Myelodysplastic syndromes in childhood-classification, epidemiology, and treatment

Leukemia and Lymphoma

Volumn 13, Issue 1-2, 1994, Pages 11-26

  Hasle, Henrik ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Childhood; Epidemiology; MDS; Myelodysplasia

Indexed keywords

ALPHA INTERFERON; ANDROGEN; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 3; LYMPHOBLAST ANTIBODY; PREDNISOLONE; RECOMBINANT ERYTHROPOIETIN; RETINOIC ACID; VITAMIN D;

ADOLESCENT; ADULT; ADVERSE DRUG REACTION; ALLOGENIC BONE MARROW TRANSPLANTATION; CANCER CHEMOTHERAPY; CANCER EPIDEMIOLOGY; CANCER SURVIVAL; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME ANALYSIS; CLINICAL TRIAL; DIFFERENTIAL DIAGNOSIS; DISEASE CLASSIFICATION; FEMALE; GENETIC PREDISPOSITION; HUMAN; IMMUNOMODULATION; INFANT; LEUKEMIA REMISSION; MALE; MONOSOMY 7; MYELODYSPLASTIC SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SCHOOL CHILD; SEX DIFFERENCE;

ADOLESCENT; ADULT; AGE FACTORS; ANDROGENS; ANTINEOPLASTIC AGENTS; BONE MARROW TRANSPLANTATION; CHILD; CHROMOSOMES, HUMAN, PAIR 7; COMPARATIVE STUDY; DIAGNOSIS, DIFFERENTIAL; FEMALE; HEMATOPOIETIC CELL GROWTH FACTORS; HUMAN; IMMUNOTHERAPY; INCIDENCE; MALE; MONOSOMY; MYELODYSPLASTIC SYNDROMES; SEX CHARACTERISTICS;

EID: 0028267715     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199409051647     Document Type: Article

References (169)

