메뉴 건너뛰기




Volumn 93, Issue 6, 1994, Pages 2738-2743

Retrobulbar T cells from patients with Graves' ophthalmopathy are CD8+ and specifically recognize autologous fibroblasts

Author keywords

cytokines; fibroblasts; Graves' disease; ophthalmopathy; T lymphocytes

Indexed keywords

ALLOANTIGEN; AUTOANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; INTERLEUKIN 10; INTERLEUKIN 4; TISSUE EXTRACT; TUBERCULIN;

EID: 0028263893     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI117289     Document Type: Article
Times cited : (133)

References (40)
  • 1
    • 0007548782 scopus 로고
    • Ophthalmopathy
    • L. E. Braverman and R. D. Utiger, editors. J. B. Lippineott Co., Philadelphia
    • Gorman, C. A., R. S. Bahn, and J. A. Garrity. 1991. Ophthalmopathy. In The Thyroid. L. E. Braverman and R. D. Utiger, editors. J. B. Lippineott Co., Philadelphia. 657-676.
    • (1991) The Thyroid , pp. 657-676
    • Gorman, C.A.1    Bahn, R.S.2    Garrity, J.A.3
  • 2
    • 0025735484 scopus 로고
    • Thyroid-associated eye disease: Clinical management
    • Fells, P. 1991. Thyroid-associated eye disease: clinical management. Lancet. 338:29-32.
    • (1991) Lancet , vol.338 , pp. 29-32
    • Fells, P.1
  • 3
    • 0025877388 scopus 로고
    • Thyroid-associated eye disease: Pathophysiology
    • Weetman, A. P. 1991. Thyroid-associated eye disease: pathophysiology. Lancet. 338:25-28.
    • (1991) Lancet , vol.338 , pp. 25-28
    • Weetman, A.P.1
  • 4
    • 0027459740 scopus 로고
    • Detection and localization of cytokine immunoreactivity in retro-ocular connective tissue in Graves' ophthalmopathy
    • Heufelder, A. E., and R. S. Bahn. 1993. Detection and localization of cytokine immunoreactivity in retro-ocular connective tissue in Graves' ophthalmopathy. Eur. J. Clin. Invest. 23:10-17.
    • (1993) Eur. J. Clin. Invest. , vol.23 , pp. 10-17
    • Heufelder, A.E.1    Bahn, R.S.2
  • 5
    • 0024559311 scopus 로고
    • Immunohistochemical analysis of the retrobulbar tissues in Graves' ophthalmopathy
    • Weetman, A. P., S. Cohen, K. C. Gatter, P. Fells, and B. Shine. 1989. Immunohistochemical analysis of the retrobulbar tissues in Graves' ophthalmopathy. Clin. Exp. Immunol. 75:222-227.
    • (1989) Clin. Exp. Immunol. , vol.75 , pp. 222-227
    • Weetman, A.P.1    Cohen, S.2    Gatter, K.C.3    Fells, P.4    Shine, B.5
  • 6
    • 0013939895 scopus 로고
    • Dysthyroid ocular myopathy
    • Kroll, A. J., and T. Kuwabara. 1966. Dysthyroid ocular myopathy. Arch Ophthalmol 27:244-249.
    • (1966) Arch Ophthalmol , vol.27 , pp. 244-249
    • Kroll, A.J.1    Kuwabara, T.2
  • 7
    • 0021677254 scopus 로고
    • Immunohistochemical and ultrastructural studies on the exenterated orbital tissues of a patient with Graves' disease
    • Hufnagl, T. J., W. F. Hickey, N. H. Cobbs, F. A. Jacobiec, T. Iwamo, and R. C. Eagle. 1984. Immunohistochemical and ultrastructural studies on the exenterated orbital tissues of a patient with Graves' disease. Ophthalmology. 94:1411-1417.
    • (1984) Ophthalmology , vol.94 , pp. 1411-1417
    • Hufnagl, T.J.1    Hickey, W.F.2    Cobbs, N.H.3    Jacobiec, F.A.4    Iwamo, T.5    Eagle, R.C.6
  • 8
    • 76549249753 scopus 로고
    • Experiences with malignant exophthalmus
    • Falconer, M. A., and W. S. Alexander. 1951. Experiences with malignant exophthalmus. Br. J. Ophthalmol. 35:253-259.
    • (1951) Br. J. Ophthalmol. , vol.35 , pp. 253-259
