Synthesis of 2β-Acyl-3β-aryl-8-azabicyclo[3.2.1]octanes and Their Binding Affinities at Dopamine and Serotonin Transport Sites in Rat Striatum and Frontal Cortex

Journal of Medicinal Chemistry

Volumn 37, Issue 9, 1994, Pages 1262-1268

  Davies, Huw M L ^a,b,c   Saikali, Elie ^a,b,c   Huby, Nicholas J S ^a,b,c   Gilliatt, Vernon J ^a,b,c   Matasi, Julius J ^a,b,c   Sexton, Tammy ^a,b,c   Childers, Steven R ^a,b,c  

^a WAKE FOREST UNIVERSITY   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c Department of Chemistry ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; CARRIER PROTEIN; COCAINE; COCAINE DERIVATIVE; DOPAMINE; SEROTONIN; TROPANE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; CORPUS STRIATUM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; ENANTIOMER; FRONTAL CORTEX; MALE; NERVE CELL MEMBRANE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

ANIMAL; BINDING SITES; BINDING, COMPETITIVE; CARRIER PROTEINS; COCAINE; CORPUS STRIATUM; FRONTAL LOBE; MALE; MEMBRANE GLYCOPROTEINS; MOLECULAR STRUCTURE; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RHODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRITIUM;

EID: 0028237668     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00035a005     Document Type: Article

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