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Volumn 35, Issue 28, 1994, Pages 4967-4968

An improved method of oxazolidinone hydrolysis in the asymmetric synthesis of α-alkylprolines

Author keywords

[No Author keywords available]

Indexed keywords

OXAZOLIDINONE DERIVATIVE; PROLINE DERIVATIVE;

EID: 0028244615     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)73294-1     Document Type: Article
Times cited : (18)

References (15)
  • 1
    • 0000093325 scopus 로고
    • Enantioselective Generation and Diastereoselective Reactions of Chiral Enolates Derived from ?-Heterosubstituted Carboxylic Acids. Preliminary Communication
    • (1981) Helvetica Chimica Acta , vol.64 , pp. 2704-2708
    • Seebach1    Naef2
  • 10
    • 84913036990 scopus 로고    scopus 로고
    • 2O. The α-alkylated proline product was isolated by filtration as a white solid in high yield.
  • 11
    • 84913023137 scopus 로고    scopus 로고
    • D −106° (c 1.35, MeOH).
  • 12
    • 84913045875 scopus 로고    scopus 로고
    • 2O in a closed environment often results in additional product crystallization.
  • 13
    • 84913026469 scopus 로고    scopus 로고
    • 2O) δ 7.21–7.45 (m, 5 H, Ph), 3.69,4.37 (s, 1 H), 3.43 (d, J = 14.7 Hz, 1 H), 3.01 (d, J = 14.7 Hz, 1 H), 3.32 (t, J = 7.5 Hz, 2 H), 2.41–2.47 (m, 1 H), 1.86–2.16 (m, 3H), 1.01–1.10 (m, 9 H).
  • 14
    • 84913077127 scopus 로고    scopus 로고
    • 1H NMR.
  • 15
    • 84913034015 scopus 로고    scopus 로고
    • 3OD) δ 3.68 (s, 3 H), 3.46–3.53 (m, 1 H), 3.22–3.32 (m, 1 H), 3.27 (d, J = 17.1 Hz, 1 H), 2.82 (d, J = 17.1 Hz, 1 H), 2.27–2.31 (m, 1 H), 1.89–2.01 (m, 3H).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.