Screening of unsubstituted cyclic compounds as inhibitors of monoamine oxidases

Biochemical Pharmacology

Volumn 47, Issue 12, 1994, Pages 2307-2310

  Thull, Ulrike ^a   Testa, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

monoamine oxidases (MAO); unsubstituted arenes; unsubstituted azaheterocycles; unsubstituted oxaheterocycles; xanthone

Indexed keywords

4 CHROMANONE DERIVATIVE; ACRIDINE DERIVATIVE; ACRIDONE DERIVATIVE; AMINE OXIDASE (FLAVIN CONTAINING); ANTHRACENE; ANTHRAQUINONE; CARBAZOLE DERIVATIVE; CLORGYLINE; COUMARIN; DIBENZOFURAN; FLAVONE; MONOAMINE OXIDASE INHIBITOR; NAPHTHALENE; PHENANTHRENE; QUINOLINE DERIVATIVE; SELEGILINE; THIOXANTHENE; XANTHENE; XANTHENE DERIVATIVE;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; DRUG INHIBITION; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMAL; BRAIN; CHROMONES; COMPARATIVE STUDY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FLAVONES; MITOCHONDRIA; MONOAMINE OXIDASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; XANTHENES;

EID: 0028236905     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(94)90271-2     Document Type: Article

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12. Protein measurement with the Folin phenol reagent
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14. A rapid spectrophotometric assay of monoamine oxidase based on the rate of disappearance of kynuramine
15. Statistical analysis of enzyme kinetic data
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19. Enzyme kinetics in relation to enzyme inhibitors
20. Quinoline and quinaldine as naturally occurring inhibitors specific for type A monoamine oxidase