Altered surface marker expression and function of G-CSF-induced neutrophils from test subjects and patients under chemotherapy

British Journal of Haematology

Volumn 87, Issue 1, 1994, Pages 31-38

  Spiekermann, K ^a   Emmendoerffer, A ^a   Elsner, J ^a   Raeder, E ^a   Lohmann Matthes , M L ^a   Prahst, A ^a   Link, H ^a   Freund, M ^a   Welte, K ^a   Roesler, J ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

Author keywords

chemotaxis; chemotherapy; Fc receptors; G CSF; neutrophils

Indexed keywords

ANTINEOPLASTIC AGENT; CD14 ANTIGEN; FC RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; INTERCELLULAR ADHESION MOLECULE 1; MEMBRANE ANTIGEN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ARTICLE; CANCER CHEMOTHERAPY; CELL MOTILITY; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; NEUTROPENIA; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0028237099     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2141.1994.tb04866.x     Document Type: Article

References (32)

1. Asano, S., Shirafuji, N., Watari, K., Matsuda, N., Uemura, R., Ieki, R., Kodo, H. & Takaku, F. (1988) Phase I clinical study for recombinant human granulocyte colony‐stimulating factor. Behring Institut Mitteilungen, 83, 222–228.
2. Babcock, G.F., Alexander, J.W. & Warden, G.D. (1990) Flow cytometric analysis of neutrophil subsets in themally injured patients developing infection. Clinical Immunology and Immunopathology, 54, 117–125.
3. Boros, P., Gardos, E., Bekesi, G.J. & Unkeless, J.C. (1990) Change in expression of Fc gamma RIII (CDI6) on neutrophils from human immunodeficiency virus‐infected individuals. Clinical Immunology and Immunopathology, 54, 281–289.
4. Bronchud, M.H., Potter, M.R., Morgenstern, G., Blasco, M.J., Scafle, J.H., Thatcher, N., Crowther, D., Souza, L.M., Alton, N.K., Testa, N.G. & Dexter, T.M. (1988) In vitro and in vivo analysis of the effects of recombinant human granulocyte colony‐stimulating factor in patients. British Journal of Cancer, 58, 64–69.
5. Buckle, A.M. & Hogg, N. (1989) The effect of IFN‐gamma and colonystimulating factors on the expression of neutrophil cell membrane receptors. Journal of Immunology, 143, 2295–2301.
6. Buckle, A.M., Jayaram, Y. & Hogg, N. (1990) Colony‐stimulating factors and interferon‐gamma differentially affect cell surface molecules shared by monocytes and neutrophils. Clinical and Experimental Immunology, 81, 339–345.
7. Elsner, J., Roesler, J., Emmendoerffer, A., Lohmann‐Matthes, M.L. & Welte, K. (1993) Abnormal regulation in the signal transduction in neutrophils from patients with severe congenital neutropenia: relation of impaired mobilization of cytosolic free calcium to altered chemotaxis, superoxide anion generation and F‐actin content. Experimental Hematology, 21. 38–46.
8. Elsner, J., Roesler, J., Emmendoefler, A., Zeidler, C., Lohmann‐Matthes, M.L. & Welte, K. (1992) Altered function and surface marker expression of neutrophils induced by rhG‐CSF treatment in severe congenital neutropenia. European Journal of Haematology, 48, 10–19.
9. Ferrante, A. & Thong, Y.H. (1980) Optimal conditions for simultaneous purification of mononuclear and polymorphonuclear leukocytes from human blood by the Hypaque‐Ficoll method. Journal of Immunological Methods, 36, 109–117.
10. Fleit, H.B., Wright, S.D., Durie, C.J., Valinsky, J.E. & Unkeless, J.C. (1984) Ontogeny of Fc receptors and complement receptor (CR3) during human myeloid differentiation. Journal of Clinical Investigation, 73, 516–525.
11. Freund, M.R., Luft, S., Schober, C., Heussner, P., Schrezenmaier, H., Porzsolt, F. & Welte, K. (1990) Differential effect of GM‐CSF and G‐CSF in cyclic neutropenia. Lancet, 336, 313.
12. Gabrilove, J.L., Jakubowski, A., Fain, K., Grous, J., Scher, H., Sternberg, C., Yagoda, A., Clarkson, B., Bonilla, M.A., Oettgen, H.F., Alton, K., Boone, T., Altrock, B., Welte, K. & Souza, L. (1988) Phase I study of granulocyte colony‐stimulating factor in patients with transitional cell carcinoma of the urothelium. Journal of Clinical Investigation, 82, 1454–1461.
13. Guyre, P.M., Campbell, A.S., Kniffin, W.D. & Fanger, M.W, (1990) Monocytes and polymorphonuclear neutrophils of patients with streptococcal pharyngitis express increased numbers of type I IgG Fc receptors. Journal of Clinical Investigation, 86, 1892–1896.
14. Huizinga, T.W., Van‐der‐Schoot, C.E., Jost, C., Klaassen, R., Kleijer, M., Von‐dem‐Borne, A.E., Roos, D. & Tetteroo, P.A. (1988) The PIlinked receptor FcRIII is released on stimulation of neutrophils. Nature, 333, 667–669.