    • Falconer, M.A.1    Alexander, W.S.2
  • 9
    • 0024790151 scopus 로고
    • Immunology of Graves' ophthalmopathy: Retrobulbar histology and histochemistry
    • Campbell, J. C. 1989. Immunology of Graves' ophthalmopathy: retrobulbar histology and histochemistry. Acta Endocrinol. 121 (Suppl.):9-16.
    • (1989) Acta Endocrinol. , vol.121 , Issue.SUPPL. , pp. 9-16
    • Campbell, J.C.1
  • 10
    • 0020458199 scopus 로고
    • Demonstration of a circulating autoantibody against a soluble eye-muscle antigen in Graves' ophthalmopathy
    • Kodama, K., H. Sikorska, P. Bandy-Dafoe, R. Bayly, and J. R. Wall. 1982. Demonstration of a circulating autoantibody against a soluble eye-muscle antigen in Graves' ophthalmopathy. Lancet, ii:1353-1356.
    • (1982) Lancet , vol.2 , pp. 1353-1356
    • Kodama, K.1    Sikorska, H.2    Bandy-Dafoe, P.3    Bayly, R.4    Wall, J.R.5
  • 11
    • 0021135837 scopus 로고
    • Ophthalmopathic immunoglobulin in patients with Graves' ophthalmopathy
    • Atkinson, S., M. Holcombe, and P. Kendall-Taylor. 1984. Ophthalmopathic immunoglobulin in patients with Graves' ophthalmopathy. Lancet. ii:374-376.
    • (1984) Lancet , vol.2 , pp. 374-376
    • Atkinson, S.1    Holcombe, M.2    Kendall-Taylor, P.3
  • 13
    • 0024801136 scopus 로고
    • The central role of fibroblasts in the pathogenesis of extrathyroidal manifestations of Graves' disease
    • Bahn, R. S., T. J. Smith, and C. A. Gorman. 1989. The central role of fibroblasts in the pathogenesis of extrathyroidal manifestations of Graves' disease. Acta Endocrinol. 121:75-81.
    • (1989) Acta Endocrinol. , vol.121 , pp. 75-81
    • Bahn, R.S.1    Smith, T.J.2    Gorman, C.A.3
  • 14
    • 0024436440 scopus 로고
    • Presence of antibodies in the sera of patients with Graves' disease recognizing a 23 kilodalton fibroblast protein
    • Bahn, R. S., C. A. Gorman, C. M. Johnson, and T. J. Smith. 1989. Presence of antibodies in the sera of patients with Graves' disease recognizing a 23 kilodalton fibroblast protein. J. Clin. Endocrinol. & Metab. 69:622-628.
    • (1989) J. Clin. Endocrinol. & Metab. , vol.69 , pp. 622-628
    • Bahn, R.S.1    Gorman, C.A.2    Johnson, C.M.3    Smith, T.J.4
  • 15
    • 0023930006 scopus 로고
    • Human orbital tissue and thyroid membranes express a 64 kDa protein which is recognized by autoantibodiesin the serum of patients with thyroid-associated ophthalmopathy
    • Salvi, M., A. Miller, and J. R. Wall. 1988. Human orbital tissue and thyroid membranes express a 64 kDa protein which is recognized by autoantibodiesin the serum of patients with thyroid-associated ophthalmopathy. FEBS(Fed. Eur Biochem Soc.) Lett. 232:135-139.
    • (1988) FEBS(Fed. Eur Biochem Soc.) Lett. , vol.232 , pp. 135-139
    • Salvi, M.1    Miller, A.2    Wall, J.R.3
  • 16
    • 0022600961 scopus 로고
    • Ability of monoclonal antibodies to the thyrotropin receptor to increase collagen synthesis in human fibroblasts: An assay which appears to measure exophthalmogenic immunoglobulins in Graves' sera
    • Rotella, C. M., R. Zonefrati, R. Toccafondi, W. A. Valente, and L. D. Kohn. 1986. Ability of monoclonal antibodies to the thyrotropin receptor to increase collagen synthesis in human fibroblasts: an assay which appears to measure exophthalmogenic immunoglobulins in Graves' sera. J. Clin. Endocrinol. & Metab. 62:357-367.
    • (1986) J. Clin. Endocrinol. & Metab. , vol.62 , pp. 357-367
