Structure-Activity Relationships for Contact Allergenic Potential of γ,γ-Dimethyl-γ-butyrolactone Derivatives. 1. Synthesis and Electrophilic Reactivity Studies of α-(ω-Substituted-alkyl) -γ,γ-dimethyl-γ-butyrolactones and Correlation of Skin Sensitization Potential and Cross-Sensitization Patterns with Structure

Chemical Research in Toxicology

Volumn 7, Issue 3, 1994, Pages 297-306

  Franot, Christelle ^a,b,c   Roberts, David W ^a,b   Smith, Richard G ^a,b   Basketter, David A ^a,b   Benezra, Claude ^a,b,c   Lepoittevin, Jean Pierre ^a,b,c  

^a CNRS   (France)

^b UNILEVER RESEARCH   (United Kingdom)

^c UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA (3 BROMOPROPYL) GAMMA,GAMMA DIMETHYLBUTYROLACTONE; CONTACT ALLERGEN; LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ALLERGENICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL REACTION; CONTACT ALLERGY; GUINEA PIG; NONHUMAN; SKIN SENSITIZATION; SKIN TEST; STRUCTURE ACTIVITY RELATION;

4-BUTYROLACTONE; ALLERGENS; ANIMAL; ANTIBODY SPECIFICITY; CHEMISTRY, PHYSICAL; CROSS REACTIONS; DERMATITIS, ALLERGIC CONTACT; GUINEA PIGS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; SKIN TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0028260272     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx00039a005     Document Type: Article

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