U73122 inhibits phospholipase C-dependent calcium mobilization in neuronal cells

Brain Research

Volumn 642, Issue 1-2, 1994, Pages 237-243

  Jin, Wenzhen ^a   Lo, Tak Man ^a   Loh, Horace H ^a   Thayer, Stanley A ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Bradykinin; Dorsal root ganglion neuron; Intracellular calcium; NG108 15; Phospholipase C; U73122

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; AMINOSTEROID; PHOSPHOLIPASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

ANIMAL; BRADYKININ; CALCIUM; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; ESTRENES; GANGLIA, SPINAL; NEURONS; NEURONS, AFFERENT; PHOSPHOLIPASE C; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028267089     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(94)90927-X     Document Type: Article

References (31)

1. Characterization of the major phosphoinositide-specific phospholipase C of human amnion
2. Protein kinase C modulation of NMDA currents: an important link for LTP induction
3. Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils
4. 2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor
5. Membrane current responses of NG108-15 mouse neuroblastoma x rat glioma hybrid cells to bradykinin
6. Inositol Trisphosphate/Calcium-Dependent Acetylcholine Release Evoked by Bradykinin in NGlOS-15 Rodent Hybrid Cells
7. Isozyme-selective stimulation of phospholipase C-β2 by G protein ²γ-subunits
8. Second messengers involved in the regulation of corticotropin-releasing hormone mRNA and peptide in cultured rat fetal hypothalamic primary cultures
9. Characterization of bradykinin receptors in guinea pig gall bladder
10. A new generation of calcium indicators with greatly improved fluorescence properties
11. Cerebellar GABAb receptors modulate function of GABAa receptor
12. 2+ sequestration in rat liver cells
13. Dihydropyridine-sensitive and ω-conotoxin-sensitive calcium channels in a mammalian neuroblastoma-glioma cell line
14. Comparison of opiate inhibition of adenylate cyclase activity in neuroblastoma N18TG2 and neuroblastoma x glioma NG108-15 hybrid cell lines
15. Refilling the Inositol 1, 4, 5-trisphosphate-sensitive calcium store in neuroblastoma x glioma hybrid NG108-15 cells
16. Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphate
17. Three types of neuronal calcium channels with different calcium agonist sensitivity
18. U-73122, an aminosteroid phospholipase C antagonist, noncompetitively inhibits thyrotropin-releasing hormone effects in GH3 rat pituitary cells
19. Receptor-coupled signal transduction in human polymophonuclear neutrophils:effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness
20. Postreceptor events associated with human neutrophil activation by interleukin-8
21. Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq
22. Regulation of calcium homeostasis in sensory neurons by bradykinin
23. 2+ transients using simultaneous microfluorimetry and electrophysiology
24. The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells
25. A phospholipase C inhibitor ameliorates postischemic neuronal damage in rats
26. U73122 affects the equlibria between the phosphoinositides as well as phospholipase C activity in unstimulated and thrombin-stimulated human and rabbit platelets
27. Storage stability of water-insoluble enzymes covalently coupled to organic and inorganic carriers
28. ω-Conotoxin exerts functionally distinct low and high affinity effects in the neuronal cell line NG108-15
29. Enhancement of N- and L-type calcium channel currents by protein kinase C in frog sympathetic neurons
30. 2+ oscillations in response to and carbachol but not to JMV-180 in rat pancreatic acinar cells