Enantiospecific synthesis of 2-amino-3-methyl-4-phosphonobutanoic acids via 14-addition of lithiated Schöllkopf anion to prop-2-enylphosphonates

Tetrahedron Letters

Volumn 35, Issue 20, 1994, Pages 3273-3276

  Ojea, Vicente ^a   Ruiz, María ^a   Shapiro, Gideon ^a   Pombo Villar, Esteban ^a  

^a Preclinical Research Sandoz Pharma Ltd ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3 METHYL 4 PHOSPHONOBUTYRIC ACID; PHOSPHONOAMINO ACID; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENANTIOMER; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0028240870     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)76883-3     Document Type: Article

References (24)

1. New Synthesis of Diethyl Auylphosphonates and Diethyl Alkenylphosphonates
2. Synthesis and Wittig-Horner Reactions of 1-(Functionally)Substituted 2,2-Dimethylpropanephosphonic Esters (1-t-Butyl-substituted Phosphonic Esters)
3. Addition of Lithium Dialkylcuprates to α,β-Unsaturated Phosphoryl Compounds
4. 278. The reaction between trialkyl phosphites and alkyl halides
5. Palladium-catalyzed new carbon-phosphorus bond formation.
6. Asymmetric Synthesis via Heterocyclic Intermediates; XXX1. Asymmetric Synthesis of Glutamic Acids and Derivatives thereof by the Bislactim-Ether Method. Michael-Addition of Methyl 2-Alkenoates to the Lithiated Bislactim-Ether of Cyclo-(L-Val- Gly)
7. Enantio- und diastereoselektive Synthese von (2R)-2-Amino-5-oxocarbonsäure-methylestern aus Enonen und Bislactimether-Cupraten
8. Enantioselective Syntheses of(R)-Amino Acids UsingL-Valine as Chiral Agent
9. Preparation and Conformational Analysis of Geometric Isomers of 4,5-Dimethyl-2-ethoxy-2-oxo-1,2-oxaphosphorinane and Their 3,3,6,6-Tetradeuterio Analogs.