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1
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0002098511
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Katalytische und stöchiometrische enantioselektive Additionen von Diethylzink an Aldehyde mit Hilfe eines neuartigen chiralen Spirotitanats
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Preliminary communications
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(1991)
Angewandte Chemie
, vol.103
, pp. 100-101
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Schmidt1
Seebach2
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3
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0000233048
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2,2-Dimethyl-α,α,α′,α′-tetra(naphth-2-yl)-1,3-dioxolan-4,5-dimethanol (DINOL) für die Titanat-vermittelte, enantioselektive Addition von Diethylzink an Aldehyde
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(1991)
Angewandte Chemie
, vol.103
, pp. 1383-1385
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Schimdt1
Seebach2
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5
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0000389195
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On the Mechanisms of Enantioselective Reactions Using ?,?,??,?? -Tetraaryl-1,3-dioxolane-4,5-dimethanol(TADDOL)-Derived Titanates: Differences betweenC2- andC1-symmetrical TADDOLs - facts, implications and generalizations
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Full paper on the mechanism
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(1992)
Helvetica Chimica Acta
, vol.75
, pp. 2171-2209
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Seebach1
Plattner2
Beck3
Wang4
Hunziker5
Petter6
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6
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0027396039
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For a discussion see, [Tetrahedron-Symposia-in-Print 49 on “Synthesis of Optically Active Compounds - Prospects for the 21st Century”].
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(1993)
Tetrahedron
, vol.49
, pp. 1711-1724
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Seebach1
Hayakawa2
Sakaki3
Schweizer4
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7
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0001202271
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Organische Synthese — wohin?
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A review article describing our view of the future of organic synthesis see
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(1990)
Angewandte Chemie
, vol.102
, pp. 1363-1409
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Seebach1
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9
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0001956304
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Enantioselektive Addition von Organometallreagentien an Carbonylverbindungen: Übertragung, Vervielfältigung und Verstärkung der Chiralität
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Review
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(1991)
Angewandte Chemie
, vol.103
, pp. 34-55
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Noyori1
Kitamura2
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11
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84921168895
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Tetrahedron
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For a general discussion see the introduction in, in print [Tetrahedron-Symposia-in-Print on “Mechanistic Aspects of Polar Organometallic Chemistry”].
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(1993)
Tetrahedron
, vol.49
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Weber1
Seebach2
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24
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84921147197
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9
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25
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84921147196
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Weber, B., hithero unpublished results, ETH Zürich, 1993; see also Scheme 3 in ref.2
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26
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84921147195
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4 may be as small as 1 : 200 for high enantioselectivity to be observed!
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27
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84921147194
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For a complete list of all TADDOLs as of July 1992 see Table 2 in ref.2
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29
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0002291128
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Organometallverbindungen von Titan und Zirconium als selektive nucleophile Reagentien für die Organische Synthese
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(1983)
Angewandte Chemie
, vol.95
, pp. 12-26
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Weidmann1
Seebach2
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38
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84921147193
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21.
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39
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84921147192
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So far, the α-naphthyl-TADDOL was the poorest ligand for the nucleophilic addition to aldehydes described here. ortho-Tolyl- and ortho-methoxyphenyl-TADDOLs have not been tested as yet.
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40
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84921147191
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23 above.
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41
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84921147190
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2
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45
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84918035465
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3-Brom-3-methyl-2-(trimethylsiloxy)-1-buten – ein neues Cycloadditionsreagens
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(1979)
Angewandte Chemie
, vol.91
, pp. 178-259
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]Seebach1
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47
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10344232997
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For a very recent review article see, and references cited therein
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(1993)
LC ·GC Int.
, vol.6
, pp. 606-610
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Hinshaw1
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54
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0002953322
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Synthese von Cyclosporin und Analoga: Zusammenhang zwischen Struktur und immunsuppressiver Aktivität
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(1985)
Angewandte Chemie
, vol.97
, pp. 88-96
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Wenger1
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57
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84921147189
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32
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58
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33947332027
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According to the old-fashioned but widely used Hanson convention re and si are used irrespective whether the face topicities are reflection-variant or reflection-invariant
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(1966)
J. Am. Chem. Soc.
, vol.88
, pp. 2731-2742
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Hanson1
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59
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37049077643
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Nonlinear relationship between the enantioselectivities for asymmetric reactions of monofunctional and bifunctional substrates. Synthesis of practically optically pure diols by the catalytic enantioselective diethylation of terephthalaldehyde
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Cf. Soai's related work with terephthaldehyde
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(1992)
Journal of the Chemical Society, Chemical Communications
, pp. 106-108
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Soai1
Hori2
Kawahara3
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61
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84921147188
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4 to play in the mechanism.
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62
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84921147187
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2. The cyclohexyl derivative is now being tested in other types of reactions, and we hope to obtain the crystal structure of this compound. The results will be reported elsewhere. We gratefully acknowledge receipt of a generous sample of the cyclohexyl analog of 1a from Dr. R. O. Duthaler of the Ciba Company (Basel); the compound was prepared by hydrogenation of the TADDOL 1a: Rothe-Streit, P., Duthaler, R. O., Hafner, A. [[Truncated]]
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71
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84921147186
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Beilsteins Handbuch der Organischen Chemie, 1, E I, 203, E III, 1668.
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72
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84921147185
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Beilsteins Handbuch der Organischen Chemie, 1, E III, 1746.
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73
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84921147184
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Beilsteins Handbuch der Organischen Chemie, 6, E III, 108.
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74
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84921147183
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Beilsteins Handbuch der Organischen Chemie, 6, E II, 504; E III, 1953.
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75
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84921147182
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a, Beilsteins Handbuch der Organischen Chemie, 6, E III, 2465
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77
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84921147181
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a, Beilsteins Handbuch der Organischen Chemie, 6, E III, 2465
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78
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84921147180
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Beilsteins Handbuch der Organischen Chemie, 6, E III, 2741.
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