    • Rotella, C.M.1    Zonefrati, R.2    Toccafondi, R.3    Valente, W.A.4    Kohn, L.D.5
  • 17
    • 0025824113 scopus 로고
    • Modulation of HLA-DR expression on retroocular fibroblasts from patients with active thyroid-related ophthalmopathy: In vitro effects of agents used in the management of hyperthyroidism and ophthalmopathy
    • Heufelder, A. E., C. A. Gorman, and R. S. Bahn. 1991. Modulation of HLA-DR expression on retroocular fibroblasts from patients with active thyroid-related ophthalmopathy: in vitro effects of agents used in the management of hyperthyroidism and ophthalmopathy. J. Clin. Endocrinol. & Metab. 97:206-209.
    • (1991) J. Clin. Endocrinol. & Metab. , vol.97 , pp. 206-209
    • Heufelder, A.E.1    Gorman, C.A.2    Bahn, R.S.3
  • 18
    • 0025997595 scopus 로고
    • Detection, cellular localization, and modulation of heat shock proteins in cultured fibroblasts from patients with extrathyroidal manifestations of Graves' disease
    • Heufelder, A. E., B. J. Wenzel, C. A. German, and R. S. Bahn. 1991. Detection, cellular localization, and modulation of heat shock proteins in cultured fibroblasts from patients with extrathyroidal manifestations of Graves' disease. J. Clin. Endocrinol. & Metab. 73:739-745.
    • (1991) J. Clin. Endocrinol. & Metab. , vol.73 , pp. 739-745
    • Heufelder, A.E.1    Wenzel, B.J.2    German, C.A.3    Bahn, R.S.4
  • 19
  • 20
    • 0027305697 scopus 로고
    • Do heat shock proteins play a role in Graves' disease? Heat shock protein specific T cells do not recognize thyroid epithelial cells
    • Trieb, K., A. Sztankay, M. Hermann, R. Gratzl, J. Szabo, S. Jindal, and B. Grubeck-Loebenstein. 1993. Do heat shock proteins play a role in Graves' disease? Heat shock protein specific T cells do not recognize thyroid epithelial cells. J. Clin. Endocrinol. & Metab. 77:528-535.
    • (1993) J. Clin. Endocrinol. & Metab. , vol.77 , pp. 528-535
    • Trieb, K.1    Sztankay, A.2    Hermann, M.3    Gratzl, R.4    Szabo, J.5    Jindal, S.6    Grubeck-Loebenstein, B.7
  • 22
    • 0024334774 scopus 로고
    • T and B cell reactivity to extraocular and skeletal muscle in Graves' ophthalmopathy
    • Weetman, A. P., P. Fells, and B. Shine. 1989. T and B cell reactivity to extraocular and skeletal muscle in Graves' ophthalmopathy. Br. J. Ophthalmol. 73:323-331.
    • (1989) Br. J. Ophthalmol. , vol.73 , pp. 323-331
    • Weetman, A.P.1    Fells, P.2    Shine, B.3
  • 23
    • 0015785004 scopus 로고
    • Cell-mediated immunity in the exophthalmus of Graves' disease as demonstrated by the migration inhibitor factor (MIF) test
    • Munro, R. E., L. Lamki, V. V. Row, and B. Volpé. 1973. Cell-mediated immunity in the exophthalmus of Graves' disease as demonstrated by the migration inhibitor factor (MIF) test. J. Clin. Endocrinol. & Metab. 37:286-292.
    • (1973) J. Clin. Endocrinol. & Metab. , vol.37 , pp. 286-292
    • Munro, R.E.1    Lamki, L.2    Row, V.V.3    Volpé, B.4
  • 24
    • 0023721656 scopus 로고
    • Efficient propagation and cloning of human T cells in the absence of antigen by means of OKT3, interleukin 2, and antigen-presenting cells
    • Londei, M., B. Grubeck-Loebenstein, P. de Berardinis, C. Greenall, and M. Feldmann. 1988. Efficient propagation and cloning of human T cells in the absence of antigen by means of OKT3, interleukin 2, and antigen-presenting cells. Scand. J. Immunol. 27:35-46.
    • (1988) Scand. J. Immunol. , vol.27 , pp. 35-46