15. Jablons, D., Bolton, E., Mertins, S., Rubin, M., Pizzo, P., Rosenberg, S.A. & Lotze, M.T. (1990) IL‐2‐based immunotherapy alters circulating neutrophil Fc receptor expression and chemotaxis. Journal of Immunology, 144, 3630–3636.
16. Jayram, Y. & Hogg, N. (1989) Surface expression of CD14 molecules on human neutrophils. Leukocyte Typing IV, (ed. by W. Knappet al). p. 765. Oxford University Press.
17. Kerst, J.M., Van De Winkel, J.C.J., Evans, A.H., De Haas, M., Slaper‐Cortenbach, I.C.M., De Wit, T.P.M., Von Dem Borne, A.E.G.Kr., Van Der Schoot, C.E. & Van Oers, R.H.J. (1993) Granulocyte colonystimulating factor induces hFc gamma RI (CD64 antigen)‐positive neutrophils via an effect on myeloid precursor cells. Blood, 81, 1457–1464.
18. Lieschke, G.J. & Burgess, A.W. (1992) Granulocyte colony‐stimulating factor and granulocyte‐macrophage colony‐stimulating factor (1). New England Journal of Medicine, 327, 28–35.
19. Lindemann, A., Hermann, F., Oster, W., Haffner, G., Meyenburg, W., Souza, L.M. & Mertelsmann, R. (1989) Hematologic effects of recombinant human granulocyte colony‐stimulating factor in patients with malignancy. Blood, 74, 2644–2651.
20. Majima, T., Minegishi, N., Nagatomi, R., Ohashi, Y., Tsuchiya, S., Kobayashi, K. & Konno, T. (1990) Unusual expression of IgG Fc receptors on peripheral granulocytes from patients with leukocyte adhesion deficiency (CD11/CD18 deficiency). Journal of Immunology, 145, 1694–1699.
21. Morstyn, G., Campbell, L., Duhrsen, U., Souza, L.M., Alton, N.K., Villeval, J.L., Nicola, N.A., Boyd, A.W., Kannourakis, G., Cebon, J., Thomas, R., Boyd, J., Keech, J., Green, M., Sheridan, W., Metcalf, D. & Fox, R. (1988) Clinical studies with granulocyte colony stimulating factor (G‐CSF) in patients receiving cytotoxic chemotherapy. Behring Institut Mitteilungen, 234–239.
22. Nelson, R.D., Quie, P.G. & Simmons, R.L. (1975) Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of polymorphonucleated leukocytes and monocytes. Journal of Immunology, 15, 1560–1565.
23. Ohsaka, A., Kitagawa, S., Sakamoto, S., Miura, Y., Takanashi, N., Takaku, F. & Saito, M. (1989) In vivo activation of human neutrophil functions by administration of recombinant human granulocyte colony‐stimulating factor in patients with malignant lymphoma. Blood, 74, 2743–2748.
24. Price, T.H., Chatta, G.S. & Dale, D.C. (1992) The effect of recombinant granulocyte‐colony stimulating factor (G‐CSF) on neutrophil kinetics in normal human subjects. (Abstract). Blood, 80, 350a.
25. Repp, R., Valerius, T., Sendler, A., Gramatzki, M., Iro, H., Kalden, J.R. & Platzer, E. (1991) Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony‐stimulating factor. Blood, 78, 885–889.
26. Roesler, J., Emmendoerffer, A., Eisner, J., Zeidler, C., Lohmann‐Matthes, M. & Welte, K. (1991) In vitro functions of neutrophils induced by treatment with rhG‐CSF in severe congenital neutropenia. European Journal of Haematology, 46, 112–118.
27. Schroten, H., Roesler, J., Breidenbach, T., Wendel, U., Elsner, J., Schweitzer, S., Zeidler, C., Burdach, S., Lohmann Matthes, M.L., Wahn, V. & Welte, K. (1991) Granulocyte and granulocytemacrophage colony‐stimulating factors for treatment of neutropenia in glycogen storage disease type Ib. Journal of Pediatrics, 119, 748–754.
28. Smith, J.B., Campbell, D.E., Ludomirsky, A., Polin, R.A., Douglas, S.D., Garty, B.Z. & Harris, M.C. (1990) Expression of the complement receptors CRl and CR3 and the type III Fc gamma receptor on neutrophils from newborn infants and from fetuses with Rh disease. Pediatric Research, 28, 120–126.
29. Wawrik, S.O., Novotny, J.R., Wicks, I.P., Wilkinson, D., Maher, D., Salvaris, E., Welch, K., Fecondo, J. & Boyd, A.W. (1989) The role of the LFA‐1/ICAM‐1 interaction in human leukocyte homing and adhesion. Immunological Reviews, 108, 135–161.
30. Welte, K., Bonilla, M.A., Gillio, A.P., Boone, T.C., Potter, G.K., Gabrilove, J.L., Moore, M.A.S., O'Reilly, R.J. & Souza, L.M. (1987) Recombinant human granulocyte colony‐stimulating factor. Journal of Experimental Medicine, 165, 941–948.
31. Welte, K., Zeidler, C., Reiter, A., Mueller, W., Odenwald, E., Souza, L. & Riehm, H. (1990) Differential effects of granulocyte‐macrophage colony‐stimulating factor and granulocyte colony‐stimulating factor in children with severe congenital neutropenia. Blood, 75, 1056–1063.
32. White‐Owen, C., Alexander, J.W. & Babcock, G.F. (1992) Reduced expression of neutrophil CD11 b and CD16 after severe traumatic injury. Journal of Surgery Research, 52, 22–26.