1. Preleukemia
2. Myelodysplasia
3. Experience in pediatric myelodysplastic syndromes
4. Myelodysplastic syndromes
5. Myelodysplastische Erkrankungenim Kindesalter
6. Myélodysplasies de I'enfant
7. Bone marrow dysfunctions preceding acute leukemia in children: a clinical study
8. Proposals for the classification of the acute leukaemias
9. Proposals for the classifications of the myelodysplastic syn dromes
10. Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Co operative Group
11. Third MIC Cooperative Study Group. Recommen dations for a morphologic, immunologic, and cytogenetic (MIC) working classification for the primary and therapy-related myelodysplastic disorders
12. Prognostic factors in the myelodysplas tic syndromes
13. Analysis of leukocyte differentiation antigens in blood and bone marrow in patients with refractory anaemia (RA) and RA with sideroblasts. Prognostic implications of sequential and follow-up data
14. Childhood myelodysplasia: Suggested classification as my elodysplastic syndromes based on laboratory and clinical finding
15. Myelodysplastic syndromes in childhood. Report of 21 patients from Italy and West Germany
16. My elodysplastic syndromes in childhood: a population based study of nine cases
17. Primary myelodys plastic syndrome in children: the clinical experience in 33 cases
18. Prognostic factors in adult chronic myelo-monocytic leukemia: An analysis of 107 cases
19. Chronic myelomonocytic leukemia according to the FAB classification: Analysis of 35 cases
20. Subacute and chronic myelomonocytic leukemia in children (Juvenile CML)
21. Prognostic factors in juvenile chronic granulocytic leukemia
22. Quantitation of HBF gamma-chain types by HPLC in patients with myelodysplastic syndrome
23. Ph-negative CML: Comparison with Ph+ CML and chronic myelomonocytic leukemia
24. Issues in the pathology of the myelodysplastic syndromes
25. Morphologic classification of the myelodysplastic syndromes (MDS): combined utilization of bone marrow aspirates and trephine biopsies
26. Primary myelodys plastic syndromes: diagnostic and prognostic significance of immunohistochemical assessment of bone marrow biopsies
27. Hypoplastic my elodysplastic syndrome: incidence, morphology, cytogenetics, and prognosis
28. Analysis of karyotype, SCE, and point mutation of RAS oncogene in Indian MDS patients
29. Childhood myelodysplastic syndromes: clinical features, cytogenetics and prognosis
30. Aplastic anaemia and the hypocel-lular myelodysplastic syndrome: Histomorphological, diagnostic, and prognostic features
31. Clonal hematopoiesis in patients with acquired aplastic anemia
32. Absence of point mutation of N-rasoncogene in bone marrow cells with aplastic anemia
33. Bone marrow examination
34. Red cell aplasia in myelodysplastic syndrome
35. Genetic thrombocy-topenia with autosomal transmission: a review of 54 cases
36. Familial thrombocytopenia with micromegakaryocytes
37. Refractory anaemia according to the FAB classification: A report on 69 cases
38. Refractory throm-bocytopenia. A myelodysplastic syndrome that may mimic immune thrombocytopenic purpura
39. Viruses and the blood
40. Viruses and bone marrow failure
41. Indicative morphological myelodysplastic alterations of bone marrow in overt AIDS
42. Bone marrow morphology and proliferative activity in acquired immunodeficiency syndrome
43. The bone marrow in human immunodeficiency virus (HIV)-related disease
44. Myelodysplasia in the acquired immune deficiency syndrome
45. Acute parvovirus B19 infection mimicking myelodysplastic syndrome of the bone marrow
46. Persistent Epstein-Barr virus infection mimicking juvenile chronic myelogenous leukemia: Immunologic and hematologic studies
47. Place de la greffe allogénique de moelle osseuse dans la leucémie myélomonocytaire chronique juvénile
48. Juvenile chronic granulocytic leukemia in a patient with trisomy 8, neurofibromatosis, and prolonged Epstein-Barr virus infection
49. Persistent Epstein-Ban virus infection associated with monosomy 7 or chromosome 3 abnormality in childhood myeloprolif-erative disorders
50. Pearson's marrow-pancreas syndrome in two Turkish children
51. Myelodysplasia and leukemia syndrome with monosomy 7: A genetic perspective
52. Familial myelodysplasia: progressive disease associated with emergence of monosomy 7
53. Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7
54. Myelodysplastic syndromes in two young brothers (Engl abstr)
55. Familial myelodysplasia
56. Down's syndrome—transient abnormal myelopoiesis and acute leukemia
57. Leukemia and transient leukemia in Down syndrome
58. High-dose Ara-C as a single agent consolidation therapy in childhood acute my elogenous leukemia
59. Myelodysplasia (MDS) and acute megakaryoblastic leukemia (AKML) in Down syndrome (abstr)
60. Down's syndrome and acute leukemia in children: An analysis of phenotype by use of monoclonal antibodies and electron microscopic platelet per-oxidase reaction
61. Myelodysplasia as the initial presentation of Fan-coni's anaemia in a phenotypically normal child
