Hepatitis C virus‐RNAs in plasma and in peripheral blood mononuclear cells of hemophiliacs with chronic hepatitis C: Evidence for viral replication in peripheral blood mononuclear cells

Journal of Medical Virology

Volumn 42, Issue 3, 1994, Pages 272-278

  Willems, M ^a   Peerlinck, K ^a   Moshage, H ^a   Deleu, I ^a   Van Den Eynde, C ^a   Vermylen, J ^a   Yap, S H ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

HCV antibodies; negative HCV RNA strands; non B hepatitis; posttransfusion non A

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BLOOD TRANSFUSION; CHILD; CLINICAL ARTICLE; FEMALE; HEMOPHILIA A; HEMOPHILIA B; HEPATITIS C; HUMAN; MALE; PERIPHERAL LYMPHOCYTE; PLASMA; VIRUS REPLICATION;

ADOLESCENT; ADULT; AGED; ALANINE TRANSAMINASE; BASE SEQUENCE; BLOOD TRANSFUSION; CHILD; CHILD, PRESCHOOL; FEMALE; HEMOPHILIA A; HEMOPHILIA B; HEPACIVIRUS; HEPATITIS ANTIBODIES; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS C; HEPATITIS C ANTIBODIES; HEPATITIS, CHRONIC; HIV INFECTIONS; HUMAN; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RNA, VIRAL; RNA-DIRECTED DNA POLYMERASE; SENSITIVITY AND SPECIFICITY; SUPPORT, NON-U.S. GOV'T; VIREMIA; VIRUS REPLICATION;

EID: 0028265067     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.1890420314     Document Type: Article

References (26)

1. Evidence for persistent hepatitis C virus (HCV) infection in hemophiliacs
2. Demonstration of bovine viral diarrhoea virus in peripheral blood mononuclear cells of persistently infected, clinically normal cattle
3. Hepatitis C infection in children with hemophilia A and B
4. Progress in the clinical management of haemophilia
5. Effect of alpha‐interferon therapy on hepatitis C viraemia in community‐acquired chronic non‐A, non‐B hepatitis: A quantitative polymerase chain reaction
6. Flavivirus genome organization, expression and replication
7. Single‐step method of RNA isolation by acid guanidinium thiocyanate‐phenol‐chloroform extraction
8. Reinfection of liver graft by hepatitis C virus after liver transplantation
9. Detection of replicative intermediates of hepatitis C viral RNA in liver and serum of patients with chronic hepatitis C
10. Detection of hepatitis C viral sequences in blood donations by “nested” polymerase chain reaction and prediction of infectivity
11. Demonstration of viraemia patterns in haemophiliacs treated with hepatitis‐C‐virus‐contaminated factor VIII concentrates
12. Characterization of the terminal regions of hepatitis C viral RNA: Identification of conserved sequences in the 5′ untranslated region and poly(A) tails at the 3′ end
13. Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease
14. Detection of gene expression by PCR amplification of RNA derived from frozen heparinized whole blood
15. Hepatitis C antibody and chronic liver disease in haemophilia
16. Recurrence of hepatitis C virus infection after chronic orthotopic liver transplantation
17. Hepatitis C virus shares ammo acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups
18. Minus strand RNA of hepatitis C virus in liver tissues
19. Detection of the minus strand of hepatitis C virus RNA by reverse transcription and polymerase chain reaction: Implications for hepatitis C virus replication in infected tissue
20. Reverse transcription and direct amplification of cellular RNA transcripts by Taq polymerase
21. Detection of hepatitis C viral sequences in non‐A, non‐B hepatitis
22. Surrogate markers are not useful for identification of HCV carriers in chronic hemodialysis patients
23. Plasma collected from heparinized blood is not suitable for HCV‐RNA detection by conventional RT‐PCR assay
24. 5′End‐dependent translation initiation of hepatitis C viral RNA and the presence of putative positive and negative translational control elements within the 5′untranslated region
25. Infection of peripheral blood mononuclear cells by hepatitis C virus