction
102. Managing impotence in diabetes — no need for separate service