Dibasic (Amidinoaryl)propanoic Acid Derivatives as Novel Blood Coagulation Factor Xa Inhibitors

Journal of Medicinal Chemistry

Volumn 37, Issue 8, 1994, Pages 1200-1207

  Nagahara, Takayasu ^a   Yokoyama, Yukio ^a   Inamura, Kazue ^a   Katakura, Shin ichi ^a   Komoriya, Satoshi ^a   Yamaguchi, Hitoshi ^a   Hara, Tsuyoshi ^a   Iwamoto, Masahiro ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 [(1 ACETIMIDOYL 3 PYRROLIDINYL)OXY]PHENYL] 3 (7 AMIDINO 2 NAPHTHYL)PROPANOIC ACID; 2 [4 [(1 ACETIMIDOYL 3 PYRROLIDINYL)OXY]PHENYL] 3 (7 AMIDINO 2 NAPHTHYL)PROPIONIC ACID; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10A; PROPIONIC ACID DERIVATIVE; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTICOAGULATION; ARTICLE; CALCIFICATION; DRUG DESIGN; DRUG SYNTHESIS; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PARTIAL THROMBOPLASTIN TIME; RAT;

ANIMAL; ANTICOAGULANTS; BINDING SITES; CALCIUM; COMPUTER SIMULATION; CRYSTALLIZATION; FACTOR XA; MALE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NAPHTHALENES; PARTIAL THROMBOPLASTIN TIME; PROPIONIC ACIDS; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0028265990     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00034a018     Document Type: Article

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