FR901228, a novel antitumor bicyclic depsipeptide produced by chromobacterium violaceum no. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

The Journal of Antibiotics

Volumn 47, Issue 3, 1994, Pages 301-310

  Ueda, Hirotsugu ^a   Nakajima, Hidenori ^a   Hori, Yasuhiro ^a   Fujita, Takashi ^a   Nishimura, Makoto ^a   Goto, Toshio ^a   Okuhara, Masakuni ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DEPSIPEPTIDE; FR 901228; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CARBON NUCLEAR MAGNETIC RESONANCE; CELL TRANSFORMATION; CHROMOBACTERIUM; COLON ADENOCARCINOMA; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; FEMALE; FERMENTATION; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; LUNG ADENOCARCINOMA; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; ONCOGENE H RAS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STOMACH ADENOCARCINOMA; TAXONOMY;

3T3 CELLS; ADENOCARCINOMA; ANIMAL; ANTIBIOTICS, ANTINEOPLASTIC; ANTIBIOTICS, PEPTIDE; CARCINOMA; CELL LINE, TRANSFORMED; CHROMOBACTERIUM; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; FERMENTATION; HUMAN; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, NUDE; MICROBIAL SENSITIVITY TESTS; NEOPLASM TRANSPLANTATION; TACROLIMUS; TUMOR CELLS, CULTURED;

EID: 0028258610     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.7164/antibiotics.47.301     Document Type: Article

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