62. Myelodysplastic syndrome with trisomy 8 in an adolescent with Fanconi anaemia and selective IgA deficiency
63. Unsuspected Fanconi's anemia and bone marrow transplantation in cases of acute myelomono-cytic leukemia
64. Leukemia and preleukemia in Fanconi's anemia
65. Neurofibromatosis and childhood leukemia
66. Chromosome pattern in juvenile chronic myelogenous leukemia, myelodysplastic syndrome, and acute leukemia associated with neurofibro matosis
67. Monosomy 7 syndrome in an infant with neurofibromatosis
68. Monosomy 7 myeloproliferative disease in children with neurofibromatosis, type l: epidemiology and mo lecular analysis
69. The occurrence of leukemia in patients with the Shwachman syndrome
70. Bloom's syndrome, myelodys plasia, and unclassifiable acute leukemia (abstr)
71. He-matopoietic dysplasia and marrow hypocellularity in chil dren: a preleukemic condition
72. Myelodysplastic syn drome in a patient with a unique constitutional chromosome abnormality t(2;ll) (q31;p13)
73. Therapy-related myelodysplastic syndrome and acutemyeloid leukemia in children: Correlation between chromosomal abnormalities and prior therapy
74. Age-related incidence and other epidemiological aspects of myelodysplastic syndromes
75. Increasing prevalence of the myelodysplastic syndrome. An international delphistudy
76. Myelodysplastic syndromes. A clinical and pathologic analysis of 109 cases
77. Groupe Fran Gais de Morphologie Htmatologique. French registry of acute leukemia and myelodysplastic syndromes
78. Myelodysplastic syndromes in children
79. Preleukemia in children
80. Hhatopcetische dysplasie—Präleukämie
81. Preleukemia in children
82. Prevalence of N-ras mutations in children with myelodys plastic syndromes and acute myeloid leukemia
83. Cytogenetic studies in 112 cases of untreated myelodysplastic syndromes
84. Congenital juvenile chronic myelogenous leukemia: Thera peutic trial with interferon alpha-2
85. Congenital myelodysplasia: A newly described disease entity?
86. Bone marrow transplantation for myelodysplastic and my-eloproliferative syndromes
87. Myélodysplasies régressive de I'enfant
88. Severe refractory anemia with ringed sideroblasts and bone marrow aplasia in a child
89. Refractory sideroblastic and nonsideroblastic anemia
90. Prognostic im portance of cytogenetic subgroups in de novo pediatric acute nonlymphocytic leukemia
91. Clonal karyotype abnormalities and clinical progress in the myelo dysplastic syndrome
92. The 5q- syndrome
93. The occurrence of 5q-syndrome in a child (abstr)
94. Myelo dysplastic syndrome with partial deletion of the long arm of chromosome 5: first report of a case in a child
95. Glucocorticoid therapy in preleukemic syndrome (hemopoi-etic dysplasia)
96. Successful treatment of refractory anaemia with high-dose meth-ylprednisolone
97. Successful immunosuppressive treatment after failure of eryth-ropoietin therapy in two subjects with refractory anaemia
98. Japanese experience in the treatment of myelodysplastic syndromes
99. Hyperfibrotic myelodysplasia
100. Disturbances of T lymphocyte subsets preceding refractory anemia with excess blasts in transformation in a child
101. Anti-thymocyte globulin for hypoplastic myelodysplastic syn drome (abstr)
102. Antilymphocyte globulin for myelodys plastic syndrome?
103. Multiple responses of aplastic anemia to low-dose cyclosporine therapy despite development of a myelodysplastic syndrome
104. Refractory cytopenia: Clinical course according to bone marrow cytology and cellularity
105. Danazol: in vitro effect on human hemopoiesis and in vitro activity in hypoplastic and myelo dysplastic disorders
106. Danazol treatment of myelodysplastic syndromes
107. Differentiation-in ducing agents in the treatment of myelodysplastic syn dromes
108. Differentiation therapy
109. Therapy of ‘high risk’ myelodysplastic syndromes with an association of low-dose Ara-C, retinoic acid and 1,25-dihy-droxyvitamin D3
110. Preliminary experience with 13-cis retinoic acid in the treatment of JCML (abstr)
111. In vivo 13-cis-retinoic acid therapy decreases the in vitro GM-CSF hy-persensitivity in JCML (abstr)
112. Transient response to alpha-interferon in juvenile chronic myelomonocytic leukemia
113. Juvenile chronische Leukamie und chronische) myelornono- zytare Leukamie. Erfahrungen mitder Knochenmarktran-splantat
114. Treatment of advanced myelodysplastic syndromes with recombinant interferon-alpha 2b
115. Phase II trial of recombinant human interferon alpha in myelodysplastic syndromes
116. Effectiveness of recombinant human erythropoietin therapy in myelodysplastic syndromes
117. Phar-macologic doses of recombinant human erythropoietin in the treatment of myelodysplastic syndromes
118. Effect of subcutaneously administered human recombinant erythropoietin on erythropoiesis in patients with myelodysplasia
119. Recombinant human erythropoietin for the treatment of anemia in the my elodysplastic syndromes: a clinical and erythrokinetic as sessment
120. Treatment of my elodysplastic syndromes with cytokines and cytotoxic drugs
