메뉴 건너뛰기




Volumn 3, Issue 2, 1994, Pages 83-92

Overexpression of p53 protein in squamous cell carcinomas of head and neck without apparent gene mutations

Author keywords

Head and neck cancer; Immunohistochemistry; p53; PCR SSCP; Squamous cell carcinoma

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; PROTEIN P53;

EID: 0028239526     PISSN: 10529551     EISSN: 15334066     Source Type: Journal    
DOI: 10.1097/00019606-199406000-00004     Document Type: Article
Times cited : (77)

References (36)
  • 2
    • 0024536654 scopus 로고
    • Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
    • Baker SJ, Fearon ER, Nigro JM, et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 1989; 244: 217-21.
    • (1989) Science , vol.244 , pp. 217-221
    • Baker, S.J.1    Fearon, E.R.2    Nigro, J.M.3
  • 3
    • 0022483186 scopus 로고
    • Isolation of human- p53-specific monoclonal antibodies and their use in the studies of human p53 expression
    • Banks L, Matlashewski G, Crawford L. Isolation of human- p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur J Biochem 1986; 159:529-34.
    • (1986) Eur J Biochem , vol.159 , pp. 529-534
    • Banks, L.1    Matlashewski, G.2    Crawford, L.3
  • 4
    • 0025221197 scopus 로고
    • Patterns of expression of the p53 tumor suppressor in human breast tissues and tumor in situ and in vitro
    • Bartek J, Bartkova J, Vojtesek B, Staskova Z, Rejthar A, Kovarik J, Lane DP. Patterns of expression of the p53 tumor suppressor in human breast tissues and tumor in situ and in vitro. Int J Cancer 1990;46:839-44.
    • (1990) Int J Cancer , vol.46 , pp. 839-844
    • Bartek, J.1    Bartkova, J.2    Vojtesek, B.3    Staskova, Z.4    Rejthar, A.5    Kovarik, J.6    Lane, D.P.7
  • 5
    • 0025367297 scopus 로고
    • Genetic and immu nochemical analysis of mutant p53 in human breast cancer cell lines
    • Bartek J, Iggo R, Gannon J, Lane DP. Genetic and immu nochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene 1990; 5: 893-9.
    • (1990) Oncogene , vol.5 , pp. 893-899
    • Bartek, J.1    Iggo, R.2    Gannon, J.3    Lane, D.P.4
  • 7
    • 0026737285 scopus 로고
    • Occurrence of p53 gene deletions and human papillomavirus infection in human head and neck cancer
    • Brachman DG, Graves D, Vokes E, et al. Occurrence of p53 gene deletions and human papillomavirus infection in human head and neck cancer. Cancer Res 1992; 52: 4832-6.
    • (1992) Cancer Res , vol.52 , pp. 4832-4836
    • Brachman, D.G.1    Graves, D.2    Vokes, E.3
  • 8
    • 0023709002 scopus 로고
    • A variation in the structure of the protein-coding region of p53 gene
    • Buchman VL, Chumakov NN, Ninkina OP, Gerogiev GP. A variation in the structure of the protein-coding region of p53 gene. Gene 1988; 70: 245-52.
    • (1988) Gene , vol.70 , pp. 245-252
    • Buchman, V.L.1    Chumakov, N.N.2    Ninkina, O.P.3    Gerogiev, G.P.4
  • 11
    • 0026793723 scopus 로고
    • Maestro R, et al. P53 overexpression is an early event in the development of human squamous cell carcinoma of the larynx: Genetic and prognostic implications
    • Dolcetti R, Doflioni C, Maestro R, et al. p53 overexpression is an early event in the development of human squamous cell carcinoma of the larynx: genetic and prognostic implications. Int J Canter 1992; 53: 178-82.
    • (1992) Int J Canter , vol.53 , pp. 178-182
    • Dolcetti, R.1    Doflioni, C.2
  • 12
    • 0025738297 scopus 로고
    • Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck
    • Feild JK, Spandidos DA, Malliri A, Yiagnisis GM, Stell PM. Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck. Br J Cancer 1991; 64: 573-7.
    • (1991) Br J Cancer , vol.64 , pp. 573-577
    • Feild, J.K.1    Spandidos, D.A.2    Malliri, A.3    Yiagnisis, G.M.4    Stell, P.M.5
  • 13
    • 0025248598 scopus 로고
    • Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form
    • Gannon JV, Greaves T, Iggo R, Lane DP. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J 1990; 9: 1595-1602.
    • (1990) EMBO J , vol.9 , pp. 1595-1602
    • Gannon, J.V.1    Greaves, T.2    Iggo, R.3    Lane, D.P.4
  • 15
    • 0025941313 scopus 로고
    • Expression of p53 in premalignant and malignant squamous epithelium
    • Gusterson BA, Anbazhagan R, Warren W, et al. Expression of p53 in premalignant and malignant squamous epithelium. Oncogene 1991; 6: 1785-9.
    • (1991) Oncogene , vol.6 , pp. 1785-1789
    • Gusterson, B.A.1    Anbazhagan, R.2    Warren, W.3
  • 16
    • 0019401161 scopus 로고
    • Monoclonal antibodies specific for simian virus 40 tumor antigens
    • Harlow ED, Crawford LV, Pirn DC, Willamson NM. Monoclonal antibodies specific for simian virus 40 tumor antigens. I Virol 1981; 39: 861-9.
    • (1981) I Virol , vol.39 , pp. 861-869
    • Harlow, E.D.1    Crawford, L.V.2    Pirn, D.C.3    Willamson, N.M.4
  • 17
    • 0025894713 scopus 로고
    • Harris CC. P53 mutations in human cancers
    • Hollstein M, Sidransky D, Vogelstein B, Harris CC. p53 mutations in human cancers. Science 1991; 253: 49-53.
    • (1991) Science , vol.253 , pp. 49-53
    • Hollstein, M.1    Sidransky, D.2    Vogelstein, B.3
  • 18
    • 0025265724 scopus 로고
    • Increased expression of mutant forms of p53 oncogene in primary lung cancer
    • Iggo R, Gatter K, Bartek J, Lane D, Harris AL. Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet 1990; 335: 675-9.
    • (1990) Lancet , vol.335 , pp. 675-679
    • Iggo, R.1    Gatter, K.2    Bartek, J.3    Lane, D.4    Harris, A.L.5
  • 19
    • 0022569594 scopus 로고
    • Characterization of the human p53 gene
    • Lamb P, Crawford L. Characterization of the human p53 gene. Mol Cell Biol 1986; 6: 1379-85.
    • (1986) Mol Cell Biol , vol.6 , pp. 1379-1385
    • Lamb, P.1    Crawford, L.2
  • 20
    • 0025173845 scopus 로고
    • Benchimol S. P53: Oncogene or antioncogene'?
    • Lane DP, Benchimol S. p53: oncogene or antioncogene'? Gene Dev 1990; 4: 1-8.
    • (1990) Gene Dev , vol.4 , pp. 1-8
    • Lane, D.P.1
  • 21
  • 22
    • 0026507159 scopus 로고
    • High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx
    • Maestro R, Dolectti R, Gasparotto D, et al. High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx. Oncogene 1992; 7: 1159-66.
    • (1992) Oncogene , vol.7 , pp. 1159-1166
    • Maestro, R.1    Dolectti, R.2    Gasparotto, D.3
  • 23
    • 0026694826 scopus 로고
    • Two distinct mechanisms alter p53 in breast cancer: Mutation and nuclear exclusion
    • Moll UM, Riou G, Levine AJ. Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci USA 1992; 89: 7262-6.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7262-7266
    • Moll, U.M.1    Riou, G.2    Levine, A.J.3
  • 24
    • 0024595101 scopus 로고
    • Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
    • Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 1989; 86: 2766-70.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2766-2770
