Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione

Journal of Neuroscience

Volumn 14, Issue 7, 1994, Pages 4385-4392

  Ratan, Rajiv R ^a   Murphy, Timothy H ^a,b   Baraban, Jay M ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

apoptosis; cortical neurons; cycloheximide; cyst(e)ine; glutamate; glutathione; oxidative stress

Indexed keywords

ACETYLCYSTEINE; ANISOMYCIN; BUTHIONINE SULFOXIMINE; CYCLOHEXIMIDE; CYSTINE; DACTINOMYCIN; DIMETHYL SULFOXIDE; GLUTATHIONE; HOMOCYSTEIC ACID; IDEBENONE; LACTATE DEHYDROGENASE; SULFUR 35;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CORTEX; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME RELEASE; FETUS; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RAT;

EID: 0028246870     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.14-07-04385.1994     Document Type: Article

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