121. A randomized phase I/II multicenter study of recombinant GM-CSF therapy for patients with myelodysplastic syndromes and a relatively low risk of acute leukemia
122. Recombinant human granu-locyte-macrophage colony stimulating factor in patients with myelodysplastic syndromes—A phase I/II trial
123. My elodysplasia and leukemia after treatment of aplastic anemia with G-CSF
124. Ran domized trial of subcutaneous GM-CSF versus observation in patients with MDS (abstr)
125. Inter-leukin-3 in the treatment of myelodysplastic syndromes
126. Phase I study of recombinant human interleukin-3 in patients with bone marrow failure
127. Granulocyte-macrophage colony-stimulating factor and interleukin-3 in combination: a potent and consistent myelodysplastic syndrome bone marrow stimulant in vitro
128. Remission of juvenile chronic myeloid leukemia following graft failure of an un related marrow transplant and autologous recovery of mar row function promoted by GM-CSF and IL-3
129. Efficacité de la cytarabine à faible doses après échec d'une chimiothérapie conventionelle
130. Efficacy of low-dose Aracytine in 3 cases of refractory anemia in trans formation in children
131. My elodysplastic syndrome in childhood: Report of a case
132. Treatment of preleukemic syndromes with marrow transplantation
133. An acquired Ber-nard-Soulier-like platelet defect associated with juvenile my elodysplastic syndrome
134. Sequential development of distinct clonal chromosome abnormalities in a patient with preleukaemia
135. A predictive model for the clinical response to low dose ara-C: a study of 102 patients with myelodysplastic syndromes or acute leukaemia
136. The evaluation of low-dose cytarabine in the treatment of myelodysplastic syndromes: a phase-III intergroup study
137. Refractory anemia with excess of blasts in transformation. Hematologic and clinical study of 52 patients
138. Síndrome mielodis-plástico evolucionado a leucemia aguda eritromegaca-rioblática. A propósito de un caso pediátrico
139. A new translocation, t(1;3)(p36;q21), in myelodysplastic disorders
140. AML in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498
141. The value of intensive combination chemo therapy for juvenile chronic myelogenous leukemia
142. Juvenile chronic myelocytic leukemia: Experience with intensive combination chemotherapy
143. Intensive antileukemic treatment of patients younger than 65 years with myelodysplastic syndromes and secondary acute myelogenous leukemia
144. Prognostic factors in adult de novo myelodysplastic syndromes treated by intensive chemotherapy
145. The role of aggressive chemotherapy in the treatment of the myelodys plastic syndromes
146. Efficacy of intensive chemotherapy for acute myelogenous leukemia associated with a preleukemic syndrome
147. Intensive chemotherapy for acute non-lymphoblastic leukemia after primary myelodysplastic syndrome
148. Aggressive chemotherapy combined with G-CSF and maintenance therapy with inter-leukin-2 for patients with advanced myelodysplastic syndrome, subacute or secondary acute myeloid leukemia—initial results
149. Successful treatment of juvenile chronic granulocytic leukemia with marrow transplantation
150. Allogeneic marrow transplantation for children with juvenile chronic myelogenous leukemia
151. Bone marrow transplantation for myelodysplastic syndromes
152. Partially matched bone mar row transplantation in patients with myelodysplastic syndromes
153. Bone marrow transplantation for children with myelodysplastic syndromes
154. Bone marrow transplantation for myelodysplasia and secondary acute non-lymphoblastic leukemia
155. Biclonal chromosome evolution of chronic myelo-monocytic leukemia in a child
156. Al logeneic bone marrow transplantation for myelodysplastic syndromes of childhood: Report of three children with refractory anemia with excess of blasts in transformation and review of the literature
157. Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program
158. Treatment of myelodysplastic syndrome with busulfan-cyclophosphamide conditioning followed by allogeneic BMT
159. Busulfan/cyclo-phosphamide plus bone marrow transplantation is not sufficient to eradicate the malignant clone in juvenile chronic myelogenous leukemia
160. Bone marrow transplantation for patients with myelodysplasia
161. Allogeneic bone marrow trans plantation for secondary leukaemia and myelodysplastic syndrome: a survey by the Leukaemia Working Party of the European Bone Marrow Transplantation Group (EBMTG)
162. Bone marrow trans plantation for myelodysplastic syndrome and secondary leukemia: outcome of 86 patients (abstr)
163. Haematological improvement with conservative management in an infant with myelodysplasia
164. Spontaneous remission of infantile acute non-lymphocytic leukemia for 11 years in a child with normal karyotype
165. Spontaneous remission in myelodysplastic syndrome. A case report
166. Clinical features of long-term survivors of refractory myelodysplastic anemias. A Japanese cooperative study