    • Orita, M.1    Iwahana, H.2    Kanazawa, H.3    Hayashi, K.4    Sekiya, T.5
  • 25
    • 0023902853 scopus 로고
    • Estimates of the worldwide frequency of sixteen major cancers in 1980
    • Parkin DM, Laara E, Muire CS. Estimates of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer 1988; 41: 184-97.
    • (1988) Int J Cancer , vol.41 , pp. 184-197
    • Parkin, D.M.1    Laara, E.2    Muire, C.S.3
  • 29
    • 0024452546 scopus 로고
    • A frequent target for genetic abnormalities in lung cancer
    • et al. p53
    • Takahashi T, Nau MM, Chiba I, et al. p53 a frequent target for genetic abnormalities in lung cancer. Science 1989, 246: 491-4.
    • (1989) Science , vol.246 , pp. 491-494
    • Takahashi, T.1    Nau, M.M.2    Chiba, I.3
  • 30
    • 0022537047 scopus 로고
    • Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex
    • Tan T-H, Wallis J, Levine AJ. Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex. J Virol 1986; 59: 574-83.
    • (1986) J Virol , vol.59 , pp. 574-583
    • Tan, T.-H.1    Wallis, J.2    Levine, A.J.3
  • 31
    • 0026608857 scopus 로고
    • Condie A, et al. P53 allele losses, mutations and expression in breast cancer and their relationship to clinico-pathological parameters
    • Thompson AM, Anderson TJ, Condie A, et al. p53 allele losses, mutations and expression in breast cancer and their relationship to clinico-pathological parameters. Ini J Cancer 1992; 50: 528-32.
    • (1992) Ini J Cancer , vol.50 , pp. 528-532
    • Thompson, A.M.1    Erson, T.J.2
  • 32
    • 0026718812 scopus 로고
    • The p53 tumor suppressor protein, a modulator of cell proliferation
    • Ullrich SJ, Anderson CW, Mercer WE, Appella E. The p53 tumor suppressor protein, a modulator of cell proliferation. J Biol Chem 1992; 267: 15259-62.
    • (1992) J Biol Chem , vol.267 , pp. 15259-15262
    • Ullrich, S.J.1    Erson, C.W.2    Mercer, W.E.3    Appella, E.4
  • 33
    • 0022033631 scopus 로고
    • Precise epitope mapping of the murine transformations-associated protein, p53
    • Wade-Evans A, Jenkins JR. Precise epitope mapping of the murine transformations-associated protein, p53. EMBO J 1985; 4: 699-706.
    • (1985) EMBO J , vol.4 , pp. 699-706
    • Wade-Evans, A.1    Jenkins, J.R.2
  • 34
    • 0027513248 scopus 로고
    • Loss of 17p, mutation of the p53 gene, and overexpression of p53 protein in esophageal squamous cell carcinomas
    • et al
    • Wagata T, Shibagaki I, Imamura M, et al Loss of 17p, mutation of the p53 gene, and overexpression of p53 protein in esophageal squamous cell carcinomas. Cancer Res 1993; 53: 846-50.
    • (1993) Cancer Res , vol.53 , pp. 846-850
    • Wagata, T.1    Shibagaki, I.2    Imamura, M.3
  • 35
    • 0026055172 scopus 로고
    • Expression of p53 protein in infiltrating and in-situ breast carcinomas
    • Walker RA, Dearing SJ, Lane DP, Varley JM. Expression of p53 protein in infiltrating and in-situ breast carcinomas. J Pathol 1991; 165: 203-11.
    • (1991) J Pathol , vol.165 , pp. 203-211
    • Walker, R.A.1    Dearing, S.J.2    Lane, D.P.3    Varley, J.M.4
  • 36
    • 0023860029 scopus 로고
    • The surgical pathology of head and neck cancer
    • Zarbo RJ, Crissman JD. The surgical pathology of head and neck cancer. Semin Oncol 1988; 15: 10-19.
    • (1988) Semin Oncol , vol.15 , pp. 10-19
    • Zarbo, R.J.1    Crissman, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.