Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12- hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets

Journal of Biological Chemistry

Volumn 269, Issue 22, 1994, Pages 15619-15624

  Riendeau, D ^a   Guay, J ^a   Weech, P K ^a   Laliberte, F ^a   Yergey, J ^a   Li, C ^a   Desmarais, S ^a   Perrier, H ^a   Liu, S ^a   Nicoll Griffith, D ^a   Street, I P ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ARACHIDONIC ACID; CALCIUM IONOPHORE; ENZYME INHIBITOR; KETONE; PHOSPHOLIPASE A2;

ARTICLE; BIOSYNTHESIS; CELL LINE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; IONTOPHORESIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; THROMBOCYTE ACTIVATION;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ARACHIDONIC ACID; ARACHIDONIC ACIDS; BLOOD PLATELETS; CALCIMYCIN; CALCIUM; CELL LINE; CELL MEMBRANE; CYTOSOL; HUMAN; HYDROXYEICOSATETRAENOIC ACIDS; KINETICS; MOLECULAR WEIGHT; PHOSPHOLIPASES A; THROMBOXANE B2;

EID: 0028272107     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)