    • Londei, M.1    Grubeck-Loebenstein, B.2    De Berardinis, P.3    Greenall, C.4    Feldmann, M.5
  • 25
    • 0026785932 scopus 로고
    • Regulation of interleukin-4 production in human mononuclear cells
    • Holter, W., O. Majdic, F. S. Kalthoff, and W. Knapp. 1992. Regulation of interleukin-4 production in human mononuclear cells. Eur. J. Immunol. 22:2765-2769.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2765-2769
    • Holter, W.1    Majdic, O.2    Kalthoff, F.S.3    Knapp, W.4
  • 28
    • 0026469344 scopus 로고
    • Human Th1 and Th2 subsets: Regulation of differon and role in protection and immunopathology
    • Romagnani, R. 1992. Human Th1 and Th2 subsets: regulation of differon and role in protection and immunopathology. Int. Arch. Allergy Immunol. 98:279-284.
    • (1992) Int. Arch. Allergy Immunol. , vol.98 , pp. 279-284
    • Romagnani, R.1
  • 31
    • 0026514309 scopus 로고
    • Differential effects of interleukin-4 and-10 on IL-2 induced interferon-γ synthesis and lymphokine-activated killer activity
    • Hsu, D. H., K. W. Moore, and H. Spits. 1992. Differential effects of interleukin-4 and-10 on IL-2 induced interferon-γ synthesis and lymphokine-activated killer activity. Int. Immunol. 4:563-569.
    • (1992) Int. Immunol. , vol.4 , pp. 563-569
    • Hsu, D.H.1    Moore, K.W.2    Spits, H.3
  • 32
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • de Waal Malefyt, R., J. Haanen, H. Spits, M.-G. Roncarolo, A. te Velde, C. Figdor, K. Johnson, R. Kastelein, H. Yssel, and J. E. de Vries. 1991. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174:915-924.
    • (1991) J. Exp. Med. , vol.174 , pp. 915-924
    • Waal Malefyt, R.1    Haanen, J.2    Spits, H.3    Roncarolo, M.-G.4    Te Velde, A.5    Figdor, C.6    Johnson, K.7    Kastelein, R.8    Yssel, H.9    De Vries, J.E.10
  • 33
    • 0025772012 scopus 로고
    • Stimulation of glycosaminoglycan accumulation by interferon-gamma in cultured human retrocular fibroblasts
    • Smith, T. J., R. S. Bahn, and C. A. Gorman. 1991. Stimulation of glycosaminoglycan accumulation by interferon-gamma in cultured human retrocular fibroblasts. J. Clin. Endocrinol. & Metab. 72:1169-1174.
    • (1991) J. Clin. Endocrinol. & Metab. , vol.72 , pp. 1169-1174
    • Smith, T.J.1    Bahn, R.S.2    Gorman, C.A.3
  • 34
    • 0017683621 scopus 로고
    • Glycosaminoglycan synthesis by cultured human skin fibroblasts after transformation with simian virus 40
    • Hopwood, J. J., and A. Dorfmann. 1977. Glycosaminoglycan synthesis by cultured human skin fibroblasts after transformation with simian virus 40. J. Biol. Chem. 252:4777-4783.
    • (1977) J. Biol. Chem. , vol.252 , pp. 4777-4783
    • Hopwood, J.J.1    Dorfmann, A.2
  • 38
    • 0025869958 scopus 로고
    • Defects in monocyte polarization and dendritic cell clustering in patients with Graves' disease. A putative role for a non-specific immunoregulatory factor related to retroviral p15E
    • Tas, M., M. de Haan-Meulman, P. J. Kabel, and H. A. Drexhage. 1991. Defects in monocyte polarization and dendritic cell clustering in patients with Graves' disease. A putative role for a non-specific immunoregulatory factor related to retroviral p15E. Clin. Endocrinol 34:441-449.
    • (1991) Clin. Endocrinol , vol.34 , pp. 441-449
    • Tas, M.1    De Haan-Meulman, M.2    Kabel, P.J.3    Drexhage, H.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.